ZA9711271B - Novel heterocyclic substituted pyrrolidine amide derivatives. - Google Patents

Novel heterocyclic substituted pyrrolidine amide derivatives.

Info

Publication number
ZA9711271B
ZA9711271B ZA9711271A ZA9711271A ZA9711271B ZA 9711271 B ZA9711271 B ZA 9711271B ZA 9711271 A ZA9711271 A ZA 9711271A ZA 9711271 A ZA9711271 A ZA 9711271A ZA 9711271 B ZA9711271 B ZA 9711271B
Authority
ZA
South Africa
Prior art keywords
amide derivatives
heterocyclic substituted
novel heterocyclic
substituted pyrrolidine
pyrrolidine amide
Prior art date
Application number
ZA9711271A
Other languages
English (en)
Inventor
Timothy P Burkholder
George D Maynard
Elizabeth M Kudlacz
Original Assignee
Hoechst Marion Roussel Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Marion Roussel Inc filed Critical Hoechst Marion Roussel Inc
Publication of ZA9711271B publication Critical patent/ZA9711271B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/14Antitussive agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
ZA9711271A 1996-12-19 1997-12-15 Novel heterocyclic substituted pyrrolidine amide derivatives. ZA9711271B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US76981296A 1996-12-19 1996-12-19

Publications (1)

Publication Number Publication Date
ZA9711271B true ZA9711271B (en) 1998-06-19

Family

ID=25086573

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9711271A ZA9711271B (en) 1996-12-19 1997-12-15 Novel heterocyclic substituted pyrrolidine amide derivatives.

Country Status (21)

Country Link
EP (1) EP0946548B1 (xx)
JP (1) JP4195512B2 (xx)
KR (1) KR100514263B1 (xx)
CN (1) CN1119344C (xx)
AR (1) AR009665A1 (xx)
AT (1) ATE214063T1 (xx)
AU (1) AU723966B2 (xx)
BR (1) BR9714057A (xx)
CA (1) CA2275527C (xx)
DE (1) DE69710921T2 (xx)
DK (1) DK0946548T3 (xx)
ES (1) ES2169881T3 (xx)
HK (1) HK1020947A1 (xx)
HU (1) HUP0000315A3 (xx)
IL (1) IL130223A (xx)
NO (1) NO317760B1 (xx)
NZ (1) NZ335975A (xx)
PT (1) PT946548E (xx)
TW (1) TW486477B (xx)
WO (1) WO1998027086A1 (xx)
ZA (1) ZA9711271B (xx)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ID29137A (id) * 1998-07-27 2001-08-02 Schering Corp Ligan-ligan afinitas tinggi untuk reseptor nosiseptin orl-1
IL158990A0 (en) * 2001-07-20 2004-05-12 Pfizer Prod Inc Use of nk-1 receptor antagonists to modify unwanted behavior in dogs, cats and horses
ATE519738T1 (de) 2007-08-22 2011-08-15 Hoffmann La Roche Pyrrolidinarylether als nk3-rezeptorantagonisten
AU2019373306A1 (en) 2018-10-29 2021-04-08 Boehringer Ingelheim International Gmbh Pyridinyl sulfonamide derivatives, pharmaceutical compositions and uses thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2676055B1 (fr) * 1991-05-03 1993-09-03 Sanofi Elf Composes polycycliques amines et leurs enantiomeres, procede pour leur preparation et compositions pharmaceutiques les contenant.
WO1994026735A1 (en) * 1993-05-06 1994-11-24 Merrell Dow Pharmaceuticals Inc. Substituted pyrrolidin-3-yl-alkyl-piperidines useful as tachykinin antagonists
WO1997019074A1 (en) * 1995-11-17 1997-05-29 Hoechst Marion Roussel, Inc. Substituted 4-(1h-benzimidazol-2-yl-amino)piperidines useful for the treatment of allergic diseases

Also Published As

Publication number Publication date
EP0946548A1 (en) 1999-10-06
IL130223A (en) 2005-09-25
NZ335975A (en) 2000-11-24
DE69710921T2 (de) 2002-09-19
NO993013L (no) 1999-08-18
BR9714057A (pt) 2000-05-09
IL130223A0 (en) 2000-06-01
JP2001506650A (ja) 2001-05-22
HK1020947A1 (en) 2000-05-26
HUP0000315A3 (en) 2002-01-28
NO993013D0 (no) 1999-06-18
CA2275527C (en) 2003-09-23
ES2169881T3 (es) 2002-07-16
DE69710921D1 (de) 2002-04-11
HUP0000315A2 (hu) 2001-04-28
KR100514263B1 (ko) 2005-09-15
WO1998027086A1 (en) 1998-06-25
ATE214063T1 (de) 2002-03-15
JP4195512B2 (ja) 2008-12-10
AU5160798A (en) 1998-07-15
CN1241185A (zh) 2000-01-12
DK0946548T3 (da) 2002-06-24
PT946548E (pt) 2002-06-28
NO317760B1 (no) 2004-12-13
AR009665A1 (es) 2000-04-26
EP0946548B1 (en) 2002-03-06
CN1119344C (zh) 2003-08-27
TW486477B (en) 2002-05-11
AU723966B2 (en) 2000-09-07
CA2275527A1 (en) 1998-06-25
KR20000057668A (ko) 2000-09-25

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