ZA945146B - Novel synthesis - Google Patents

Novel synthesis

Info

Publication number
ZA945146B
ZA945146B ZA945146A ZA945146A ZA945146B ZA 945146 B ZA945146 B ZA 945146B ZA 945146 A ZA945146 A ZA 945146A ZA 945146 A ZA945146 A ZA 945146A ZA 945146 B ZA945146 B ZA 945146B
Authority
ZA
South Africa
Prior art keywords
novel synthesis
synthesis
novel
Prior art date
Application number
ZA945146A
Other languages
English (en)
Inventor
Joseph R Flisak
Stephen Torey Ross
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of ZA945146B publication Critical patent/ZA945146B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/82Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C239/00Compounds containing nitrogen-to-halogen bonds; Hydroxylamino compounds or ethers or esters thereof
    • C07C239/08Hydroxylamino compounds or their ethers or esters
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/58Radicals substituted by nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA945146A 1993-07-14 1994-07-14 Novel synthesis ZA945146B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US9149493A 1993-07-14 1993-07-14

Publications (1)

Publication Number Publication Date
ZA945146B true ZA945146B (en) 1995-02-24

Family

ID=22228076

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA945146A ZA945146B (en) 1993-07-14 1994-07-14 Novel synthesis

Country Status (6)

Country Link
US (1) US5663368A (fr)
EP (1) EP0708753A4 (fr)
JP (1) JPH09500139A (fr)
AU (1) AU7366794A (fr)
WO (1) WO1995002574A1 (fr)
ZA (1) ZA945146B (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0935669B1 (fr) * 1996-05-20 2002-07-31 Fraunhofer-Gesellschaft Zur Förderung Der Angewandten Forschung E.V. Synthese enzymatique d'acides hydroxamiques optiquement actifs et leur conversion en amines primaires optiquement actives par transposition de lossen
US6080874A (en) * 1997-09-25 2000-06-27 Abbott Laboratories Synthesis and isolation of N-(aryl or heteroaryl)-alkyl-N-hydroxyurea
TW514634B (en) * 1997-10-14 2002-12-21 Lilly Co Eli Process to make chiral compounds
US6008412A (en) * 1997-10-14 1999-12-28 Eli Lilly And Company Process to make chiral compounds
US7435837B2 (en) * 2003-10-24 2008-10-14 Wyeth Dihydrobenzofuranyl alkanamine derivatives and methods for using same
US20050261347A1 (en) * 2003-10-24 2005-11-24 Wyeth Dihydrobenzofuranyl alkanamine derivatives and methods for using same
US8003684B2 (en) * 2006-02-21 2011-08-23 Cornerstone Therapeutics, Inc. Crystal form and pharmaceutical compositions of (+)-R-zileuton
WO2013028880A1 (fr) 2011-08-23 2013-02-28 Cornerstone Therapeutics Inc. Utilisation de zileuton dans le traitement des polypes nasaux chez des patients atteints de mucoviscidose
WO2019191624A1 (fr) 2018-03-29 2019-10-03 Arbutus Biopharma, Inc. Composés 1,1'-biphényle substitués, analogues de ceux-ci, et procédés les utilisant

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1390260A (en) * 1918-12-18 1921-09-06 Sulzberger Nathan Salts of aromatic hydroxyl amins
US2132454A (en) * 1935-07-06 1938-10-11 Us Rubber Prod Inc Manufacture of hydroxy amino compounds
US3118933A (en) * 1959-12-28 1964-01-21 Hoffmann La Roche N-(alpha-methyl-2, 4-dichlorophenethyl) hydroxylamine and its salts
US3163677A (en) * 1961-08-07 1964-12-29 American Cyanamid Co Process for preparing n, n, o-trisubstituted hydroxyl amines and n, n-disubstituted nitroxides and products
US4983771A (en) * 1989-09-18 1991-01-08 Hexcel Corporation Method for resolution of D,L-alpha-phenethylamine with D(-)mandelic acid
US5264577A (en) * 1992-04-22 1993-11-23 Warner-Lambert Company Cyclic amino acids and derivatives thereof

Also Published As

Publication number Publication date
AU7366794A (en) 1995-02-13
US5663368A (en) 1997-09-02
WO1995002574A1 (fr) 1995-01-26
EP0708753A1 (fr) 1996-05-01
EP0708753A4 (fr) 1996-10-02
JPH09500139A (ja) 1997-01-07

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