ZA955754B - Urea and thiourea derivatives of azolones - Google Patents
Urea and thiourea derivatives of azolonesInfo
- Publication number
- ZA955754B ZA955754B ZA955754A ZA955754A ZA955754B ZA 955754 B ZA955754 B ZA 955754B ZA 955754 A ZA955754 A ZA 955754A ZA 955754 A ZA955754 A ZA 955754A ZA 955754 B ZA955754 B ZA 955754B
- Authority
- ZA
- South Africa
- Prior art keywords
- azolones
- urea
- thiourea derivatives
- thiourea
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/70—One oxygen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D249/12—Oxygen or sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP94202017 | 1994-07-12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA955754B true ZA955754B (en) | 1997-01-13 |
Family
ID=8217030
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA955754A ZA955754B (en) | 1994-07-12 | 1995-07-11 | Urea and thiourea derivatives of azolones |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US5639754A (xx) |
| JP (1) | JPH10502384A (xx) |
| KR (1) | KR970704738A (xx) |
| CN (1) | CN1071330C (xx) |
| AU (1) | AU684987B2 (xx) |
| BR (1) | BR9508378A (xx) |
| CA (1) | CA2194565A1 (xx) |
| CZ (1) | CZ2597A3 (xx) |
| FI (1) | FI970111A (xx) |
| HU (1) | HUT76647A (xx) |
| IL (1) | IL114535A (xx) |
| MX (1) | MX9700339A (xx) |
| NO (1) | NO970087L (xx) |
| NZ (1) | NZ290117A (xx) |
| PL (1) | PL318141A1 (xx) |
| SK (1) | SK4597A3 (xx) |
| WO (1) | WO1996001820A1 (xx) |
| ZA (1) | ZA955754B (xx) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5639754A (en) * | 1994-07-12 | 1997-06-17 | Janssen Pharmaceutica N.V. | Urea and thiourea derivatives of azolones |
| US6312723B1 (en) | 1999-08-26 | 2001-11-06 | Robert R. Whittle | Pharmaceutical unit dosage form |
| US6326384B1 (en) | 1999-08-26 | 2001-12-04 | Robert R. Whittle | Dry blend pharmaceutical unit dosage form |
| US6312712B1 (en) | 1999-08-26 | 2001-11-06 | Robert R. Whittle | Method of improving bioavailability |
| US6316020B1 (en) | 1999-08-26 | 2001-11-13 | Robert R. Whittle | Pharmaceutical formulations |
| US6268385B1 (en) | 1999-08-26 | 2001-07-31 | Robert R. Whittle | Dry blend pharmaceutical formulations |
| US6262086B1 (en) | 1999-08-26 | 2001-07-17 | Robert R. Whittle | Pharmaceutical unit dosage form |
| US6369087B1 (en) | 1999-08-26 | 2002-04-09 | Robert R. Whittle | Alkoxy substituted benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same |
| US6262085B1 (en) | 1999-08-26 | 2001-07-17 | Robert R. Whittle | Alkoxy substituted Benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same |
| US6780880B1 (en) * | 1999-08-26 | 2004-08-24 | Robert R. Whittle | FT-Raman spectroscopic measurement |
| JP2004501867A (ja) * | 2000-03-07 | 2004-01-22 | ランバクシー ラボラトリーズ リミテッド | 真菌感染症に対する治療薬としてのアゾール化合物 |
| NZ523526A (en) | 2000-07-20 | 2004-10-29 | Neurogen Corp | Diaryl piperazines as capsaicin receptor ligands |
| ATE452637T1 (de) | 2001-01-29 | 2010-01-15 | Shionogi & Co | Arzneipräparat, das als wirkstoff 5-methyl-1- phenyl-2-(1h)-pyridon enthält |
| WO2004083235A2 (en) * | 2003-03-19 | 2004-09-30 | Exelixis Inc. | Tie-2 modulators and methods of use |
| TWI372066B (en) * | 2003-10-01 | 2012-09-11 | Wyeth Corp | Pantoprazole multiparticulate formulations |
| JPWO2007020888A1 (ja) | 2005-08-12 | 2009-02-26 | 武田薬品工業株式会社 | 脳・神経細胞保護剤および睡眠障害治療薬 |
| US8633197B2 (en) | 2007-06-08 | 2014-01-21 | Janssen Pharmaceutica N.V. | Piperidine/piperazine derivatives |
| CA2687754C (en) | 2007-06-08 | 2015-12-08 | Janssen Pharmaceutica N.V. | Piperidine, piperazine derivatives for use as dgat inhibitors |
| JO2972B1 (en) | 2007-06-08 | 2016-03-15 | جانسين فارماسوتيكا ان. في | Piperidine / piperazine derivatives |
| CA2687912C (en) | 2007-06-08 | 2015-11-03 | Janssen Pharmaceutica N.V. | Piperidine/piperazine derivatives |
