ZA933494B - Xanthine phosphodiesterase inhibitors - Google Patents
Xanthine phosphodiesterase inhibitorsInfo
- Publication number
- ZA933494B ZA933494B ZA933494A ZA933494A ZA933494B ZA 933494 B ZA933494 B ZA 933494B ZA 933494 A ZA933494 A ZA 933494A ZA 933494 A ZA933494 A ZA 933494A ZA 933494 B ZA933494 B ZA 933494B
- Authority
- ZA
- South Africa
- Prior art keywords
- phosphodiesterase inhibitors
- xanthine phosphodiesterase
- xanthine
- inhibitors
- phosphodiesterase
- Prior art date
Links
- LRFVTYWOQMYALW-UHFFFAOYSA-N 9H-xanthine Chemical compound O=C1NC(=O)NC2=C1NC=N2 LRFVTYWOQMYALW-UHFFFAOYSA-N 0.000 title 2
- 229940082638 cardiac stimulant phosphodiesterase inhibitors Drugs 0.000 title 1
- 239000002571 phosphodiesterase inhibitor Substances 0.000 title 1
- 229940075420 xanthine Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
- C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB929210839A GB9210839D0 (en) | 1992-05-21 | 1992-05-21 | Novel compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA933494B true ZA933494B (en) | 1994-03-01 |
Family
ID=10715834
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA933494A ZA933494B (en) | 1992-05-21 | 1993-05-19 | Xanthine phosphodiesterase inhibitors |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP0641344A1 (cs) |
| JP (1) | JPH07506591A (cs) |
| CN (1) | CN1094046A (cs) |
| AU (1) | AU4081493A (cs) |
| CA (1) | CA2136196A1 (cs) |
| GB (1) | GB9210839D0 (cs) |
| MX (1) | MX9302957A (cs) |
| TW (1) | TW277062B (cs) |
| WO (1) | WO1993023401A1 (cs) |
| ZA (1) | ZA933494B (cs) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5684153A (en) | 1984-08-16 | 1997-11-04 | Beecham Group Plc | Process for the preparation of purine derivatives |
| GB9623859D0 (en) * | 1996-11-15 | 1997-01-08 | Chiroscience Ltd | Novel compounds |
| GB9703044D0 (en) | 1997-02-14 | 1997-04-02 | Glaxo Group Ltd | Phenyl xanthine esters and amides |
| KR100540046B1 (ko) | 1997-11-12 | 2006-01-10 | 미쓰비시 가가꾸 가부시키가이샤 | 퓨린유도체 및 이를 유효성분으로 함유하는 의약 |
| GB9817623D0 (en) | 1998-08-13 | 1998-10-07 | Glaxo Group Ltd | Pharmaceutical compounds |
| DE60006663T2 (de) * | 1999-05-11 | 2004-10-07 | Mitsubishi Chem Corp | Dihydrat eines purinderivates, medikamente die dieses als aktiven wirkstoff enthalten und zwischenprodukte zu dessen herstellung |
| US6403567B1 (en) | 1999-06-22 | 2002-06-11 | Cv Therapeutics, Inc. | N-pyrazole A2A adenosine receptor agonists |
| USRE47351E1 (en) | 1999-06-22 | 2019-04-16 | Gilead Sciences, Inc. | 2-(N-pyrazolo)adenosines with application as adenosine A2A receptor agonists |
| EP1208100B1 (en) * | 1999-08-31 | 2003-04-02 | Vanderbilt University | Selective antagonists of a2b adenosine receptors |
| US6815446B1 (en) | 1999-08-31 | 2004-11-09 | Vanderbilt University | Selective antagonists of A2B adenosine receptors |
| CA2671940A1 (en) | 2000-02-23 | 2001-08-30 | Cv Therapeutics, Inc. | Identification of partial agonists of the a2a adenosine receptor |
| US6821978B2 (en) | 2000-09-19 | 2004-11-23 | Schering Corporation | Xanthine phosphodiesterase V inhibitors |
| JP4450365B2 (ja) | 2001-08-28 | 2010-04-14 | シェーリング コーポレイション | 多環式グアニンホスホジエステラーゼｖ阻害剤 |
| US6943171B2 (en) | 2001-11-09 | 2005-09-13 | Schering Corporation | Polycyclic guanine derivative phosphodiesterase V inhibitors |
| EP1719772A1 (en) | 2002-05-31 | 2006-11-08 | Schering Corporation | Process for preparing xanthine phosphodiesterase v inhibitors and precursors thereof |
| EP1521584A1 (en) | 2002-06-17 | 2005-04-13 | Glaxo Group Limited | Purine derivatives as liver x receptor agonists |
| US20050020915A1 (en) | 2002-07-29 | 2005-01-27 | Cv Therapeutics, Inc. | Myocardial perfusion imaging methods and compositions |
| MXPA05001123A (es) | 2002-07-29 | 2005-04-29 | Cv Therapeutics Inc | Formacion de imagenes por perfusion de miocardio mediante el uso de agonistas receptores de a2a. |
