ZA927429B - Cardioprotective tocopherol analogs. - Google Patents
Cardioprotective tocopherol analogs.Info
- Publication number
- ZA927429B ZA927429B ZA927429A ZA927429A ZA927429B ZA 927429 B ZA927429 B ZA 927429B ZA 927429 A ZA927429 A ZA 927429A ZA 927429 A ZA927429 A ZA 927429A ZA 927429 B ZA927429 B ZA 927429B
- Authority
- ZA
- South Africa
- Prior art keywords
- cardioprotective
- tocopherol analogs
- tocopherol
- analogs
- benzopyrans
- Prior art date
Links
- 230000003293 cardioprotective effect Effects 0.000 title abstract 2
- 150000003611 tocopherol derivatives Chemical class 0.000 title 1
- 150000000463 2H-chromenes Chemical class 0.000 abstract 1
- 229940123457 Free radical scavenger Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 239000002516 radical scavenger Substances 0.000 abstract 1
- 229940124597 therapeutic agent Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
- C07F9/6552—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a six-membered ring
- C07F9/65522—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a six-membered ring condensed with carbocyclic rings or carbocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrane Compounds (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Inspection Of Paper Currency And Valuable Securities (AREA)
- Cosmetics (AREA)
- Polyesters Or Polycarbonates (AREA)
- Noodles (AREA)
- Credit Cards Or The Like (AREA)
- Absorbent Articles And Supports Therefor (AREA)
- Fire-Detection Mechanisms (AREA)
- Medicines Containing Plant Substances (AREA)
- Photoreceptors In Electrophotography (AREA)
- Saccharide Compounds (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP91402630A EP0535283A1 (en) | 1991-10-02 | 1991-10-02 | Cardioprotective tocopherol analogs |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA927429B true ZA927429B (en) | 1993-04-07 |
Family
ID=8208620
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA927429A ZA927429B (en) | 1991-10-02 | 1992-09-28 | Cardioprotective tocopherol analogs. |
Country Status (17)
| Country | Link |
|---|---|
| EP (2) | EP0535283A1 (OSRAM) |
| JP (1) | JP3230699B2 (OSRAM) |
| KR (1) | KR100253108B1 (OSRAM) |
| AT (1) | ATE163421T1 (OSRAM) |
| AU (1) | AU652077B2 (OSRAM) |
| CA (1) | CA2079289C (OSRAM) |
| DE (1) | DE69224501T2 (OSRAM) |
| DK (1) | DK0536036T3 (OSRAM) |
| ES (1) | ES2115656T3 (OSRAM) |
| FI (1) | FI105552B (OSRAM) |
| GR (1) | GR3026242T3 (OSRAM) |
| HU (1) | HU215123B (OSRAM) |
| IL (1) | IL103305A0 (OSRAM) |
| NO (1) | NO923840L (OSRAM) |
| NZ (1) | NZ244549A (OSRAM) |
| TW (1) | TW224970B (OSRAM) |
| ZA (1) | ZA927429B (OSRAM) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5721233A (en) * | 1992-04-06 | 1998-02-24 | Merrell Pharmaceuticals Inc. | Derivatives of 2,3-dihydro benzofuranols |
| US5510373A (en) * | 1992-04-06 | 1996-04-23 | Merrell Pharmaceuticals Inc. | Cardioprotective agents |
| US5545660A (en) * | 1992-04-07 | 1996-08-13 | Merrell Pharmaceuticals Inc. | Hydrazide derivatives of 3,4-dihydro-2H-1-benzopyrans |
| ATE296305T1 (de) * | 1997-11-25 | 2005-06-15 | Antipodean Biotechnology Ltd | Antioxidantien mit spezifischer wirkung auf mitochondrien |
| AUPR549901A0 (en) | 2001-06-06 | 2001-07-12 | Vital Health Sciences Pty Ltd | Topical formulation containing tocopheryl phosphates |
| JP4745608B2 (ja) | 2001-07-27 | 2011-08-10 | バイタル ヘルス サイエンシズ プロプライアタリー リミティド | 電子伝達剤のリン酸誘導体を用いた皮膚治療 |
| ATE409489T1 (de) * | 2002-06-19 | 2008-10-15 | Cognis Ip Man Gmbh | Verwendung von wirkstoffgemischen zur herstellung eines medikamentes gegen rheumatische arthritis |
| AU2002950713A0 (en) | 2002-08-09 | 2002-09-12 | Vital Health Sciences Pty Ltd | Carrier |
| US7888334B2 (en) | 2003-08-22 | 2011-02-15 | Antipodean Pharmaceuticals, Inc. | Mitoquinone derivatives used as mitochondrially targeted antioxidants |
| JP4648319B2 (ja) | 2003-08-22 | 2011-03-09 | アンティポディーン ファーマシューティカルズ インコーポレイティド | ミトコンドリアを標的とする抗酸化剤として使用されるミトキノン誘導体 |
