ZA933494B - Xanthine phosphodiesterase inhibitors - Google Patents

Xanthine phosphodiesterase inhibitors

Info

Publication number
ZA933494B
ZA933494B ZA933494A ZA933494A ZA933494B ZA 933494 B ZA933494 B ZA 933494B ZA 933494 A ZA933494 A ZA 933494A ZA 933494 A ZA933494 A ZA 933494A ZA 933494 B ZA933494 B ZA 933494B
Authority
ZA
South Africa
Prior art keywords
phosphodiesterase inhibitors
xanthine phosphodiesterase
xanthine
inhibitors
phosphodiesterase
Prior art date
Application number
ZA933494A
Other languages
English (en)
Inventor
Ashley Edward Fenwick
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of ZA933494B publication Critical patent/ZA933494B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems
    • C07D473/02Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ZA933494A 1992-05-21 1993-05-19 Xanthine phosphodiesterase inhibitors ZA933494B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB929210839A GB9210839D0 (en) 1992-05-21 1992-05-21 Novel compounds

Publications (1)

Publication Number Publication Date
ZA933494B true ZA933494B (en) 1994-03-01

Family

ID=10715834

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA933494A ZA933494B (en) 1992-05-21 1993-05-19 Xanthine phosphodiesterase inhibitors

Country Status (10)

Country Link
EP (1) EP0641344A1 (cg-RX-API-DMAC10.html)
JP (1) JPH07506591A (cg-RX-API-DMAC10.html)
CN (1) CN1094046A (cg-RX-API-DMAC10.html)
AU (1) AU4081493A (cg-RX-API-DMAC10.html)
CA (1) CA2136196A1 (cg-RX-API-DMAC10.html)
GB (1) GB9210839D0 (cg-RX-API-DMAC10.html)
MX (1) MX9302957A (cg-RX-API-DMAC10.html)
TW (1) TW277062B (cg-RX-API-DMAC10.html)
WO (1) WO1993023401A1 (cg-RX-API-DMAC10.html)
ZA (1) ZA933494B (cg-RX-API-DMAC10.html)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5684153A (en) 1984-08-16 1997-11-04 Beecham Group Plc Process for the preparation of purine derivatives
GB9623859D0 (en) * 1996-11-15 1997-01-08 Chiroscience Ltd Novel compounds
GB9703044D0 (en) 1997-02-14 1997-04-02 Glaxo Group Ltd Phenyl xanthine esters and amides
WO1999024432A1 (fr) 1997-11-12 1999-05-20 Mitsubishi Chemical Corporation Derives de purine et medicament les renfermant en tant qu'ingredient actif
GB9817623D0 (en) 1998-08-13 1998-10-07 Glaxo Group Ltd Pharmaceutical compounds
AU4319000A (en) 1999-05-11 2000-11-21 Mitsubishi Chemical Corporation Purine derivative dihydrate, drugs containing the same as the active ingredient and intermediate in the production thereof
US6403567B1 (en) 1999-06-22 2002-06-11 Cv Therapeutics, Inc. N-pyrazole A2A adenosine receptor agonists
USRE47351E1 (en) 1999-06-22 2019-04-16 Gilead Sciences, Inc. 2-(N-pyrazolo)adenosines with application as adenosine A2A receptor agonists
HK1049835B (zh) * 1999-08-31 2005-04-08 范德比尔特大学 A2b腺苷受体的选择性拮抗剂
US6815446B1 (en) 1999-08-31 2004-11-09 Vanderbilt University Selective antagonists of A2B adenosine receptors
WO2001062979A2 (en) 2000-02-23 2001-08-30 Cv Therapeutics, Inc. Dentification of partial agonists of the a2a adenosine receptor
US6821978B2 (en) 2000-09-19 2004-11-23 Schering Corporation Xanthine phosphodiesterase V inhibitors
CA2457944C (en) 2001-08-28 2009-09-29 Schering Corporation Polycyclic guanine phosphodiesterase v inhibitors
JP2005509038A (ja) 2001-11-09 2005-04-07 シェーリング コーポレイション 多環式グアニン誘導体ホスホジエステラーゼv阻害剤
SI1509525T1 (sl) 2002-05-31 2006-12-31 Schering Corp Postopek priprave inhibitorjev ksantinske fosfodiesteraze V in njihovih prekurzorjev
JP4491344B2 (ja) 2002-06-17 2010-06-30 グラクソ グループ リミテッド 肝x受容体アゴニストとしてのプリン誘導体
US20050020915A1 (en) 2002-07-29 2005-01-27 Cv Therapeutics, Inc. Myocardial perfusion imaging methods and compositions
US8470801B2 (en) 2002-07-29 2013-06-25 Gilead Sciences, Inc. Myocardial perfusion imaging methods and compositions
US7683037B2 (en) 2002-07-29 2010-03-23 Gilead Palo Alto, Inc. Myocardial perfusion imaging method
JP2007500714A (ja) 2003-07-31 2007-01-18 シェーリング コーポレイション 勃起不全を処置するのに有用なキサンチンホスホジエステラーゼ5インヒビターの代謝物およびそれらの誘導体
CA2583185A1 (en) 2004-10-20 2006-04-27 Cv Therapeutics, Inc. Use of a2a adenosine receptor agonists
KR20080090491A (ko) 2006-02-03 2008-10-08 씨브이 쎄러퓨틱스, 인코포레이티드 A2a-아데노신 수용체 효능제 및 이의 다형체의 제조 방법

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0258191B1 (en) * 1986-08-28 1992-05-27 Sandoz Ag Xanthine derivatives
IT1229195B (it) * 1989-03-10 1991-07-25 Poli Ind Chimica Spa Derivati xantinici ad attivita' broncodilatatrice e loro applicazioni terapeutiche.
GB8906792D0 (en) * 1989-03-23 1989-05-10 Beecham Wuelfing Gmbh & Co Kg Treatment and compounds
GB9020959D0 (en) * 1990-09-26 1990-11-07 Beecham Group Plc Novel compounds
GB9020921D0 (en) * 1990-09-26 1990-11-07 Beecham Group Plc Novel compounds
DE69132291T2 (de) * 1990-12-21 2000-12-14 Beecham Group P.L.C., Brentford Xanthinderivate

Also Published As

Publication number Publication date
MX9302957A (es) 1994-05-31
JPH07506591A (ja) 1995-07-20
GB9210839D0 (en) 1992-07-08
CN1094046A (zh) 1994-10-26
AU4081493A (en) 1993-12-13
EP0641344A1 (en) 1995-03-08
TW277062B (cg-RX-API-DMAC10.html) 1996-06-01
CA2136196A1 (en) 1993-11-25
WO1993023401A1 (en) 1993-11-25

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