AU3804795A - Dipeptide derivatives, process for producing them and medicaments containing these compounds - Google Patents

Dipeptide derivatives, process for producing them and medicaments containing these compounds

Info

Publication number
AU3804795A
AU3804795A AU38047/95A AU3804795A AU3804795A AU 3804795 A AU3804795 A AU 3804795A AU 38047/95 A AU38047/95 A AU 38047/95A AU 3804795 A AU3804795 A AU 3804795A AU 3804795 A AU3804795 A AU 3804795A
Authority
AU
Australia
Prior art keywords
compounds
medicaments containing
producing
dipeptide derivatives
dipeptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU38047/95A
Inventor
Silvia Konetschny-Rapp
Hans-Willi Krell
Ulrich Martin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Publication of AU3804795A publication Critical patent/AU3804795A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Compounds of formula (I) in which R<1> and R<2> are hydroxy or an acyloxy group and R<3> is hydrogen, where R<2> and R<3> together may also signify a valency line. Process for their production from cyanobacteria of the Oscillatoria agardhii genus, and medicaments containing said compounds with a thrombin and trypsin inhibiting action.
AU38047/95A 1994-10-14 1995-10-10 Dipeptide derivatives, process for producing them and medicaments containing these compounds Abandoned AU3804795A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE4436772A DE4436772A1 (en) 1994-10-14 1994-10-14 New dipeptide derivative, process for its preparation and medicinal products containing this compound
DE4436772 1994-10-14
PCT/EP1995/003982 WO1996011941A1 (en) 1994-10-14 1995-10-10 Dipeptide derivatives, process for producing them and medicaments containing these compounds

Publications (1)

Publication Number Publication Date
AU3804795A true AU3804795A (en) 1996-05-06

Family

ID=6530791

Family Applications (1)

Application Number Title Priority Date Filing Date
AU38047/95A Abandoned AU3804795A (en) 1994-10-14 1995-10-10 Dipeptide derivatives, process for producing them and medicaments containing these compounds

Country Status (9)

Country Link
EP (1) EP0788510B1 (en)
JP (1) JPH10507191A (en)
AT (1) ATE189229T1 (en)
AU (1) AU3804795A (en)
CA (1) CA2202379A1 (en)
DE (2) DE4436772A1 (en)
IL (1) IL115585A (en)
WO (1) WO1996011941A1 (en)
ZA (1) ZA958644B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6716869B2 (en) 2001-12-17 2004-04-06 Pharmacia Corporation Protease inhibitors of the coagulation cascade isolated from Dysidea sponges
KR101086259B1 (en) 2004-12-22 2011-11-24 에스케이케미칼주식회사 Composition comprising Oscillatoria agardhii extracts for prevention and treatment of cancer and method of preparing the extracts

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3505555A1 (en) * 1985-02-18 1986-09-11 Behringwerke Ag, 3550 Marburg NEW OLIGOPEPTIDYLARGININOL DERIVATIVES AND THEIR HOMOLOGOLOGY, METHOD FOR THE PRODUCTION THEREOF, THE USE THEREOF AND MEANS CONTAINING THEM
SE9103612D0 (en) * 1991-12-04 1991-12-04 Astra Ab NEW PEPTIDE DERIVATIVES

Also Published As

Publication number Publication date
ZA958644B (en) 1997-04-14
WO1996011941A1 (en) 1996-04-25
CA2202379A1 (en) 1996-04-25
ATE189229T1 (en) 2000-02-15
DE59507710D1 (en) 2000-03-02
DE4436772A1 (en) 1996-04-18
IL115585A (en) 1999-09-22
IL115585A0 (en) 1996-01-19
EP0788510A1 (en) 1997-08-13
EP0788510B1 (en) 2000-01-26
JPH10507191A (en) 1998-07-14

Similar Documents

Publication Publication Date Title
MY132115A (en) Novel thrombin inhibitors
AU7650294A (en) Aminocyclohexylesters and uses thereof
TW289757B (en)
IL117782A0 (en) Tricyclic compounds
MY111556A (en) Substituted azadioxacycloalkenes.
AU5485698A (en) Oxyiminopregnancarbolactone
AU4712396A (en) Chiral methylphenyloxazolidinones
MY132820A (en) Novel thrombin inhibitors
CA2019404A1 (en) 11 beta-aryl-4-estrenes, process for their production as well as their use as pharmaceutical agents
AU8974298A (en) 1,4,7,10-tetraazabicyclo{8.2.2}tetradecan-2-one, a process for the preparation thereof and the use thereof for the preparation of tetraazamacrocycles
MX9704893A (en) Lewis x derivative and process for producing the same.
WO1991001958A3 (en) 11β-ARYL-GONA-4,9-DIEN-3-ONES
MX9803672A (en) New phenylamidine derivatives, a process for preparing the same and their use as medicaments.
AU1306795A (en) Anticonvulsant pseudofructopyranose sulfamates
YU12000A (en) Substituted 1,2,3,4,,5,6,-hexahydro-2,6-methano-3- benzazocine-10-oles, method for the production and use thereof as medicaments
AU3804795A (en) Dipeptide derivatives, process for producing them and medicaments containing these compounds
AU8631698A (en) A process for the preparation of tetraazamacrocycles
MX9801133A (en) Didepsipeptide-based endoparasiticides, new didepsipeptides and process for preparing the same.
TW330933B (en) Furanoeremophilane and eremophilanolide sesquiterpenes for treatment of diabetes
AU1444695A (en) N-oxides of 4-arylpiperazines and 4-arylpiperidines as antipsychotic drugs
MX9603087A (en) Process to obtain substituted aminocarbonyltriazolinones.
AU1192097A (en) 3-aminoethyl-n-amidino-2,5-dihydropyrrole derivatives having arginine mimetic properties
AU4714796A (en) Cobaltous oxide containing finely-dispersed metallic cobalt, methods of producing the same and use thereof
AU6221696A (en) Phosphinic acid derivatives with metallopeptidase inhibitory activity
MY113432A (en) Substituted benzenesulfonylureas and -thioureas, processes for their preparation, their use for the production of pharmaceutical preparations, and medicaments containing them