ZA958644B - New dipeptide derivatives processes for the preparation thereof and pharmaceutical compositions containing them - Google Patents
New dipeptide derivatives processes for the preparation thereof and pharmaceutical compositions containing themInfo
- Publication number
- ZA958644B ZA958644B ZA958644A ZA958644A ZA958644B ZA 958644 B ZA958644 B ZA 958644B ZA 958644 A ZA958644 A ZA 958644A ZA 958644 A ZA958644 A ZA 958644A ZA 958644 B ZA958644 B ZA 958644B
- Authority
- ZA
- South Africa
- Prior art keywords
- preparation
- pharmaceutical compositions
- compositions containing
- dipeptide derivatives
- derivatives processes
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Hematology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Abstract
Compounds of formula (I) in which R<1> and R<2> are hydroxy or an acyloxy group and R<3> is hydrogen, where R<2> and R<3> together may also signify a valency line. Process for their production from cyanobacteria of the Oscillatoria agardhii genus, and medicaments containing said compounds with a thrombin and trypsin inhibiting action.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4436772A DE4436772A1 (en) | 1994-10-14 | 1994-10-14 | New dipeptide derivative, process for its preparation and medicinal products containing this compound |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA958644B true ZA958644B (en) | 1997-04-14 |
Family
ID=6530791
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA958644A ZA958644B (en) | 1994-10-14 | 1995-10-13 | New dipeptide derivatives processes for the preparation thereof and pharmaceutical compositions containing them |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP0788510B1 (en) |
JP (1) | JPH10507191A (en) |
AT (1) | ATE189229T1 (en) |
AU (1) | AU3804795A (en) |
CA (1) | CA2202379A1 (en) |
DE (2) | DE4436772A1 (en) |
IL (1) | IL115585A (en) |
WO (1) | WO1996011941A1 (en) |
ZA (1) | ZA958644B (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6716869B2 (en) | 2001-12-17 | 2004-04-06 | Pharmacia Corporation | Protease inhibitors of the coagulation cascade isolated from Dysidea sponges |
KR101086259B1 (en) | 2004-12-22 | 2011-11-24 | 에스케이케미칼주식회사 | Composition comprising Oscillatoria agardhii extracts for prevention and treatment of cancer and method of preparing the extracts |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3505555A1 (en) * | 1985-02-18 | 1986-09-11 | Behringwerke Ag, 3550 Marburg | NEW OLIGOPEPTIDYLARGININOL DERIVATIVES AND THEIR HOMOLOGOLOGY, METHOD FOR THE PRODUCTION THEREOF, THE USE THEREOF AND MEANS CONTAINING THEM |
SE9103612D0 (en) * | 1991-12-04 | 1991-12-04 | Astra Ab | NEW PEPTIDE DERIVATIVES |
-
1994
- 1994-10-14 DE DE4436772A patent/DE4436772A1/en not_active Withdrawn
-
1995
- 1995-10-10 EP EP95935923A patent/EP0788510B1/en not_active Expired - Lifetime
- 1995-10-10 AT AT95935923T patent/ATE189229T1/en not_active IP Right Cessation
- 1995-10-10 DE DE59507710T patent/DE59507710D1/en not_active Expired - Fee Related
- 1995-10-10 CA CA002202379A patent/CA2202379A1/en not_active Abandoned
- 1995-10-10 WO PCT/EP1995/003982 patent/WO1996011941A1/en active IP Right Grant
- 1995-10-10 JP JP8512919A patent/JPH10507191A/en active Pending
- 1995-10-10 AU AU38047/95A patent/AU3804795A/en not_active Abandoned
- 1995-10-12 IL IL11558595A patent/IL115585A/en not_active IP Right Cessation
- 1995-10-13 ZA ZA958644A patent/ZA958644B/en unknown
Also Published As
Publication number | Publication date |
---|---|
AU3804795A (en) | 1996-05-06 |
WO1996011941A1 (en) | 1996-04-25 |
IL115585A (en) | 1999-09-22 |
EP0788510B1 (en) | 2000-01-26 |
DE59507710D1 (en) | 2000-03-02 |
DE4436772A1 (en) | 1996-04-18 |
CA2202379A1 (en) | 1996-04-25 |
JPH10507191A (en) | 1998-07-14 |
ATE189229T1 (en) | 2000-02-15 |
IL115585A0 (en) | 1996-01-19 |
EP0788510A1 (en) | 1997-08-13 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MX9706069A (en) | Novel dipeptide amidines as thrombin inhibitors. | |
MX9604020A (en) | Arylalkyldiazinones. | |
IL117805A0 (en) | Carbonyl piperazinyl and piperidinyl compounds | |
GEP20032869B (en) | Alpha -Ketoamide Inhibitors of 20S Proteasome, Pharmaceutical Preparations Containing the Same and Methods for Treatment | |
MY106280A (en) | Novel benzopyrido piperidine, piperidylidene and piperazine compounds, compositions, methods of manufacture and methods of use. | |
HU9401443D0 (en) | Tetrazolyl bile acid derivatives, process for producing them and pharmaceutical compositions containing them | |
IL112622A (en) | Iminoalkylamino or aminoalkylideneamino camptothecin derivatives, process for their preparation and pharmaceutical compositions containing them | |
AP9701041A0 (en) | Pyridylpyrrole compounds. | |
CA2019404A1 (en) | 11 beta-aryl-4-estrenes, process for their production as well as their use as pharmaceutical agents | |
IL117091A0 (en) | Methylphenyloxazolidinone derivatives pharmaceutical compositions containing the same and processes for the preparation thereof | |
MX9503529A (en) | Glycinamide derivatives, process for their preparation and medicaments containing them. | |
EP0590271A3 (en) | 17-aryl and 17-heterocyclyl-14beta-5alpha-androstane, androstene and androstadiene derivatives active on the cardiovascular system, processes for their preparation and pharmaceutical compositions containing same | |
MX9702666A (en) | New peptides with immunomodulatory effects. | |
AU1306795A (en) | Anticonvulsant pseudofructopyranose sulfamates | |
MX9803672A (en) | New phenylamidine derivatives, a process for preparing the same and their use as medicaments. | |
MY114282A (en) | Anthracycline derivatives | |
ZA958644B (en) | New dipeptide derivatives processes for the preparation thereof and pharmaceutical compositions containing them | |
MY114693A (en) | Substituted benzenesulfonylureas and thioureas,processes for their preparation,their use for the production of pharmaceutical preparations, and pharmaceutical preparation containing them | |
AU2067592A (en) | New n-(isoquinolin-5-ylsulphonyl)azacycloalkanes, process for the preparation thereof, and pharmaceutical compositions containing them | |
MY115795A (en) | Substituted benzenesulfonylureas and -thioureas, processes for their preparation and use of pharmaceutical preparations based on these compounds, and medicaments containing them | |
AU6970394A (en) | Desoxyazaphospholipid derivatives having inhibiting activity on phospholipase a2 | |
IL134194A0 (en) | Streptogramines, their preparation and compositions containing them | |
TW344650B (en) | Fungicidal compositions and the process for the preparation thereof | |
AU1192097A (en) | 3-aminoethyl-n-amidino-2,5-dihydropyrrole derivatives having arginine mimetic properties | |
AU4154993A (en) | New peptide compounds active in cell adhesion processes, a process for the preparation thereof, and pharmaceutical compositions containing them |