ZA938799B - Novel heterocyclic compounds with anti-asthmatic/anti-allergic, anti-inflammatory, positive inotropic and blood pressure-reducing effect. - Google Patents

Novel heterocyclic compounds with anti-asthmatic/anti-allergic, anti-inflammatory, positive inotropic and blood pressure-reducing effect.

Info

Publication number
ZA938799B
ZA938799B ZA938799A ZA938799A ZA938799B ZA 938799 B ZA938799 B ZA 938799B ZA 938799 A ZA938799 A ZA 938799A ZA 938799 A ZA938799 A ZA 938799A ZA 938799 B ZA938799 B ZA 938799B
Authority
ZA
South Africa
Prior art keywords
asthmatic
allergic
inflammatory
blood pressure
heterocyclic compounds
Prior art date
Application number
ZA938799A
Inventor
Bernhard Kutscher
Juergen Engel
Peter Metzenauer
Ute Achterrath-Tuckermann
Stefan Szelenyi
Original Assignee
Asta Medica Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asta Medica Ag filed Critical Asta Medica Ag
Publication of ZA938799B publication Critical patent/ZA938799B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ZA938799A 1992-11-25 1993-11-24 Novel heterocyclic compounds with anti-asthmatic/anti-allergic, anti-inflammatory, positive inotropic and blood pressure-reducing effect. ZA938799B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4239540A DE4239540A1 (en) 1992-11-25 1992-11-25 New heterocyclic compounds with anti-asthmatic / anti-allergic, anti-inflammatory, positive inotropic and hypotensive effects

Publications (1)

Publication Number Publication Date
ZA938799B true ZA938799B (en) 1994-06-30

Family

ID=6473572

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA938799A ZA938799B (en) 1992-11-25 1993-11-24 Novel heterocyclic compounds with anti-asthmatic/anti-allergic, anti-inflammatory, positive inotropic and blood pressure-reducing effect.

Country Status (18)

Country Link
EP (1) EP0599152A1 (en)
JP (1) JPH06239868A (en)
KR (1) KR940011464A (en)
CN (1) CN1094050A (en)
AU (1) AU5190193A (en)
BR (1) BR9304818A (en)
CA (1) CA2109900A1 (en)
CZ (1) CZ252493A3 (en)
DE (1) DE4239540A1 (en)
FI (1) FI935218A (en)
HU (1) HUT70491A (en)
IL (1) IL107739A0 (en)
MX (1) MX9307307A (en)
NO (1) NO934249L (en)
PL (1) PL301188A1 (en)
SI (1) SI9300609A (en)
SK (1) SK131193A3 (en)
ZA (1) ZA938799B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002067675A2 (en) 2000-10-27 2002-09-06 Dow Agrosciences Llc Substituted 4,5-dihydro-1,2,4-triazin-6-ones, 1,2,4-triazin-6-ones, and their use as fungicides and insecticides

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2301574T3 (en) 2000-10-27 2008-07-01 Dow Agrosciences Llc 4,5-DIHIDRO-1,2,4-TRIAZIN-3-ONAS, 1,2,4-TRIAZIN-3-SUBSTITUTED WAVES AND ITS USE AS FUNGICIDES AND INSECTICIDES.
JP5529004B2 (en) * 2007-03-27 2014-06-25 シンタ ファーマシューティカルズ コーポレーション Triazinone and diazinone derivatives useful as HSP90 inhibitors
WO2020157189A1 (en) 2019-02-01 2020-08-06 Bayer Aktiengesellschaft 1,2,4-triazin-6(1h)-one compounds for the treatment of hyperproliferative diseases

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3919216A (en) * 1974-11-04 1975-11-11 Dow Chemical Co 6-(Alkyl)-3,4,6,7-tetrahydro-1,2,4-triazinoquinazolines
US3946010A (en) * 1975-04-09 1976-03-23 E. R. Squibb & Sons, Inc. 3-Phenyl-2,5-dihydro-as-triazin-6 (1H)-ones
DE3172252D1 (en) * 1980-11-14 1985-10-17 Ici Plc Heterocyclic compounds
DD160343A1 (en) * 1981-06-25 1983-06-01 Karl Kottke PROCESS FOR PREPARING 2,5-DISUBSTITUTED 1H-1,6-DIOXO-5,6-DIHYDRO-AS-TRIAZINO (4,3-A) CHINAZOLINES
DE3126837A1 (en) * 1981-07-08 1983-01-27 Hoechst Ag, 6000 Frankfurt TRIAZINO- (2,1-A) ISOCHINOLINE DERIVATIVES
US4495185A (en) * 1981-11-12 1985-01-22 Imperial Chemical Industries, Plc 1,2,4-Triazin-3(2H) ones
US4362550A (en) * 1981-12-21 1982-12-07 Eli Lilly And Company Herbicidal triazinones
US4581356A (en) * 1983-03-22 1986-04-08 Fujisawa Pharmaceutical Co., Ltd. Triazine derivatives, and pharmaceutical compositions comprising the same
GB8310435D0 (en) * 1983-04-18 1983-05-25 Fujisawa Pharmaceutical Co Triazine derivatives
JPS59196874A (en) * 1983-04-22 1984-11-08 Fujisawa Pharmaceut Co Ltd Triazine derivative, its preparation, and drug composition containing it
FR2567518B1 (en) * 1984-07-11 1987-11-13 Sanofi Sa NOVEL NITROGEN HETEROCYCLIC CORE COMPOUNDS, THEIR PREPARATION AND THE MEDICINAL PRODUCTS CONTAINING THE SAME
US4898862A (en) * 1986-03-20 1990-02-06 Sankyo Company Limited 1,2,4-triazinone derivatives, their preparation and use
GB8903130D0 (en) * 1989-02-11 1989-03-30 Orion Yhtymae Oy Substituted pyridazinones
DE3913597A1 (en) * 1989-04-25 1990-11-08 Heumann Pharma Gmbh & Co DIAZINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS
FR2671551B1 (en) * 1991-01-15 1993-03-12 Adir NOVEL ARYL TRIAZINIC STRUCTURE COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME.

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002067675A2 (en) 2000-10-27 2002-09-06 Dow Agrosciences Llc Substituted 4,5-dihydro-1,2,4-triazin-6-ones, 1,2,4-triazin-6-ones, and their use as fungicides and insecticides

Also Published As

Publication number Publication date
IL107739A0 (en) 1994-02-27
DE4239540A1 (en) 1994-05-26
BR9304818A (en) 1994-06-21
EP0599152A1 (en) 1994-06-01
HUT70491A (en) 1995-10-30
PL301188A1 (en) 1994-07-11
NO934249L (en) 1994-05-26
NO934249D0 (en) 1993-11-24
CN1094050A (en) 1994-10-26
FI935218A (en) 1994-05-26
SK131193A3 (en) 1994-12-07
MX9307307A (en) 1994-06-30
FI935218A0 (en) 1993-11-24
KR940011464A (en) 1994-06-21
AU5190193A (en) 1994-06-09
CA2109900A1 (en) 1994-05-26
JPH06239868A (en) 1994-08-30
CZ252493A3 (en) 1994-06-15
SI9300609A (en) 1994-06-30

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