ZA968897B - Novel chemokine for mobilizing stem cells - Google Patents

Novel chemokine for mobilizing stem cells

Info

Publication number
ZA968897B
ZA968897B ZA968897A ZA968897A ZA968897B ZA 968897 B ZA968897 B ZA 968897B ZA 968897 A ZA968897 A ZA 968897A ZA 968897 A ZA968897 A ZA 968897A ZA 968897 B ZA968897 B ZA 968897B
Authority
ZA
South Africa
Prior art keywords
stem cells
novel chemokine
mobilizing stem
mobilizing
chemokine
Prior art date
Application number
ZA968897A
Other languages
English (en)
Inventor
John R White
Louis Pelus
Haodong Li
Brendt L Kreider
Original Assignee
Smithkline Beecham Corp
Human Genome Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp, Human Genome Sciences Inc filed Critical Smithkline Beecham Corp
Publication of ZA968897B publication Critical patent/ZA968897B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/521—Chemokines
    • C07K14/523—Beta-chemokines, e.g. RANTES, I-309/TCA-3, MIP-1alpha, MIP-1beta/ACT-2/LD78/SCIF, MCP-1/MCAF, MCP-2, MCP-3, LDCF-1, LDCF-2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
ZA968897A 1995-10-24 1996-10-23 Novel chemokine for mobilizing stem cells ZA968897B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US605195P 1995-10-24 1995-10-24

Publications (1)

Publication Number Publication Date
ZA968897B true ZA968897B (en) 1998-07-14

Family

ID=21719050

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA968897A ZA968897B (en) 1995-10-24 1996-10-23 Novel chemokine for mobilizing stem cells

Country Status (8)

Country Link
EP (1) EP0871664B1 (da)
JP (1) JP2001519757A (da)
AU (1) AU7468896A (da)
CA (1) CA2235360A1 (da)
DE (1) DE69631253T2 (da)
DK (1) DK0871664T3 (da)
WO (1) WO1997015594A1 (da)
ZA (1) ZA968897B (da)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6001606A (en) * 1994-03-08 1999-12-14 Human Genome Sciences, Inc. Polynucleotides encoding myeloid progenitor inhibitory factor-1 (MPIF-1) and polypeptides encoded thereby
US6811773B1 (en) 1993-12-22 2004-11-02 Human Genome Sciences, Inc. Human monocyte colony inhibitory factor (M-CIF) polypeptides
US6451562B1 (en) 1993-12-22 2002-09-17 Human Genome Sciences, Inc. Polypeptides encoding myeloid progenitor inhibitory factor-1 (MPIF-1) polynucleotides
US6488925B2 (en) 1993-12-22 2002-12-03 Human Genome Sciences, Inc. Macrophage inflammatory protein-4 (MIP-4) polypeptides
US6495129B1 (en) 1994-03-08 2002-12-17 Human Genome Sciences, Inc. Methods of inhibiting hematopoietic stem cells using human myeloid progenitor inhibitory factor-1 (MPIF-1) (Ckbeta-8/MIP-3)
US5866373A (en) * 1995-04-21 1999-02-02 Human Genome Sciences, Inc. Polynucleotide encoding a human chemotactic protein
US6075124A (en) * 1994-05-16 2000-06-13 Human Genome Sciences, Inc. Human chemotactin protein
US6100389A (en) * 1995-04-21 2000-08-08 Human Genome Sciences, Inc. Polynucleotides encoding a human chemotactic protein
US6391589B1 (en) 1994-08-23 2002-05-21 Human Genome Sciences, Inc. Human chemokine beta-10 mutant polypeptides
US5981230A (en) * 1994-08-23 1999-11-09 Human Genome Sciences, Inc. Polynucleotide encoding chemokine β-4
US6174995B1 (en) 1994-08-23 2001-01-16 Haodong Li Human chemokines, CKβ4 and CKβ10/MCP-4
US6458349B1 (en) 1995-06-02 2002-10-01 Human Genome Sciences, Inc. Chemokine β-4 polypeptides
US6139832A (en) 1995-02-08 2000-10-31 Human Genome Sciences, Inc. Leukocyte adhesion inhibitor-1 (LAI-1) Polypeptides
AU711573B2 (en) * 1995-09-29 1999-10-14 Smithkline Beecham Corporation Short forms of chemokine beta-8
US6290948B1 (en) * 1996-05-14 2001-09-18 Smithkline Beecham Corporation Method of treating sepsis and ARDS using chamohine beta-10
US5912327A (en) * 1996-09-30 1999-06-15 Human Genome Sciences, Inc. Method of purifying chemokines from inclusion bodies
CN1239510A (zh) * 1996-09-30 1999-12-22 人类基因组科学公司 用髓先祖抑制因子－1、单核细胞集落抑制因子和巨噬细胞抑制因子－4治疗疾病的组合物和方法
AU4804697A (en) * 1996-10-04 1998-04-24 Human Genome Sciences, Inc. Therapeutic compositions and methods for treating disease states with leukocyte adhesion inhibitor-1 (lai-1), and chemokine beta-11 (ckbeta-11)
WO1998024908A1 (en) * 1996-12-05 1998-06-11 Human Genome Sciences, Inc. Human chemokine beta-13
WO1998026071A1 (fr) * 1996-12-13 1998-06-18 Shionogi & Co., Ltd. Chemokine cc humaine elc
US6632425B1 (en) 1997-03-20 2003-10-14 Human Genome Sciences, Inc. Chemokine compositions
US6028169A (en) * 1997-03-31 2000-02-22 Human Genome Sciences, Inc. Chemokine β-6 antagonists
US6562800B1 (en) * 1998-10-30 2003-05-13 University Of Southern California Use of immunopotentiating sequences for inducing immune response
WO2000028035A1 (en) * 1998-11-10 2000-05-18 Human Genome Sciences Inc. CHEMOKINE β-7
CA2359853A1 (en) * 1999-01-08 2000-07-13 Human Genome Sciences, Inc. Human chemokine beta-10 mutant polypeptides
AU2505601A (en) * 1999-11-15 2001-05-30 Wolf-Georg Forssmann Novel use of hcc-2
AU2003225237A1 (en) 2002-05-01 2003-11-17 Human Genome Sciences, Inc. Antibodies that specifically bind to chemokine beta-4
PE20140633A1 (es) 2010-11-19 2014-05-30 Eisai Randd Man Co Ltd Anticuerpos neutralizadores anti-ccl20

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2214484T3 (es) * 1993-12-22 2004-09-16 Human Genome Sciences, Inc. Proteinas inflamatorias de macrofagos mip-3, mip-4 y mip-1 gamma.
ATE218616T1 (de) * 1993-12-24 2002-06-15 Forssmann Wolf Georg Humanes zirkulierendes cytokin cc-1

Also Published As

Publication number Publication date
JP2001519757A (ja) 2001-10-23
WO1997015594A1 (en) 1997-05-01
DK0871664T3 (da) 2004-04-26
AU7468896A (en) 1997-05-15
EP0871664A4 (en) 2000-07-05
EP0871664B1 (en) 2004-01-02
DE69631253D1 (de) 2004-02-05
EP0871664A1 (en) 1998-10-21
DE69631253T2 (de) 2004-11-18
CA2235360A1 (en) 1997-05-01

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