ZA936434B - Phosphono substituted tetrazole derivatives - Google Patents

Phosphono substituted tetrazole derivatives

Info

Publication number
ZA936434B
ZA936434B ZA936434A ZA936434A ZA936434B ZA 936434 B ZA936434 B ZA 936434B ZA 936434 A ZA936434 A ZA 936434A ZA 936434 A ZA936434 A ZA 936434A ZA 936434 B ZA936434 B ZA 936434B
Authority
ZA
South Africa
Prior art keywords
tetrazole derivatives
substituted tetrazole
phosphono substituted
phosphono
derivatives
Prior art date
Application number
ZA936434A
Other languages
English (en)
Inventor
Stephane De Lombaert
Original Assignee
Ciba Geigy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy filed Critical Ciba Geigy
Publication of ZA936434B publication Critical patent/ZA936434B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6524—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having four or more nitrogen atoms as the only ring hetero atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA936434A 1992-09-03 1993-09-01 Phosphono substituted tetrazole derivatives ZA936434B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/940,118 US5273990A (en) 1992-09-03 1992-09-03 Phosphono substituted tetrazole derivatives

Publications (1)

Publication Number Publication Date
ZA936434B true ZA936434B (en) 1994-03-09

Family

ID=25474265

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA936434A ZA936434B (en) 1992-09-03 1993-09-01 Phosphono substituted tetrazole derivatives

Country Status (3)

Country Link
US (1) US5273990A (esLanguage)
TW (1) TW246675B (esLanguage)
ZA (1) ZA936434B (esLanguage)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HRP950558A2 (en) * 1994-11-15 1997-12-31 Scott M. Wilhelm Substituted 4-biarylbutric or biarylpentanoic acids and derivatives as matrix metalloprotease inhibitors
US5583123A (en) * 1994-12-22 1996-12-10 Ciba-Geigy Corporation Certain tetrazole derivatives
US5550119A (en) * 1995-03-02 1996-08-27 Ciba-Geigy Corporation Phosphono substituted tetrazole derivatives as ECE inhibitors
WO1996033170A1 (en) * 1995-04-21 1996-10-24 Novarits Ag N-aroylamino acid amides as endothelin inhibitors
US7468390B2 (en) 2002-01-17 2008-12-23 Novartis Ag Methods of treatment and pharmaceutical composition
AU2003265398A1 (en) * 2002-08-09 2004-02-25 Transtech Pharma, Inc. Aryl and heteroaryl compounds and methods to modulate coagulation
US7208601B2 (en) * 2003-08-08 2007-04-24 Mjalli Adnan M M Aryl and heteroaryl compounds, compositions, and methods of use
US7501538B2 (en) * 2003-08-08 2009-03-10 Transtech Pharma, Inc. Aryl and heteroaryl compounds, compositions and methods of use
AR057882A1 (es) 2005-11-09 2007-12-26 Novartis Ag Compuestos de accion doble de bloqueadores del receptor de angiotensina e inhibidores de endopeptidasa neutra
MY151993A (en) 2007-01-12 2014-07-31 Novartis Ag Process for preparing 5-biphenyl-4-amino-2-methyl pentanoic acid
AU2008350907A1 (en) 2007-12-11 2009-08-27 Viamet Pharmaceuticals, Inc. Metalloenzyme inhibitors using metal binding moieties in combination with targeting moieties
UY32660A (es) 2009-05-28 2010-12-31 Novartis Ag Derivados aminobutricos sustituidos como inhibidores de neprilisina
ME01923B (me) 2009-05-28 2015-05-20 Novartis Ag Supstituisani derivati aminopropionske kiseline kao inhibitori neprilizina
JO2967B1 (en) * 2009-11-20 2016-03-15 نوفارتس ايه جي Acetic acid derivatives of carbamoyl methyl amino are substituted as new NEP inhibitors
KR101476937B1 (ko) 2010-08-23 2014-12-24 노파르티스 아게 Ｎｅｐ 억제제의 제조를 위한 중간체의 제조 방법
DK2887961T3 (da) 2012-08-24 2021-07-19 Novartis Ag Nep-inhibitorer til behandling af sygdomme, der er kendetegnet ved atrieforstørrelse eller -remodellering
CA2900226A1 (en) 2013-02-14 2014-08-21 Novartis Ag Substituted bisphenyl butanoic acid derivatives as nep inhibitors with improved in vivo efficacy
LT2956464T (lt) 2013-02-14 2018-07-10 Novartis Ag Pakeisti bisfenilbutanoinės fosfonrūgšties dariniai, kaip nep (neutralios endopeptidazės) inhibitoriai
WO2017033128A1 (en) 2015-08-25 2017-03-02 Novartis Ag Biphenyl-substitued 4-amino-butyric acid derivatives and their use in the synthesis of nep inhibitors
WO2017072636A1 (en) 2015-10-29 2017-05-04 Cadila Healthcare Limited Pharmaceutical synergistic combination
UY38072A (es) 2018-02-07 2019-10-01 Novartis Ag Compuestos derivados de éster butanoico sustituido con bisfenilo como inhibidores de nep, composiciones y combinaciones de los mismos

