ZA985278B - Compounds with growth hormone releasing properties - Google Patents

Compounds with growth hormone releasing properties

Info

Publication number
ZA985278B
ZA985278B ZA985278A ZA985278A ZA985278B ZA 985278 B ZA985278 B ZA 985278B ZA 985278 A ZA985278 A ZA 985278A ZA 985278 A ZA985278 A ZA 985278A ZA 985278 B ZA985278 B ZA 985278B
Authority
ZA
South Africa
Prior art keywords
compounds
growth hormone
hormone releasing
releasing properties
properties
Prior art date
Application number
ZA985278A
Inventor
Thomas Kruse Hansen
Jesper Lau
Bernd Peschke
Michael Ankersen
Kjeld Madsen
Nils Langeland Johansen
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of ZA985278B publication Critical patent/ZA985278B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0207—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)4-C(=0), e.g. 'isosters', replacing two amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0827—Tripeptides containing heteroatoms different from O, S, or N
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA985278A 1997-06-20 1998-06-18 Compounds with growth hormone releasing properties ZA985278B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK72597 1997-06-20

Publications (1)

Publication Number Publication Date
ZA985278B true ZA985278B (en) 1999-01-19

Family

ID=8096826

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA985278A ZA985278B (en) 1997-06-20 1998-06-18 Compounds with growth hormone releasing properties

Country Status (5)

Country Link
EP (1) EP1005484A1 (en)
JP (1) JP4116097B2 (en)
AU (1) AU7906998A (en)
WO (1) WO1998058950A1 (en)
ZA (1) ZA985278B (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1047709B1 (en) * 1998-01-16 2004-11-03 Novo Nordisk A/S Compounds with growth hormone releasing properties
US6083908A (en) * 1998-01-16 2000-07-04 Novo Nordisk A/S Compounds with growth hormone releasing properties
MY153569A (en) 1998-01-20 2015-02-27 Mitsubishi Tanabe Pharma Corp Inhibitors of ?4 mediated cell adhesion
US6919315B1 (en) 1998-06-30 2005-07-19 Novo Nordisk A/S Compounds with growth hormone releasing properties
AU771644B2 (en) * 1998-06-30 2004-04-01 Helsinn Healthcare Sa Compounds with growth hormone releasing properties
WO2000048623A1 (en) 1999-02-18 2000-08-24 Kaken Pharmaceutical Co., Ltd. Novel amide derivatives as growth hormone secretagogues
AU772752B2 (en) * 1999-07-26 2004-05-06 Baylor College Of Medicine Super-active porcine growth hormone releasing hormone analog
DE60140285D1 (en) 2000-05-31 2009-12-10 Pfizer Prod Inc Use of growth hormone secretagogues to promote the mobility of the digestive tract
CN1703395A (en) 2002-08-09 2005-11-30 特兰斯泰克制药公司 Aryl and heteroaryl compounds and methods to modulate coagulation
US7476653B2 (en) 2003-06-18 2009-01-13 Tranzyme Pharma, Inc. Macrocyclic modulators of the ghrelin receptor
US7208601B2 (en) 2003-08-08 2007-04-24 Mjalli Adnan M M Aryl and heteroaryl compounds, compositions, and methods of use
US7459472B2 (en) 2003-08-08 2008-12-02 Transtech Pharma, Inc. Aryl and heteroaryl compounds, compositions, and methods of use
CU23558A1 (en) 2006-02-28 2010-07-20 Ct Ingenieria Genetica Biotech COMPOUNDS ANALOG TO THE PEPTIDIC SECRETAGOGS OF THE GROWTH HORMONE
EA200901077A1 (en) 2007-02-09 2010-04-30 Транзим Фарма, Инк. MACRO CYCLIC MODULATORS OF THE GREEL RECEPTOR AND THEIR APPLICATION
US9119832B2 (en) 2014-02-05 2015-09-01 The Regents Of The University Of California Methods of treating mild brain injury
US20170121385A1 (en) 2015-10-28 2017-05-04 Oxeia Biopharmaceuticals, Inc. Methods of treating neurodegenerative conditions

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1175810A (en) 1979-03-30 1984-10-09 Frank A. Momany Synthetic peptides having pituitary growth hormone releasing activity
BR8208035A (en) 1981-12-28 1983-11-22 Beckman Instruments Inc SYNTHETIC PEPTIDEOS HAVING HORMONE RELEASE ACTIVITY FROM PITUITARY GROWTH
US4839344A (en) 1987-06-12 1989-06-13 Eastman Kodak Company Polypeptide compounds having growth hormone releasing activity
US4817283A (en) 1987-08-21 1989-04-04 Amp Incorporated Method of forming a modular plug coupler
EP0400051B1 (en) 1988-01-28 1995-05-10 Polygen Holding Corporation Polypeptide compounds having growth hormone releasing activity
JPH03504245A (en) 1988-05-11 1991-09-19 ポリゲン　ホールディング　コーポレイション Polypeptide compounds with growth hormone-releasing activity
IT1240643B (en) 1990-05-11 1993-12-17 Mediolanum Farmaceutici Spa BIOLOGICALLY ACTIVE PEPTIDES CONTAINING IN 2-ALCHYL TRIPTOFANE CHAIN
IL98910A0 (en) 1990-07-24 1992-07-15 Polygen Holding Corp Polypeptide compounds having growth hormone releasing activity and pharmaceutical compositions containing them
US5663146A (en) 1991-08-22 1997-09-02 Administrators Of The Tulane Educational Fund Polypeptide analogues having growth hormone releasing activity
WO1995014666A1 (en) 1993-11-24 1995-06-01 Merck & Co., Inc. Indolyl group containing compounds and the use thereof to promote the release of growth hormone(s)
SK281963B6 (en) 1993-12-23 2001-09-11 Novo Nordisk A/S Compounds with growth hormone releasing properties, pharmaceutical compositions comprising them and their use
DE69427650T2 (en) 1993-12-23 2001-11-22 Novo Nordisk A/S, Bagsvaerd CONNECTIONS WITH GROWTH HORMONE RELEASING PROPERTIES
US5798337A (en) * 1994-11-16 1998-08-25 Genentech, Inc. Low molecular weight peptidomimetic growth hormone secretagogues
UA55381C2 (en) 1995-01-27 2003-04-15 Ново Нордіск А/С Derivatives of peptide (variants) able to release a growth hormone, a pharmaceutical composition (variants), a method for stimulating the release of growth hormone from hypophysis, methods for increasing speeds and rates of growth and milk and wool production, a method for treating malaises
PL186520B1 (en) 1995-06-22 2004-01-30 Novo Nordisk As Compunds exhibiting growth hormone liberating properties
CZ195098A3 (en) 1995-12-22 1998-10-14 Novo Nordisk A/S Growth hormone releasing compounds
DE69713109T2 (en) * 1996-07-22 2003-01-02 Novo Nordisk A/S, Bagsvaerd CONNECTIONS WITH GROWTH HORMONE RELEASING PROPERTIES

Also Published As

Publication number Publication date
EP1005484A1 (en) 2000-06-07
WO1998058950A1 (en) 1998-12-30
AU7906998A (en) 1999-01-04
JP4116097B2 (en) 2008-07-09
JP2002505677A (en) 2002-02-19

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