ZA991024B - Apparatus and method for inhibiting restenosis by applying ultrasonic energy together with drugs. - Google Patents

Apparatus and method for inhibiting restenosis by applying ultrasonic energy together with drugs.

Info

Publication number
ZA991024B
ZA991024B ZA9901024A ZA991024A ZA991024B ZA 991024 B ZA991024 B ZA 991024B ZA 9901024 A ZA9901024 A ZA 9901024A ZA 991024 A ZA991024 A ZA 991024A ZA 991024 B ZA991024 B ZA 991024B
Authority
ZA
South Africa
Prior art keywords
drugs
ultrasonic energy
applying ultrasonic
inhibiting restenosis
energy together
Prior art date
Application number
ZA9901024A
Other languages
English (en)
Inventor
Uri Rosenschein
L Arie Rozeszjan
Original Assignee
Angiosonics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Angiosonics Inc filed Critical Angiosonics Inc
Publication of ZA991024B publication Critical patent/ZA991024B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A61B17/22004—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for using mechanical vibrations, e.g. ultrasonic shock waves
    • A61B17/22012—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for using mechanical vibrations, e.g. ultrasonic shock waves in direct contact with, or very close to, the obstruction or concrement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0092—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin using ultrasonic, sonic or infrasonic vibrations, e.g. phonophoresis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A61B17/22004—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for using mechanical vibrations, e.g. ultrasonic shock waves
    • A61B2017/22005—Effects, e.g. on tissue
    • A61B2017/22007—Cavitation or pseudocavitation, i.e. creation of gas bubbles generating a secondary shock wave when collapsing
    • A61B2017/22008—Cavitation or pseudocavitation, i.e. creation of gas bubbles generating a secondary shock wave when collapsing used or promoted
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A61B2017/22082—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for after introduction of a substance
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A61B2017/22082—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for after introduction of a substance
    • A61B2017/22088—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for after introduction of a substance ultrasound absorbing, drug activated by ultrasound

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Medical Informatics (AREA)
  • Organic Chemistry (AREA)
  • Mechanical Engineering (AREA)
  • Vascular Medicine (AREA)
  • Molecular Biology (AREA)
  • Cardiology (AREA)
  • Dermatology (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA9901024A 1998-02-10 1999-02-09 Apparatus and method for inhibiting restenosis by applying ultrasonic energy together with drugs. ZA991024B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US2116298A 1998-02-10 1998-02-10

Publications (1)

Publication Number Publication Date
ZA991024B true ZA991024B (en) 2000-01-14

Family

ID=21802701

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9901024A ZA991024B (en) 1998-02-10 1999-02-09 Apparatus and method for inhibiting restenosis by applying ultrasonic energy together with drugs.

Country Status (7)

Country Link
EP (1) EP1054633A1 (ja)
JP (1) JP2002502804A (ja)
AR (1) AR014555A1 (ja)
AU (1) AU2494199A (ja)
CA (1) CA2320300A1 (ja)
WO (1) WO1999039647A1 (ja)
ZA (1) ZA991024B (ja)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6582392B1 (en) 1998-05-01 2003-06-24 Ekos Corporation Ultrasound assembly for use with a catheter
US20040097996A1 (en) 1999-10-05 2004-05-20 Omnisonics Medical Technologies, Inc. Apparatus and method of removing occlusions using an ultrasonic medical device operating in a transverse mode
ATE319378T1 (de) 2001-12-03 2006-03-15 Ekos Corp Katheter mit mehreren ultraschall-abstrahlenden teilen
US8226629B1 (en) 2002-04-01 2012-07-24 Ekos Corporation Ultrasonic catheter power control
CA2535981C (en) * 2003-09-08 2014-10-28 Board Of Trustees Of The University Of Arkansas Ultrasound apparatus and method for augmented clot lysis
WO2005072409A2 (en) 2004-01-29 2005-08-11 Ekos Corporation Method and apparatus for detecting vascular conditions with a catheter
US7794414B2 (en) 2004-02-09 2010-09-14 Emigrant Bank, N.A. Apparatus and method for an ultrasonic medical device operating in torsional and transverse modes
EP2015846A2 (en) 2006-04-24 2009-01-21 Ekos Corporation Ultrasound therapy system
US10188410B2 (en) 2007-01-08 2019-01-29 Ekos Corporation Power parameters for ultrasonic catheter
US10182833B2 (en) 2007-01-08 2019-01-22 Ekos Corporation Power parameters for ultrasonic catheter
US9044568B2 (en) 2007-06-22 2015-06-02 Ekos Corporation Method and apparatus for treatment of intracranial hemorrhages
WO2011003031A1 (en) 2009-07-03 2011-01-06 Ekos Corporation Power parameters for ultrasonic catheter
US8740835B2 (en) 2010-02-17 2014-06-03 Ekos Corporation Treatment of vascular occlusions using ultrasonic energy and microbubbles
CN105361923B (zh) 2010-08-27 2018-02-02 Ekos公司 用于治疗颅内出血的方法和设备
US11458290B2 (en) 2011-05-11 2022-10-04 Ekos Corporation Ultrasound system
US20160030725A1 (en) 2013-03-14 2016-02-04 Ekos Corporation Method and apparatus for treatment of intracranial hemorrhages
US10092742B2 (en) 2014-09-22 2018-10-09 Ekos Corporation Catheter system
EP3307388B1 (en) 2015-06-10 2022-06-22 Ekos Corporation Ultrasound catheter

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4474180A (en) 1982-05-13 1984-10-02 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Apparatus for disintegrating kidney stones
US4870953A (en) 1987-11-13 1989-10-03 Donmicheal T Anthony Intravascular ultrasonic catheter/probe and method for treating intravascular blockage
US5163421A (en) 1988-01-22 1992-11-17 Angiosonics, Inc. In vivo ultrasonic system with angioplasty and ultrasonic contrast imaging
US5324255A (en) 1991-01-11 1994-06-28 Baxter International Inc. Angioplasty and ablative devices having onboard ultrasound components and devices and methods for utilizing ultrasound to treat or prevent vasopasm
US5811447A (en) * 1993-01-28 1998-09-22 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5524620A (en) 1991-11-12 1996-06-11 November Technologies Ltd. Ablation of blood thrombi by means of acoustic energy
US5269297A (en) 1992-02-27 1993-12-14 Angiosonics Inc. Ultrasonic transmission apparatus
US5362309A (en) * 1992-09-14 1994-11-08 Coraje, Inc. Apparatus and method for enhanced intravascular phonophoresis including dissolution of intravascular blockage and concomitant inhibition of restenosis
CA2145093C (en) 1992-09-25 2007-04-10 Lawrence Leroy Kunz Therapeutic inhibitor of vascular smooth muscle cells
EP0710116B1 (en) 1993-05-13 2008-09-03 Poniard Pharmaceuticals, Inc. Prevention and treatment of pathologies associated with abnormally proliferative smooth muscle cells

Also Published As

Publication number Publication date
CA2320300A1 (en) 1999-08-12
AU2494199A (en) 1999-08-23
EP1054633A1 (en) 2000-11-29
JP2002502804A (ja) 2002-01-29
WO1999039647A1 (en) 1999-08-12
AR014555A1 (es) 2001-02-28

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