ZA936872B - 3,3'-disubstituted-1,3-dihydro-2H-pyrrolo[2,3-B]heterocyclic-2-one useful in the treatment of cognitive disorders of man - Google Patents
3,3'-disubstituted-1,3-dihydro-2H-pyrrolo[2,3-B]heterocyclic-2-one useful in the treatment of cognitive disorders of manInfo
- Publication number
- ZA936872B ZA936872B ZA936872A ZA936872A ZA936872B ZA 936872 B ZA936872 B ZA 936872B ZA 936872 A ZA936872 A ZA 936872A ZA 936872 A ZA936872 A ZA 936872A ZA 936872 B ZA936872 B ZA 936872B
- Authority
- ZA
- South Africa
- Prior art keywords
- pyrrolo
- disubstituted
- dihydro
- heterocyclic
- man
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/947,152 US5278162A (en) | 1992-09-18 | 1992-09-18 | 3,3'-disubstituted-1,3-dihydro-2H-pyrrolo[2,3-b]heterocyclic-2-one useful in the treatment of cognitive disorders of man |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA936872B true ZA936872B (en) | 1995-03-17 |
Family
ID=25485622
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA936872A ZA936872B (en) | 1992-09-18 | 1993-09-17 | 3,3'-disubstituted-1,3-dihydro-2H-pyrrolo[2,3-B]heterocyclic-2-one useful in the treatment of cognitive disorders of man |
Country Status (10)
Country | Link |
---|---|
US (1) | US5278162A (de) |
EP (1) | EP0660833A1 (de) |
JP (1) | JPH08501550A (de) |
CN (1) | CN1094406A (de) |
AU (1) | AU4856893A (de) |
CA (1) | CA2144636A1 (de) |
IL (1) | IL107003A0 (de) |
TW (1) | TW248560B (de) |
WO (1) | WO1994006793A1 (de) |
ZA (1) | ZA936872B (de) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5296478A (en) * | 1992-10-07 | 1994-03-22 | The Dupont Merck Pharmaceutical Co. | 1-substituted oxindoles as cognition enhancers |
US5854232A (en) * | 1994-04-29 | 1998-12-29 | Pfizer Inc. | Acyclic anc cyclic amides as neurotransmitter release enhancers |
US5744476A (en) * | 1994-06-27 | 1998-04-28 | Interneuron Pharmaceuticals, Inc. | Dopamine D1 agonists for the treatment of dementia |
MY144968A (en) * | 2005-04-11 | 2011-11-30 | Xenon Pharmaceuticals Inc | Spiro-oxindole compounds and their uses as therapeutic agents |
MY145694A (en) | 2005-04-11 | 2012-03-30 | Xenon Pharmaceuticals Inc | Spiroheterocyclic compounds and their uses as therapeutic agents |
AR053713A1 (es) * | 2005-04-20 | 2007-05-16 | Xenon Pharmaceuticals Inc | Compuestos heterociclicos y sus usos como agentes terapeuticos |
US20110294842A9 (en) * | 2006-10-12 | 2011-12-01 | Xenon Pharmaceuticals Inc. | Spiro (furo [3, 2-c] pyridine-3-3' -indol) -2' (1'h)-one derivatives and related compounds for the treatment of sodium-channel mediated diseases, such as pain |
JP5460324B2 (ja) * | 2006-10-12 | 2014-04-02 | ゼノン・ファーマシューティカルズ・インコーポレイテッド | 治療剤としてのスピロ−オキシインドール化合物の使用 |
BRPI0719166A2 (pt) * | 2006-10-12 | 2014-06-03 | Xenon Pharmaceuticals Inc | Derivados de espiro-oxindol tricíclicos e seus usos como agentes terapêuticos |
DK2350090T3 (en) * | 2008-10-17 | 2015-09-07 | Xenon Pharmaceuticals Inc | Spiro-oxindole compounds and their use as therapeutic agents |
EP2350091B1 (de) * | 2008-10-17 | 2015-06-03 | Xenon Pharmaceuticals Inc. | Spiro-oxindol verbindungen und ihre verwendung als therapeutische wirkstoffe |
AR077252A1 (es) | 2009-06-29 | 2011-08-10 | Xenon Pharmaceuticals Inc | Enantiomeros de compuestos de espirooxindol y sus usos como agentes terapeuticos |
WO2011047174A1 (en) | 2009-10-14 | 2011-04-21 | Xenon Pharmaceuticals Inc. | Synthetic methods for spiro-oxindole compounds |
WO2011047173A2 (en) * | 2009-10-14 | 2011-04-21 | Xenon Pharmaceuticals Inc. | Pharmaceutical compositions for oral administration |
US9504671B2 (en) | 2010-02-26 | 2016-11-29 | Xenon Pharmaceuticals Inc. | Pharmaceutical compositions of spiro-oxindole compound for topical administration and their use as therapeutic agents |
US9682033B2 (en) | 2015-02-05 | 2017-06-20 | Teva Pharmaceuticals International Gmbh | Methods of treating postherpetic neuralgia with a topical formulation of a spiro-oxindole compound |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4760083A (en) * | 1986-04-10 | 1988-07-26 | E. I. Dupont De Nemours & Company | 3,3-disubstituted indolines |
GB8714371D0 (en) * | 1987-06-19 | 1987-07-22 | Smith Kline French Lab | Process |
EP0419561A1 (de) * | 1988-06-14 | 1991-04-03 | Schering Corporation | Heterobicyclische verbindungen mit antientzündungsaktivität |
US5006537A (en) * | 1989-08-02 | 1991-04-09 | Hoechst-Roussel Pharmaceuticals, Inc. | 1,3-dihydro-1-(pyridinylamino)-2H-indol-2-ones |
-
1992
- 1992-09-18 US US07/947,152 patent/US5278162A/en not_active Expired - Fee Related
-
1993
- 1993-09-14 IL IL107003A patent/IL107003A0/xx unknown
- 1993-09-16 AU AU48568/93A patent/AU4856893A/en not_active Abandoned
- 1993-09-16 WO PCT/US1993/008563 patent/WO1994006793A1/en not_active Application Discontinuation
- 1993-09-16 CA CA002144636A patent/CA2144636A1/en not_active Abandoned
- 1993-09-16 EP EP93921493A patent/EP0660833A1/de active Pending
- 1993-09-16 JP JP6508194A patent/JPH08501550A/ja active Pending
- 1993-09-17 ZA ZA936872A patent/ZA936872B/xx unknown
- 1993-09-18 CN CN93119623A patent/CN1094406A/zh active Pending
- 1993-09-27 TW TW082107957A patent/TW248560B/zh active
Also Published As
Publication number | Publication date |
---|---|
JPH08501550A (ja) | 1996-02-20 |
EP0660833A1 (de) | 1995-07-05 |
AU4856893A (en) | 1994-04-12 |
TW248560B (de) | 1995-06-01 |
CA2144636A1 (en) | 1994-03-31 |
US5278162A (en) | 1994-01-11 |
IL107003A0 (en) | 1993-12-28 |
CN1094406A (zh) | 1994-11-02 |
WO1994006793A1 (en) | 1994-03-31 |
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