| US8470801B2 (en) | 2002-07-29 | 2013-06-25 | Gilead Sciences, Inc. | Myocardial perfusion imaging methods and compositions |
| WO2005012303A1 (en) * | 2003-07-31 | 2005-02-10 | Schering Corporation | Metabolite of xanthine phosphodiesterase 5 inhibitor and derivatives thereof useful for treatment of erectile dysfunction |
| AU2005295437B2 (en) | 2004-10-20 | 2011-05-19 | Gilead Palo Alto, Inc. | Use of A2A adenosine receptor agonists |
| US7732595B2 (en) | 2006-02-03 | 2010-06-08 | Gilead Palo Alto, Inc. | Process for preparing an A2A-adenosine receptor agonist and its polymorphs |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0258191B1 (en) * | 1986-08-28 | 1992-05-27 | Sandoz Ag | Xanthine derivatives |
| IT1229195B (it) * | 1989-03-10 | 1991-07-25 | Poli Ind Chimica Spa | Derivati xantinici ad attivita' broncodilatatrice e loro applicazioni terapeutiche. |
| GB8906792D0 (en) * | 1989-03-23 | 1989-05-10 | Beecham Wuelfing Gmbh & Co Kg | Treatment and compounds |
| GB9020959D0 (en) * | 1990-09-26 | 1990-11-07 | Beecham Group Plc | Novel compounds |
| GB9020921D0 (en) * | 1990-09-26 | 1990-11-07 | Beecham Group Plc | Novel compounds |
| EP0563168B1 (en) * | 1990-12-21 | 2000-07-05 | Beecham Group Plc | Xanthine derivatives |
-
1992
- 1992-05-21 GB GB929210839A patent/GB9210839D0/en active Pending
-
1993
- 1993-05-18 CA CA002136196A patent/CA2136196A1/en not_active Abandoned
- 1993-05-18 WO PCT/GB1993/001014 patent/WO1993023401A1/en not_active Application Discontinuation
- 1993-05-18 AU AU40814/93A patent/AU4081493A/en not_active Abandoned
- 1993-05-18 JP JP5520016A patent/JPH07506591A/ja active Pending
- 1993-05-18 EP EP93910221A patent/EP0641344A1/en not_active Withdrawn
- 1993-05-19 ZA ZA933494A patent/ZA933494B/xx unknown
- 1993-05-20 CN CN93107586A patent/CN1094046A/zh active Pending
- 1993-05-20 MX MX9302957A patent/MX9302957A/es unknown
- 1993-06-03 TW TW082104444A patent/TW277062B/zh active
Also Published As
| Publication number | Publication date |
|---|---|
| MX9302957A (es) | 1994-05-31 |
| EP0641344A1 (en) | 1995-03-08 |
| WO1993023401A1 (en) | 1993-11-25 |
| AU4081493A (en) | 1993-12-13 |
| TW277062B (cs) | 1996-06-01 |
| GB9210839D0 (en) | 1992-07-08 |
| CN1094046A (zh) | 1994-10-26 |
| JPH07506591A (ja) | 1995-07-20 |
| CA2136196A1 (en) | 1993-11-25 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ZA933494B (en) | Xanthine phosphodiesterase inhibitors | |
| IL106532A0 (en) | Substituted nitrogen-containing heterocycles | |
| IL122923A0 (en) | Cyclic gmp-specific phosphodiesterase inhibitors | |
| ZA917610B (en) | Xanthine derivatives | |
| EP0682519A4 (en) | ADENOSINE KINAS INHIBITORS. | |
| GB9116684D0 (en) | Corrosion inhibitors | |
| IL108075A0 (en) | Enzyme inhibitors | |
| ZA925051B (en) | Corrosion inhibitors | |
| AU3192289A (en) | Nucleosidetype compounds which are phosphodiesterase inhibitors | |
| PL309610A1 (en) | Purine derivatives | |
| EP0501379A3 (en) | Xanthine compounds | |
| ZA931876B (en) | 2-Oxoquinoline derivatives | |
| HU9501397D0 (en) | Xanthine derivatives for use as diuretics | |
| ZA934970B (en) | Enzyme inhibitors | |
| GB2266760B (en) | Detonator | |
| GB2270913B (en) | Chlordifluoromethoxyphenyl derivatives | |
| GB2271564B (en) | Thioalkylthio carbacephalosporin derivatives | |
| EP0429038A3 (en) | Xanthine oxidase inhibitor | |
| EP0556778A3 (en) | Xanthine derivatives | |
| EP0543936A4 (en) | Renin inhibitors | |
| GB9303051D0 (en) | 17b-nmonosubstituted carbamoyl-11-oxo-4-aza-5-a-androst-en-3-one testosterone-5-alpha reductase inhibitors | |
| GB2268741B (en) | Pyrimidine compounds | |
| GB9301388D0 (en) | Lathe | |
| EP0565961A3 (en) | Ethyl-triazolyl derivatives | |
| ZA935762B (en) | Asymmetrically substituted xanthines |