| WO2009082437A2 (en) | 2007-12-21 | 2009-07-02 | Ligand Pharmaceuticals Incorporated | Selective androgen receptor modulators (sarms) and uses thereof |
| UY31863A (es) | 2008-06-05 | 2010-01-05 | Janssen Pharmaceutica Nv | Combinaciones de drogas que comprenden un inhibidor de dgat y un agonista de ppar |
| EP2709609B1 (en) | 2011-05-17 | 2017-10-04 | Shionogi & Co., Ltd. | Heterocyclic compounds |
| KR20160147007A (ko) | 2014-05-30 | 2016-12-21 | 화이자 인코포레이티드 | 선택적인 안드로겐 수용체 조절제로서의 카보니트릴 유도체 |
| CA2937365C (en) | 2016-03-29 | 2018-09-18 | F. Hoffmann-La Roche Ag | Granulate formulation of 5-methyl-1-phenyl-2-(1h)-pyridone and method of making the same |
| WO2023275715A1 (en) | 2021-06-30 | 2023-01-05 | Pfizer Inc. | Metabolites of selective androgen receptor modulators |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4791111A (en) * | 1985-12-23 | 1988-12-13 | Janssen Pharmaceutica, N.V. | [[4-[4-(4-phenyl-1-piperazinyl)phenoxymethyl]-1,3-dioxolan-2-yl]methyl]-1H-imidazoles and 1H-1,2,4-triazoles having anti-microbial properties |
| CA1331757C (en) * | 1988-02-29 | 1994-08-30 | Janssen Pharmaceutica Naamloze Vennootschap | 5-lipoxygenase inhibiting 4-(4-phenyl-1-piperazinyl)phenols |
| TW218017B (xx) * | 1992-04-28 | 1993-12-21 | Takeda Pharm Industry Co Ltd | |
| TW279864B (xx) * | 1993-02-19 | 1996-07-01 | Janssen Pharmaceutica Nv | |
| US5639754A (en) * | 1994-07-12 | 1997-06-17 | Janssen Pharmaceutica N.V. | Urea and thiourea derivatives of azolones |
| US5571811A (en) * | 1994-07-12 | 1996-11-05 | Janssen Pharmaceutica N.V. | Sulfonamide derivatives of azolones |
-
1995
- 1995-05-23 US US08/448,155 patent/US5639754A/en not_active Expired - Fee Related
- 1995-07-05 BR BR9508378A patent/BR9508378A/pt not_active Application Discontinuation
- 1995-07-05 JP JP8504110A patent/JPH10502384A/ja active Pending
- 1995-07-05 MX MX9700339A patent/MX9700339A/es unknown
- 1995-07-05 CZ CZ9725A patent/CZ2597A3/cs unknown
- 1995-07-05 AU AU30756/95A patent/AU684987B2/en not_active Ceased
- 1995-07-05 HU HU9700078A patent/HUT76647A/hu unknown
- 1995-07-05 WO PCT/EP1995/002617 patent/WO1996001820A1/en not_active Application Discontinuation
- 1995-07-05 KR KR1019970700088A patent/KR970704738A/ko not_active Application Discontinuation
- 1995-07-05 PL PL95318141A patent/PL318141A1/xx unknown
- 1995-07-05 CA CA002194565A patent/CA2194565A1/en not_active Abandoned
- 1995-07-05 NZ NZ290117A patent/NZ290117A/en unknown
- 1995-07-05 CN CN95194024A patent/CN1071330C/zh not_active Expired - Fee Related
- 1995-07-05 SK SK45-97A patent/SK4597A3/sk unknown
- 1995-07-05 US US08/776,622 patent/US5811426A/en not_active Expired - Fee Related
- 1995-07-11 ZA ZA955754A patent/ZA955754B/xx unknown
- 1995-07-11 IL IL11453595A patent/IL114535A/xx active IP Right Grant
-
1997
- 1997-01-09 NO NO970087A patent/NO970087L/no not_active Application Discontinuation
- 1997-01-10 FI FI970111A patent/FI970111A/fi unknown
Also Published As
| Publication number | Publication date |
|---|---|
| MX9700339A (es) | 1997-05-31 |
| CN1152309A (zh) | 1997-06-18 |
| KR970704738A (ko) | 1997-09-06 |
| SK4597A3 (en) | 1997-11-05 |
| CZ2597A3 (en) | 1997-10-15 |
| AU3075695A (en) | 1996-02-09 |
| FI970111A0 (fi) | 1997-01-10 |
| HUT76647A (en) | 1997-10-28 |
| NZ290117A (en) | 1997-11-24 |
| US5811426A (en) | 1998-09-22 |
| US5639754A (en) | 1997-06-17 |
| AU684987B2 (en) | 1998-01-08 |
| NO970087D0 (no) | 1997-01-09 |
| PL318141A1 (en) | 1997-05-12 |
| IL114535A0 (en) | 1995-11-27 |
| IL114535A (en) | 1999-04-11 |
| CA2194565A1 (en) | 1996-01-25 |
| JPH10502384A (ja) | 1998-03-03 |
| CN1071330C (zh) | 2001-09-19 |
| NO970087L (no) | 1997-03-10 |
| WO1996001820A1 (en) | 1996-01-25 |
| BR9508378A (pt) | 1997-10-28 |
| FI970111A (fi) | 1997-01-10 |
| HU9700078D0 (en) | 1997-02-28 |
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