ZA987436B - Method of increasing oral bioavailability of compounds - Google Patents

Method of increasing oral bioavailability of compounds

Info

Publication number
ZA987436B
ZA987436B ZA987436A ZA987436A ZA987436B ZA 987436 B ZA987436 B ZA 987436B ZA 987436 A ZA987436 A ZA 987436A ZA 987436 A ZA987436 A ZA 987436A ZA 987436 B ZA987436 B ZA 987436B
Authority
ZA
South Africa
Prior art keywords
oral bioavailability
compounds
compound
increasing oral
grapefruit juice
Prior art date
Application number
ZA987436A
Other languages
English (en)
Inventor
Kan He
Paul Hollenberg
Thomas F Woolf
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of ZA987436B publication Critical patent/ZA987436B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
    • A61K31/37—Coumarins, e.g. psoralen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
ZA987436A 1997-08-19 1998-08-18 Method of increasing oral bioavailability of compounds ZA987436B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US5612997P 1997-08-19 1997-08-19

Publications (1)

Publication Number Publication Date
ZA987436B true ZA987436B (en) 1999-02-22

Family

ID=22002350

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA987436A ZA987436B (en) 1997-08-19 1998-08-18 Method of increasing oral bioavailability of compounds

Country Status (15)

Country Link
US (1) US6509371B1 (xx)
EP (1) EP1007034B1 (xx)
JP (1) JP2001515035A (xx)
KR (1) KR100510809B1 (xx)
AT (1) ATE253357T1 (xx)
AU (1) AU747051B2 (xx)
BR (1) BR9812131A (xx)
CA (1) CA2291233C (xx)
DE (1) DE69819519T2 (xx)
DK (1) DK1007034T3 (xx)
ES (1) ES2209184T3 (xx)
NZ (1) NZ502668A (xx)
PT (1) PT1007034E (xx)
WO (1) WO1999008676A1 (xx)
ZA (1) ZA987436B (xx)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE1014575A3 (fr) * 2002-01-16 2004-01-13 Chapelle Andre Composition a base de 5,7 dmc et/ou de bergamottine.
US7169763B2 (en) * 2002-02-22 2007-01-30 Oliver Yoa-Pu Hu Cytochrome P450 3A inhibitors and enhancers
EP1847266B1 (en) 2005-01-21 2013-12-25 ARKRAY, Inc. Metabolic syndrome-improving agent and medicine, supplement, functional food and food additive containing the same
JP4902964B2 (ja) * 2005-03-30 2012-03-21 株式会社ファンケル 薬物の代謝阻害剤とその使用
EP3003288A1 (en) 2013-05-30 2016-04-13 Nanobiotix Pharmaceutical composition, preparation and uses thereof
WO2016083338A1 (en) * 2014-11-25 2016-06-02 Nanobiotix Pharmaceutical compositions, preparation and uses thereof
FI3229776T3 (fi) 2014-11-25 2023-08-15 Curadigm Sas Farmaseuttinen koostumus, joka yhdistää ainakin kaksi erillistä nanopartikkelia ja farmaseuttisen yhdisteen, sen valmistus ja käytöt
KR101729494B1 (ko) 2015-06-29 2017-04-25 제주대학교 산학협력단 6,7-디하이드록시 베르가모틴을 함유한 화장료 조성물

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2996838B2 (ja) * 1993-07-12 2000-01-11 株式会社ポッカコーポレーション 抗菌剤
US5567592A (en) 1994-02-02 1996-10-22 Regents Of The University Of California Screening method for the identification of bioenhancers through the inhibition of P-glycoprotein transport in the gut of a mammal
US5716928A (en) 1995-06-07 1998-02-10 Avmax, Inc. Use of essential oils to increase bioavailability of oral pharmaceutical compounds
US5665386A (en) 1995-06-07 1997-09-09 Avmax, Inc. Use of essential oils to increase bioavailability of oral pharmaceutical compounds
US5916566A (en) * 1995-06-07 1999-06-29 Avmax, Inc. Use of benzoin gum to inhibit P-glycoprotein-mediated resistance of pharmaceutical compounds
US6160006A (en) * 1996-10-18 2000-12-12 Wayne State University 6',7'-dihydroxybergamottin, a cytochrome P450 inhibitor in grapefruit

Also Published As

Publication number Publication date
BR9812131A (pt) 2000-07-18
WO1999008676A1 (en) 1999-02-25
AU8777098A (en) 1999-03-08
US6509371B1 (en) 2003-01-21
DE69819519T2 (de) 2004-09-23
NZ502668A (en) 2001-10-26
EP1007034B1 (en) 2003-11-05
PT1007034E (pt) 2004-03-31
KR100510809B1 (ko) 2005-08-31
EP1007034A1 (en) 2000-06-14
KR20010023034A (ko) 2001-03-26
DE69819519D1 (de) 2003-12-11
ATE253357T1 (de) 2003-11-15
CA2291233A1 (en) 1999-02-25
JP2001515035A (ja) 2001-09-18
ES2209184T3 (es) 2004-06-16
DK1007034T3 (da) 2004-03-22
AU747051B2 (en) 2002-05-09
CA2291233C (en) 2006-10-10

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