ZA934389B - Peptide compounds having bradykinin-antagonist activity, process for their preparation and the pharmaceutical compositions which contain them - Google Patents

Peptide compounds having bradykinin-antagonist activity, process for their preparation and the pharmaceutical compositions which contain them

Info

Publication number
ZA934389B
ZA934389B ZA934389A ZA934389A ZA934389B ZA 934389 B ZA934389 B ZA 934389B ZA 934389 A ZA934389 A ZA 934389A ZA 934389 A ZA934389 A ZA 934389A ZA 934389 B ZA934389 B ZA 934389B
Authority
ZA
South Africa
Prior art keywords
bradykinin
contain
preparation
pharmaceutical compositions
antagonist activity
Prior art date
Application number
ZA934389A
Inventor
Jean-Luc Fauchere
Christophe Thurieau
Joseph Paladino
Nathalie Kucharczyk
Emmanuel Canet
Original Assignee
Adir
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adir filed Critical Adir
Publication of ZA934389B publication Critical patent/ZA934389B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/18Kallidins; Bradykinins; Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Abstract

Compounds of formula (I): <IMAGE> in which X, X', A1, A2, A3, A4, A5, A6, A7, A8, A 9 and Y are as defined in the description. Medications.
ZA934389A 1992-06-18 1993-06-18 Peptide compounds having bradykinin-antagonist activity, process for their preparation and the pharmaceutical compositions which contain them ZA934389B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9207378A FR2692581B1 (en) 1992-06-18 1992-06-18 New peptide derivatives with bradykinin antagonist activity, their preparation process and the pharmaceutical compositions containing them.

Publications (1)

Publication Number Publication Date
ZA934389B true ZA934389B (en) 1994-01-17

Family

ID=9430857

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA934389A ZA934389B (en) 1992-06-18 1993-06-18 Peptide compounds having bradykinin-antagonist activity, process for their preparation and the pharmaceutical compositions which contain them

Country Status (12)

Country Link
EP (1) EP0578521B1 (en)
JP (1) JP2589937B2 (en)
AT (1) ATE141615T1 (en)
AU (1) AU660809B2 (en)
CA (1) CA2098655A1 (en)
DE (1) DE69304155T2 (en)
DK (1) DK0578521T3 (en)
ES (1) ES2091570T3 (en)
FR (1) FR2692581B1 (en)
GR (1) GR3021472T3 (en)
NZ (1) NZ247914A (en)
ZA (1) ZA934389B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU705883B2 (en) * 1994-10-27 1999-06-03 Fujisawa Pharmaceutical Co., Ltd. Pyridopyrimidones, quinolines and fused N-heretocycles as bradykinin antagonists
FR2739553B1 (en) 1995-10-06 1998-01-02 Oreal USE OF BRADYKININE ANTAGONISTS TO STIMULATE OR INDUCE HAIR GROWTH AND / OR STOP THE HAIR LOSS
DE19612067A1 (en) * 1996-03-27 1997-10-02 Hoechst Ag Use of bradykinin antagonists for the manufacture of medicaments for the treatment of chronic fibrogenetic liver diseases and acute liver diseases
DE19642289A1 (en) 1996-10-14 1998-04-16 Hoechst Ag Use of bradykinin antagonists for the manufacture of medicaments for the treatment and prevention of Alzheimer's disease
US7105172B1 (en) 1999-11-18 2006-09-12 Bolla John D Treatment of rosacea
WO2016151753A1 (en) * 2015-03-24 2016-09-29 日立金属株式会社 Composite cable, composite harness and vehicle

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE63490B1 (en) * 1988-11-24 1995-05-03 Hoechst Ag Peptides having bradykinin antagonist action
MX9100717A (en) * 1990-08-24 1992-04-01 Syntex Inc BRADIQUININE ANTAGONISTS
FR2686343B1 (en) * 1992-01-17 1994-03-11 Adir Cie NOVEL PSEUDOPEPTIDE DERIVATIVES WITH ANTAGONIST ACTIVITY OF BRADYKININE, PROCESS FOR THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.

Also Published As

Publication number Publication date
JP2589937B2 (en) 1997-03-12
ATE141615T1 (en) 1996-09-15
EP0578521A1 (en) 1994-01-12
FR2692581A1 (en) 1993-12-24
DE69304155D1 (en) 1996-09-26
NZ247914A (en) 1994-12-22
ES2091570T3 (en) 1996-11-01
JPH0687891A (en) 1994-03-29
AU660809B2 (en) 1995-07-06
EP0578521B1 (en) 1996-08-21
DE69304155T2 (en) 1997-03-20
DK0578521T3 (en) 1996-12-09
FR2692581B1 (en) 1994-08-19
GR3021472T3 (en) 1997-01-31
CA2098655A1 (en) 1993-12-19
AU4128793A (en) 1993-12-23

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