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CY1406A (en) * 1980-12-18 1988-04-22 Schering Corp Substituted dipeptides, processes for their preparation and pharmaceutical compositions containing them and their use in the inhibition of enkephalinase
US4939261A (en) * 1984-06-08 1990-07-03 Ciba-Geigy Corporation N-substituted butyramide derivatives useful for treatment of conditions responsive to inhibition of enkephalinase
EP0225292A3 (en) * 1985-12-06 1988-11-30 Ciba-Geigy Ag Certain n-substituted butyramide derivatives
US5155100A (en) * 1991-05-01 1992-10-13 Ciba-Geigy Corporation Phosphono/biaryl substituted dipeptide derivatives

Also Published As

Publication number Publication date
TW246675B (esLanguage) 1995-05-01
US5273990A (en) 1993-12-28

Similar Documents

Publication Publication Date Title
HU9201430D0 (en) Phosphono/biaril-dipeptide derivatives
ZA936434B (en) Phosphono substituted tetrazole derivatives
PL307812A1 (en) Substituted thiazolydinone derivatives
EP0592367A3 (en) Phosphono/biaryl substituted dipeptide derivatives
HU9501944D0 (en) Phosphonic acid derivatives
GB9211706D0 (en) Peptidyl derivatives
GB9211707D0 (en) Peptidyl derivatives
IL110144A0 (en) Tetrazole derivatives
GB9305306D0 (en) Pyrrolo-pyridazione derivatives
HU9301955D0 (en) Benzophenone-hydrazone derivatives
HU9301554D0 (en) 1-(3-halogen-4-trifluoro-methyl-phenyl)-tetrazolinone derivatives
ZA931876B (en) 2-Oxoquinoline derivatives
ZA93533B (en) Phosphonic acid derivatives
ZA93144B (en) Substituted benzimidazole derivatives
HU9301112D0 (en) Propenoyl-imidazole derivatives
GB9320940D0 (en) Substituted n-carboxyalkylpeptidyl derivatives as antidegenerative agents
GB9226735D0 (en) Azole derivatives
GB9318255D0 (en) Chlordifluoromethoxyphenyl derivatives
GB9319338D0 (en) Thioalkylthio carbacephalosporin derivatives
HU9300556D0 (en) Substituted phenyl-quinazoline derivatives
FI950925A7 (fi) Fosfono-substituoidut tetratsolijohdannaiset
EP0565961A3 (en) Ethyl-triazolyl derivatives
AU4342796A (en) Certain tetrazole derivatives
HU9301696D0 (en) Pyrimidofuroxane derivatives
GB9223244D0 (en) Phenylpyrazine derivatives