ZA959311B - 5-(aryloxymethyl)oxazolines a process for the preparation thereof and pharmaceutical compositions containing them - Google Patents

5-(aryloxymethyl)oxazolines a process for the preparation thereof and pharmaceutical compositions containing them

Info

Publication number
ZA959311B
ZA959311B ZA959311A ZA959311A ZA959311B ZA 959311 B ZA959311 B ZA 959311B ZA 959311 A ZA959311 A ZA 959311A ZA 959311 A ZA959311 A ZA 959311A ZA 959311 B ZA959311 B ZA 959311B
Authority
ZA
South Africa
Prior art keywords
alkyl
aryloxymethyl
oxazolines
preparation
pharmaceutical compositions
Prior art date
Application number
ZA959311A
Other languages
English (en)
Inventor
Christian Jarry
Isabelle Forfar
Jean-Jacques Bosc
Pierre Renard
Elizabeth Scalbert
Beatrice Guardiola
Original Assignee
Adir
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adir filed Critical Adir
Publication of ZA959311B publication Critical patent/ZA959311B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/28—Nitrogen atoms not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA959311A 1994-11-03 1995-11-03 5-(aryloxymethyl)oxazolines a process for the preparation thereof and pharmaceutical compositions containing them ZA959311B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9413087A FR2726558B1 (fr) 1994-11-03 1994-11-03 Nouvelles 5-(aryloxymethyl) oxazolines, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
ZA959311B true ZA959311B (en) 1996-05-29

Family

ID=9468429

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA959311A ZA959311B (en) 1994-11-03 1995-11-03 5-(aryloxymethyl)oxazolines a process for the preparation thereof and pharmaceutical compositions containing them

Country Status (16)

Country Link
US (1) US5686477A (fi)
EP (1) EP0710658B1 (fi)
JP (1) JP3181211B2 (fi)
CN (1) CN1051545C (fi)
AT (1) ATE206414T1 (fi)
AU (1) AU689320B2 (fi)
CA (1) CA2162106C (fi)
DE (1) DE69523011T2 (fi)
DK (1) DK0710658T3 (fi)
ES (1) ES2165410T3 (fi)
FI (1) FI955238A (fi)
FR (1) FR2726558B1 (fi)
NO (1) NO305755B1 (fi)
NZ (1) NZ280387A (fi)
PT (1) PT710658E (fi)
ZA (1) ZA959311B (fi)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6635668B1 (en) 1998-07-22 2003-10-21 The University Of North Carolina At Chapel Hill Imidazoline receptor binding compounds
WO2002064667A2 (en) * 2001-01-16 2002-08-22 Eastman Chemical Company Color concentrates for polyesters, comprising at least one olefin/(meth) acrylate copolymer
EP1420773A1 (en) * 2001-08-31 2004-05-26 Neurochem (International) Limited Amidine derivatives for treating amyloidosis
CA2487541A1 (en) * 2002-06-19 2003-12-31 Solvay Pharmaceuticals Gmbh Medicament for the treatment of diseases requiring inhibition or a reduction in the activity of ph value-regulating bicarbonate transporter proteins
US7262223B2 (en) * 2004-01-23 2007-08-28 Neurochem (International) Limited Amidine derivatives for treating amyloidosis
MX2009008465A (es) * 2007-02-15 2009-08-20 Hoffmann La Roche Nuevas 2-aminooxazolinas como ligandos de taar1.
JP6694385B2 (ja) 2013-08-09 2020-05-13 アーデリクス，インコーポレーテッド リン酸塩輸送阻害のための化合物及び方法
WO2016105449A1 (en) * 2014-12-22 2016-06-30 Seth Lederman Compounds for use as pain therapeutics

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3052688A (en) * 1962-09-04 Process for the production of
US3110650A (en) * 1961-09-14 1963-11-12 Szabo Hnos Kessler & Cia S R L Synergistic analgesic compositions
US3278382A (en) * 1962-07-23 1966-10-11 Mcneilab Inc 2-amino-5-aryloxazoline compositions and methods of using same
US3161650A (en) * 1963-01-25 1964-12-15 Mcneilab Inc 2-amino-5-aryloxazoline products
US3626067A (en) * 1965-07-01 1971-12-07 Du Pont Substituted oxazolines, useful as pharmaceuticals
US3577428A (en) * 1969-04-14 1971-05-04 Colgate Palmolive Co 2-amino-4-aryloxyalkyl-4-alkyl-2-oxazolines
US3637726A (en) * 1970-04-09 1972-01-25 Dow Chemical Co Substituted-5-((3 4-dihalophenoxy)methyl)-2-oxazoline compounds
US3818028A (en) * 1972-11-01 1974-06-18 Dow Chemical Co Substituted-5-(2,4,6-trihalophenoxy)-methyl)-2-oxazoline compounds
GB8528633D0 (en) * 1985-11-21 1985-12-24 Beecham Group Plc Compounds
FR2645860B1 (fr) * 1989-04-14 1991-07-26 Sarget Lab Nouvelles aryloxymethyl-5 amino-2 oxazolines, syntheses et applications therapeutiques

Also Published As

Publication number Publication date
EP0710658B1 (fr) 2001-10-04
ES2165410T3 (es) 2002-03-16
EP0710658A1 (fr) 1996-05-08
CN1051545C (zh) 2000-04-19
DK0710658T3 (da) 2001-11-26
FR2726558A1 (fr) 1996-05-10
FI955238A (fi) 1996-05-04
US5686477A (en) 1997-11-11
FR2726558B1 (fr) 1996-12-06
NO305755B1 (no) 1999-07-19
FI955238A0 (fi) 1995-11-01
PT710658E (pt) 2002-02-28
ATE206414T1 (de) 2001-10-15
CA2162106C (fr) 2001-04-10
CA2162106A1 (fr) 1996-05-04
NZ280387A (en) 1996-07-26
NO954381L (no) 1996-05-06
DE69523011T2 (de) 2002-07-11
AU3459395A (en) 1996-05-09
JP3181211B2 (ja) 2001-07-03
DE69523011D1 (de) 2001-11-08
CN1129697A (zh) 1996-08-28
AU689320B2 (en) 1998-03-26
JPH08208630A (ja) 1996-08-13
NO954381D0 (no) 1995-11-02

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