ZA988053B - Novel carboxylic acid derivatives, their preparation and use as mixed ETA/ETB receptor antagonists. - Google Patents

Novel carboxylic acid derivatives, their preparation and use as mixed ETA/ETB receptor antagonists.

Info

Publication number
ZA988053B
ZA988053B ZA9808053A ZA988053A ZA988053B ZA 988053 B ZA988053 B ZA 988053B ZA 9808053 A ZA9808053 A ZA 9808053A ZA 988053 A ZA988053 A ZA 988053A ZA 988053 B ZA988053 B ZA 988053B
Authority
ZA
South Africa
Prior art keywords
preparation
carboxylic acid
acid derivatives
receptor antagonists
etb receptor
Prior art date
Application number
ZA9808053A
Inventor
Wilhelm Amberg
Rolf Jansen
Dagmar Klinge
Hartmut Riechers
Stefan Hergenroeder
Manfred Raschack
Liliane Unger
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag filed Critical Basf Ag
Publication of ZA988053B publication Critical patent/ZA988053B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/34—One oxygen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52—Two oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA9808053A 1997-09-04 1998-09-03 Novel carboxylic acid derivatives, their preparation and use as mixed ETA/ETB receptor antagonists. ZA988053B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19738578A DE19738578A1 (en) 1997-09-04 1997-09-04 Carboxylic acid derivatives useful as endothelin A and B antagonists also active as renin and angiotensin inhibitors

Publications (1)

Publication Number Publication Date
ZA988053B true ZA988053B (en) 2000-03-22

Family

ID=7841110

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9808053A ZA988053B (en) 1997-09-04 1998-09-03 Novel carboxylic acid derivatives, their preparation and use as mixed ETA/ETB receptor antagonists.

Country Status (2)

Country Link
DE (1) DE19738578A1 (en)
ZA (1) ZA988053B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6638937B2 (en) 1998-07-06 2003-10-28 Bristol-Myers Squibb Co. Biphenyl sulfonamides as dual angiotensin endothelin receptor antagonists

Also Published As

Publication number Publication date
DE19738578A1 (en) 1999-03-11

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