ZA973018B - Endothelin antagonists with ether-linked groups. - Google Patents

Endothelin antagonists with ether-linked groups.

Info

Publication number
ZA973018B
ZA973018B ZA9703018A ZA973018A ZA973018B ZA 973018 B ZA973018 B ZA 973018B ZA 9703018 A ZA9703018 A ZA 9703018A ZA 973018 A ZA973018 A ZA 973018A ZA 973018 B ZA973018 B ZA 973018B
Authority
ZA
South Africa
Prior art keywords
ether
endothelin antagonists
linked groups
linked
groups
Prior art date
Application number
ZA9703018A
Other languages
English (en)
Inventor
Xue-Min Cheng
William Chester Patt
Annette Marian Doherty
Joseph Thomas Repine
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of ZA973018B publication Critical patent/ZA973018B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/60—Two oxygen atoms, e.g. succinic anhydride

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA9703018A 1996-04-10 1997-04-09 Endothelin antagonists with ether-linked groups. ZA973018B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US1523896P 1996-04-10 1996-04-10

Publications (1)

Publication Number Publication Date
ZA973018B true ZA973018B (en) 1997-11-04

Family

ID=21770289

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9703018A ZA973018B (en) 1996-04-10 1997-04-09 Endothelin antagonists with ether-linked groups.

Country Status (4)

Country Link
US (1) US6133263A (fr)
AU (1) AU1991197A (fr)
WO (1) WO1997037986A1 (fr)
ZA (1) ZA973018B (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5962490A (en) 1987-09-25 1999-10-05 Texas Biotechnology Corporation Thienyl-, furyl- and pyrrolyl-sulfonamides and derivatives thereof that modulate the activity of endothelin
US6613804B2 (en) 1993-05-20 2003-09-02 Encysive Pharmaceuticals, Inc. Biphenylsulfonamides and derivatives thereof that modulate the activity of endothelin
US6541498B2 (en) 1993-05-20 2003-04-01 Texas Biotechnology Benzenesulfonamides and the use thereof to modulate the activity of endothelin
US6342610B2 (en) 1993-05-20 2002-01-29 Texas Biotechnology Corp. N-aryl thienyl-, furyl-, and pyrrolyl-sulfonamides and derivatives thereof that modulate the activity of endothelin
US6376523B1 (en) 1994-05-20 2002-04-23 Texas Biotechnology Corporation Benzenesulfonamides and the use thereof to modulate the activity of endothelin
US5977117A (en) 1996-01-05 1999-11-02 Texas Biotechnology Corporation Substituted phenyl compounds and derivatives thereof that modulate the activity of endothelin
US5804585A (en) 1996-04-15 1998-09-08 Texas Biotechnology Corporation Thieno-pyridine sulfonamides derivatives thereof and related compounds that modulate the activity of endothelin
TR200101905T2 (tr) 1997-04-28 2002-06-21 Texas Biotechnology Corporation Endotelin ile ilgili hastalıkların tedavisinde kullanılan sülfanoamidler.
US5783705A (en) 1997-04-28 1998-07-21 Texas Biotechnology Corporation Process of preparing alkali metal salys of hydrophobic sulfonamides
ATE286051T1 (de) 1999-12-31 2005-01-15 Encysive Pharmaceuticals Inc Sulfonamide und ihre derivate, die die aktivität des endothelins modulieren
US20030176356A1 (en) * 2001-04-24 2003-09-18 University Of North Texas Health Science Center Endothelin antagonists and endothelin-converting enzyme inhibitors for the treatment of glaucoma
CN106565644A (zh) * 2016-10-28 2017-04-19 上海大学 3‑烷基‑5‑羟基‑4‑芳基呋喃酮衍生物及其制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2032559C (fr) * 1989-12-28 2001-11-06 Kiyofumi Ishikawa Pentapeptides cycliques antagonistes de l'endotheline
SK20396A3 (en) * 1993-08-19 1997-03-05 Warner Lambert Co Substituted 2(5h)furanone, 2(5h)thiophenone or 2(5h)pyrrolone derivatives and pharmaceutical compositions on their base
WO1997002265A1 (fr) * 1995-07-06 1997-01-23 Warner-Lambert Company ANTAGONISTES DE l'ENDOTHELINE BUTENOLIDIQUE
US5998468A (en) * 1995-08-24 1999-12-07 Warner-Lambert Company Furanone endothelin antagonists

Also Published As

Publication number Publication date
US6133263A (en) 2000-10-17
AU1991197A (en) 1997-10-29
WO1997037986A1 (fr) 1997-10-16

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