| US7470798B2 (en) | 2003-09-19 | 2008-12-30 | Edison Pharmaceuticals, Inc. | 7,8-bicycloalkyl-chroman derivatives |
| NZ549567A (en) | 2004-03-03 | 2009-10-30 | Vital Health Sciences Pty Ltd | Formulations comprising a tocopheryl phosphate tertiary amine alkaloid complex |
| ES2557475T3 (es) | 2005-06-17 | 2016-01-26 | Vital Health Sciences Pty Ltd. | Un portador que comprende uno o más derivados di- y/o monofosfato de agentes de transferencia de electrones |
| US7813042B2 (en) | 2005-09-12 | 2010-10-12 | Sharp Kabushiki Kaisha | Multiple-view directional display |
| CN101512415B (zh) | 2006-09-07 | 2012-06-06 | 夏普株式会社 | 图像显示装置、电子设备和视差屏障元件 |
| US10071030B2 (en) | 2010-02-05 | 2018-09-11 | Phosphagenics Limited | Carrier comprising non-neutralised tocopheryl phosphate |
| ES2829386T3 (es) | 2010-03-30 | 2021-05-31 | Phosphagenics Ltd | Parche de administración transdérmica |
| EP2685992A4 (en) | 2011-03-15 | 2014-09-10 | Phosphagenics Ltd | AMINOCHINOLINE AS A KINASEHEMMER |
| ES2981002T3 (es) | 2015-12-09 | 2024-10-04 | Avecho Biotechnology Ltd | Formulación farmacéutica |
| JP7198754B2 (ja) | 2016-12-21 | 2023-01-04 | アベーチョ バイオテクノロジー リミテッド | 方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS62205091A (ja) * | 1986-03-04 | 1987-09-09 | Senjiyu Seiyaku Kk | 新規なリン酸ジエステルならびにその塩、その製造法およびそれを含有する製剤 |
| CA2002649C (en) * | 1988-11-14 | 2000-06-06 | Margaret Petty | Cardioprotective tocopherol analogs |
| US5500444A (en) | 1989-11-14 | 1996-03-19 | Hoechst Marion Roussel, Inc. | Cardioprotective tocopherol analogs |
| US5135945A (en) | 1991-06-05 | 1992-08-04 | Merrell Dow Pharmaceuticals Inc. | Cholesterol-lowering tocopherol analogs |
-
1991
- 1991-10-02 EP EP91402630A patent/EP0535283A1/en not_active Withdrawn
-
1992
- 1992-09-28 CA CA002079289A patent/CA2079289C/en not_active Expired - Fee Related
- 1992-09-28 AU AU25383/92A patent/AU652077B2/en not_active Ceased
- 1992-09-28 ZA ZA927429A patent/ZA927429B/xx unknown
- 1992-09-29 EP EP92402656A patent/EP0536036B1/en not_active Expired - Lifetime
- 1992-09-29 DE DE69224501T patent/DE69224501T2/de not_active Expired - Fee Related
- 1992-09-29 AT AT92402656T patent/ATE163421T1/de not_active IP Right Cessation
- 1992-09-29 NZ NZ24454992A patent/NZ244549A/en unknown
- 1992-09-29 DK DK92402656.0T patent/DK0536036T3/da active
- 1992-09-29 TW TW081107688A patent/TW224970B/zh active
- 1992-09-29 ES ES92402656T patent/ES2115656T3/es not_active Expired - Lifetime
- 1992-09-30 IL IL103305A patent/IL103305A0/xx unknown
- 1992-10-01 NO NO92923840A patent/NO923840L/no unknown
- 1992-10-01 HU HU9203134A patent/HU215123B/hu not_active IP Right Cessation
- 1992-10-01 KR KR1019920018013A patent/KR100253108B1/ko not_active Expired - Fee Related
- 1992-10-01 FI FI924424A patent/FI105552B/fi active
- 1992-10-02 JP JP28704592A patent/JP3230699B2/ja not_active Expired - Fee Related
-
1998
- 1998-02-26 GR GR980400390T patent/GR3026242T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP3230699B2 (ja) | 2001-11-19 |
| TW224970B (OSRAM) | 1994-06-11 |
| HU9203134D0 (en) | 1992-12-28 |
| DE69224501D1 (de) | 1998-04-02 |
| NZ244549A (en) | 1994-07-26 |
| HU215123B (hu) | 1998-09-28 |
| FI924424L (fi) | 1993-04-03 |
| AU652077B2 (en) | 1994-08-11 |
| FI105552B (fi) | 2000-09-15 |
| ES2115656T3 (es) | 1998-07-01 |
| GR3026242T3 (en) | 1998-05-29 |
| NO923840D0 (no) | 1992-10-01 |
| JPH05310763A (ja) | 1993-11-22 |
| IL103305A0 (en) | 1993-02-21 |
| DK0536036T3 (da) | 1998-03-16 |
| EP0535283A1 (en) | 1993-04-07 |
| NO923840L (no) | 1993-04-05 |
| CA2079289A1 (en) | 1993-04-03 |
| CA2079289C (en) | 2003-02-18 |
| DE69224501T2 (de) | 1998-06-25 |
| HUT62592A (en) | 1993-05-28 |
| EP0536036B1 (en) | 1998-02-25 |
| EP0536036A1 (en) | 1993-04-07 |
| AU2538392A (en) | 1993-04-08 |
| KR100253108B1 (ko) | 2000-05-01 |
| FI924424A0 (fi) | 1992-10-01 |
| ATE163421T1 (de) | 1998-03-15 |
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