ZA966154B - Aminophenylphosphonic acid compounds process for preparing them and pharmaceutical compositions containing them - Google Patents

Aminophenylphosphonic acid compounds process for preparing them and pharmaceutical compositions containing them

Info

Publication number
ZA966154B
ZA966154B ZA966154A ZA966154A ZA966154B ZA 966154 B ZA966154 B ZA 966154B ZA 966154 A ZA966154 A ZA 966154A ZA 966154 A ZA966154 A ZA 966154A ZA 966154 B ZA966154 B ZA 966154B
Authority
ZA
South Africa
Prior art keywords
preparing
pharmaceutical compositions
compositions containing
acid compounds
compounds process
Prior art date
Application number
ZA966154A
Other languages
English (en)
Inventor
Alex Cordi
Patrice Desos
Angela D Morris
Ghanem Atassi
Original Assignee
Adir
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adir filed Critical Adir
Publication of ZA966154B publication Critical patent/ZA966154B/xx

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6553Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having sulfur atoms, with or without selenium or tellurium atoms, as the only ring hetero atoms
    • C07F9/655345Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having sulfur atoms, with or without selenium or tellurium atoms, as the only ring hetero atoms the sulfur atom being part of a five-membered ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3834Aromatic acids (P-C aromatic linkage)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3882Arylalkanephosphonic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40Esters thereof
    • C07F9/4003Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4021Esters of aromatic acids (P-C aromatic linkage)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/572Five-membered rings
    • C07F9/5728Five-membered rings condensed with carbocyclic rings or carbocyclic ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/655Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
    • C07F9/65515Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a five-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA966154A 1995-07-21 1996-07-19 Aminophenylphosphonic acid compounds process for preparing them and pharmaceutical compositions containing them ZA966154B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9508821A FR2736914B1 (fr) 1995-07-21 1995-07-21 Nouveaux derives d'acide aminophenylphosphonique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
ZA966154B true ZA966154B (en) 1997-01-23

Family

ID=9481204

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA966154A ZA966154B (en) 1995-07-21 1996-07-19 Aminophenylphosphonic acid compounds process for preparing them and pharmaceutical compositions containing them

Country Status (10)

Country Link
US (1) US5670493A (xx)
EP (1) EP0754693A3 (xx)
JP (1) JPH0952895A (xx)
CN (1) CN1063182C (xx)
AU (1) AU703822B2 (xx)
CA (1) CA2180621C (xx)
FR (1) FR2736914B1 (xx)
NO (1) NO308004B1 (xx)
NZ (1) NZ299033A (xx)
ZA (1) ZA966154B (xx)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2758562B1 (fr) * 1997-01-20 1999-02-19 Adir Nouveaux derives d'acides mixtes aminobenzyliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
US6096730A (en) * 1997-07-24 2000-08-01 University Of Kentucky Research Foundation Phosphonated agents and their antiangiogenic and antitumorigenic use
EP1017389A1 (en) 1997-08-25 2000-07-12 Harold Brem Prevention of adhesions and excessive scar formation using angiogenesis inhibitors
US6673843B2 (en) * 1999-06-30 2004-01-06 Emory University Curcumin and curcuminoid inhibition of angiogenesis
TWI262185B (en) * 1999-10-01 2006-09-21 Eisai Co Ltd Carboxylic acid derivatives having anti-hyperglycemia and anti-hyperlipemia action, and pharmaceutical composition containing the derivatives
DE50103312D1 (de) * 2001-02-23 2004-09-23 Sirs Lab Gmbh Furanfettsäuren zur Steigerung der Effizienz der Zytostatikatherapie und/oder Bestrahlungstherapie
US20060229239A9 (en) * 2002-03-08 2006-10-12 Mamoru Shoji Novel curcuminoid-factor VIIa constructs as suppressors of tumor growth and angiogenesis
ES2463490T3 (es) * 2006-08-23 2014-05-28 Novartis Ag Amidas como inhibidores de la esfingomielina
US20100132796A1 (en) * 2008-11-28 2010-06-03 Samsung Electro-Mechanics Co., Ltd. Dye compound for dye-sensitized solar cells, dye-sensitized photoelectric converter and dye-sensitized solar cells

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU547451A1 (ru) * 1975-07-24 1977-02-25 Военная Краснознаменная Академия Химической Защиты Имени Маршала Советского Союза С.К.Тимошенко Способ получени -фенил- или -бензиламинометилфосфоновых кислот
EP0093081B1 (de) * 1982-04-23 1986-03-19 Ciba-Geigy Ag Herbizide und pflanzenwuchsregulierende Mittel
US4591582A (en) * 1984-04-17 1986-05-27 Research Corporation Organophosphorus compounds useful as anticonvulsant agents
WO1990015816A1 (en) * 1989-06-16 1990-12-27 The Upjohn Company Suramin type compounds and angiostatic steroids to inhibit angiogenesis
GB9403909D0 (en) * 1994-03-01 1994-04-20 Erba Carlo Spa Ureido derivatives of naphthalenephosphonic acids and process for their preparation
US5734081A (en) * 1994-08-05 1998-03-31 Warner-Lambert Company Arylthio compounds

Also Published As

Publication number Publication date
CN1063182C (zh) 2001-03-14
EP0754693A2 (fr) 1997-01-22
NO963024D0 (no) 1996-07-19
NO963024L (no) 1997-01-22
AU703822B2 (en) 1999-04-01
US5670493A (en) 1997-09-23
NO308004B1 (no) 2000-07-03
FR2736914A1 (fr) 1997-01-24
CN1145908A (zh) 1997-03-26
CA2180621C (fr) 2000-02-15
FR2736914B1 (fr) 1997-08-22
NZ299033A (en) 1997-07-27
EP0754693A3 (fr) 1997-11-05
AU6058496A (en) 1997-01-30
JPH0952895A (ja) 1997-02-25
CA2180621A1 (fr) 1997-01-22

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