CA1015754A - Furo-(2,3d) pyrimidines, preparation process and therapeutic applications thereof - Google Patents
Furo-(2,3d) pyrimidines, preparation process and therapeutic applications thereofInfo
- Publication number
- CA1015754A CA1015754A CA210,451A CA210451A CA1015754A CA 1015754 A CA1015754 A CA 1015754A CA 210451 A CA210451 A CA 210451A CA 1015754 A CA1015754 A CA 1015754A
- Authority
- CA
- Canada
- Prior art keywords
- furo
- pyrimidines
- preparation process
- therapeutic applications
- therapeutic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7335190A FR2245349A1 (en) | 1973-10-02 | 1973-10-02 | Therapeutic furo (2,3-d)-pyrimidine derivs - have anti-ulcer, analgesic, anti-inflammatory, hypertensive etc. activity |
FR7417484A FR2271823A2 (en) | 1974-05-20 | 1974-05-20 | Therapeutic furo (2,3-d)-pyrimidine derivs - have anti-ulcer, analgesic, anti-inflammatory, hypertensive etc. activity |
Publications (1)
Publication Number | Publication Date |
---|---|
CA1015754A true CA1015754A (en) | 1977-08-16 |
Family
ID=26217960
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA210,451A Expired CA1015754A (en) | 1973-10-02 | 1974-10-01 | Furo-(2,3d) pyrimidines, preparation process and therapeutic applications thereof |
Country Status (11)
Country | Link |
---|---|
US (1) | US4007187A (ru) |
JP (1) | JPS5076091A (ru) |
CA (1) | CA1015754A (ru) |
CH (1) | CH592668A5 (ru) |
DE (1) | DE2446593A1 (ru) |
ES (1) | ES430051A1 (ru) |
GB (1) | GB1430720A (ru) |
LU (1) | LU71010A1 (ru) |
NL (1) | NL7413033A (ru) |
SE (1) | SE7412346L (ru) |
SU (1) | SU581868A3 (ru) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4199584A (en) * | 1977-05-27 | 1980-04-22 | Imperial Chemical Industries Limited | Pesticidal active furo[2,3-d] pyrimidine derivatives, compositions containing the same and use thereof |
US5137879A (en) * | 1990-03-30 | 1992-08-11 | Dowelanco | Furopyrimidin-4-imine derivatives |
US6608053B2 (en) * | 2000-04-27 | 2003-08-19 | Yamanouchi Pharmaceutical Co., Ltd. | Fused heteroaryl derivatives |
DE10148883A1 (de) * | 2001-10-04 | 2003-04-10 | Merck Patent Gmbh | Pyrimidinderivate |
GB0423653D0 (en) * | 2004-10-25 | 2004-11-24 | Piramed Ltd | Pharmaceutical compounds |
ATE471940T1 (de) | 2006-04-26 | 2010-07-15 | Hoffmann La Roche | Thienoä3,2-düpyrimidin-derivat geeignet als pi3k inhibitor |
TW200801012A (en) | 2006-04-26 | 2008-01-01 | Piramed Ltd | Phosphoinositide 3-kinase inhibitor compounds and methods of use |
AU2007243457B2 (en) | 2006-04-26 | 2012-02-23 | F. Hoffmann-La Roche Ag | Pharmaceutical compounds |
JP5284977B2 (ja) | 2006-12-07 | 2013-09-11 | エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト | ホスホイノシチド3−キナーゼ阻害剤化合物及び使用方法 |
BRPI0717907A2 (pt) * | 2006-12-07 | 2013-11-05 | Genentech Inc | "composto, composição farmacêutica, métodos para tratar um câncer, para inbir ou modular a atividade da lipídeo quinase, processo para a produçãoo de uma composição farmacêutica, uso de um composto e kit" |
WO2009055730A1 (en) * | 2007-10-25 | 2009-04-30 | Genentech, Inc. | Process for making thienopyrimidine compounds |
GB0721095D0 (en) * | 2007-10-26 | 2007-12-05 | Piramed Ltd | Pharmaceutical compounds |
CA2761445A1 (en) | 2009-05-27 | 2010-12-02 | Genentech, Inc. | Bicyclic pyrimidine pi3k inhibitor compounds selective for p110 delta, and methods of use |
EP2451811A1 (en) * | 2009-05-27 | 2012-05-16 | F. Hoffmann-La Roche AG | Bicyclic indole-pyrimidine pi3k inhibitor compounds selective for p110 delta, and methods of use |
CA2776944A1 (en) * | 2009-10-12 | 2011-05-12 | F. Hoffmann-La Roche Ag | Combinations of a pi3k inhibitor and a mek inhibitor |
CN102260270A (zh) * | 2010-05-28 | 2011-11-30 | 中国科学院上海药物研究所 | N-(2-甲基呋喃[2,3-d]嘧啶-4-基)丙烯酰胺、其制备方法及其用途 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA705417A (en) * | 1965-03-09 | H. Hitchings George | Pyrrolopyrimidine vasodilators and method of making them | |
US3037980A (en) * | 1955-08-18 | 1962-06-05 | Burroughs Wellcome Co | Pyrrolopyrimidine vasodilators and method of making them |
GB915303A (en) * | 1958-03-13 | 1963-01-09 | Wellcome Found | Pyrrolo[2,3-d]pyrimidine derivatives and the manufacture thereof |
-
1974
- 1974-08-29 CH CH1177974A patent/CH592668A5/xx not_active IP Right Cessation
- 1974-09-13 GB GB3995074A patent/GB1430720A/en not_active Expired
- 1974-09-14 ES ES430051A patent/ES430051A1/es not_active Expired
- 1974-09-17 US US05/506,826 patent/US4007187A/en not_active Expired - Lifetime
- 1974-09-26 LU LU71010A patent/LU71010A1/xx unknown
- 1974-09-30 DE DE19742446593 patent/DE2446593A1/de active Pending
- 1974-10-01 SU SU7402063645A patent/SU581868A3/ru active
- 1974-10-01 JP JP49113222A patent/JPS5076091A/ja active Pending
- 1974-10-01 SE SE7412346A patent/SE7412346L/xx unknown
- 1974-10-01 CA CA210,451A patent/CA1015754A/en not_active Expired
- 1974-10-02 NL NL7413033A patent/NL7413033A/xx not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
ES430051A1 (es) | 1976-10-01 |
LU71010A1 (ru) | 1975-06-16 |
SU581868A3 (ru) | 1977-11-25 |
US4007187A (en) | 1977-02-08 |
DE2446593A1 (de) | 1975-04-03 |
NL7413033A (nl) | 1975-04-04 |
JPS5076091A (ru) | 1975-06-21 |
SE7412346L (ru) | 1975-04-03 |
AU7364874A (en) | 1976-04-01 |
CH592668A5 (ru) | 1977-10-31 |
GB1430720A (en) | 1976-04-07 |
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