ZA959517B - Leutherobin and analogs thereof - Google Patents

Leutherobin and analogs thereof

Info

Publication number
ZA959517B
ZA959517B ZA959517A ZA959517A ZA959517B ZA 959517 B ZA959517 B ZA 959517B ZA 959517 A ZA959517 A ZA 959517A ZA 959517 A ZA959517 A ZA 959517A ZA 959517 B ZA959517 B ZA 959517B
Authority
ZA
South Africa
Prior art keywords
leutherobin
analogs
Prior art date
Application number
ZA959517A
Other languages
English (en)
Inventor
William H Fenical
Paul R Jensen
Thomas Lindel
Original Assignee
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ California filed Critical Univ California
Publication of ZA959517B publication Critical patent/ZA959517B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/7056—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Plant Substances (AREA)
ZA959517A 1994-11-09 1995-11-09 Leutherobin and analogs thereof ZA959517B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/336,518 US5473057A (en) 1994-11-09 1994-11-09 Eleutherobin and analogs thereof

Publications (1)

Publication Number Publication Date
ZA959517B true ZA959517B (en) 1996-06-20

Family

ID=23316461

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA959517A ZA959517B (en) 1994-11-09 1995-11-09 Leutherobin and analogs thereof

Country Status (16)

Country Link
US (1) US5473057A (no)
EP (1) EP0790769A4 (no)
JP (1) JPH10508611A (no)
KR (1) KR970706732A (no)
AR (1) AR002247A1 (no)
AU (1) AU688177B2 (no)
BR (1) BR9510357A (no)
CZ (1) CZ288170B6 (no)
HU (1) HUT77882A (no)
IL (1) IL116190A (no)
NO (1) NO306347B1 (no)
NZ (1) NZ296728A (no)
PL (1) PL181693B1 (no)
RU (1) RU2146089C1 (no)
WO (1) WO1996014745A1 (no)
ZA (1) ZA959517B (no)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5965718A (en) * 1997-10-24 1999-10-12 The Scripps Research Institute Analogs of sarcodictyin and eleutherobin
US6172205B1 (en) * 1997-12-11 2001-01-09 The Trustees Of Columbia In The City Of New York Synthetic process toward total synthesis of eleutherobin and its analogues and uses thereof
US6833373B1 (en) 1998-12-23 2004-12-21 G.D. Searle & Co. Method of using an integrin antagonist and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia
US6858598B1 (en) 1998-12-23 2005-02-22 G. D. Searle & Co. Method of using a matrix metalloproteinase inhibitor and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia
US6066635A (en) * 1999-03-23 2000-05-23 University Of California, San Diego Avrainvillamide, a cytotoxic marine natural product, and derivatives thereof
CA2290316A1 (en) * 1999-11-24 2001-05-24 The University Of British Columbia Novel source of eleutherobin and related antimitotic diterpenes
US6946283B2 (en) 2001-01-05 2005-09-20 William Marsh Rice University Ginkgo biloba levopimaradiene synthase
US7238514B2 (en) * 2001-01-05 2007-07-03 William Marsh Rice University Diterpene-producing unicellular organism
WO2003000711A1 (en) 2001-06-22 2003-01-03 The University Of British Columbia Antimitotic eleuthesides
EP1883627B1 (en) 2005-05-18 2018-04-18 Pharmascience Inc. Bir domain binding compounds
NZ572836A (en) 2006-05-16 2011-12-22 Pharmascience Inc Iap bir domain binding compounds
SG10201501095WA (en) 2010-02-12 2015-04-29 Pharmascience Inc Iap bir domain binding compounds
US9567643B2 (en) 2013-10-04 2017-02-14 Aptose Biosciences Inc. Compositions and methods for treating cancers

Also Published As

Publication number Publication date
MX9703414A (es) 1997-07-31
CZ139697A3 (en) 1997-09-17
EP0790769A1 (en) 1997-08-27
BR9510357A (pt) 1997-12-23
CZ288170B6 (en) 2001-05-16
NO306347B1 (no) 1999-10-25
PL320089A1 (en) 1997-09-15
EP0790769A4 (en) 1998-10-21
JPH10508611A (ja) 1998-08-25
PL181693B1 (pl) 2001-09-28
NZ296728A (en) 1998-03-25
NO972103L (no) 1997-05-07
WO1996014745A1 (en) 1996-05-23
NO972103D0 (no) 1997-05-07
AR002247A1 (es) 1998-03-11
AU4140996A (en) 1996-06-06
AU688177B2 (en) 1998-03-05
IL116190A (en) 1999-12-22
RU2146089C1 (ru) 2000-03-10
HUT77882A (hu) 1998-09-28
IL116190A0 (en) 1996-01-31
KR970706732A (ko) 1997-12-01
US5473057A (en) 1995-12-05

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