ZA926828B - Novel alkoxy substituted taxanes and pharmaceutical compositions containing them. - Google Patents

Novel alkoxy substituted taxanes and pharmaceutical compositions containing them.

Info

Publication number
ZA926828B
ZA926828B ZA926828A ZA926828A ZA926828B ZA 926828 B ZA926828 B ZA 926828B ZA 926828 A ZA926828 A ZA 926828A ZA 926828 A ZA926828 A ZA 926828A ZA 926828 B ZA926828 B ZA 926828B
Authority
ZA
South Africa
Prior art keywords
pharmaceutical compositions
compositions containing
alkoxy substituted
substituted taxanes
novel alkoxy
Prior art date
Application number
ZA926828A
Inventor
Robert A Holton
Ronald J Biediger
Original Assignee
Univ Florida State
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Florida State filed Critical Univ Florida State
Publication of ZA926828B publication Critical patent/ZA926828B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/22—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from lactams, cyclic ketones or cyclic oximes, e.g. by reactions involving Beckmann rearrangement
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/64—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C233/81—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • C07C233/82—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C07C233/87—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom of a carbon skeleton containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic System
    • C07F7/003—Compounds containing elements of Groups 4 or 14 of the Periodic System without C-Metal linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic System
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/56—Ring systems containing bridged rings
    • C07C2603/58—Ring systems containing bridged rings containing three rings
    • C07C2603/60—Ring systems containing bridged rings containing three rings containing at least one ring with less than six members
    • C07C2603/62—Ring systems containing bridged rings containing three rings containing at least one ring with less than six members containing three- or four-membered rings
ZA926828A 1991-09-23 1992-09-08 Novel alkoxy substituted taxanes and pharmaceutical compositions containing them. ZA926828B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US76380591A 1991-09-23 1991-09-23

Publications (1)

Publication Number Publication Date
ZA926828B true ZA926828B (en) 1993-03-15

Family

ID=25068860

Family Applications (5)

Application Number Title Priority Date Filing Date
ZA926829A ZA926829B (en) 1991-09-23 1992-09-08 Novel substituted taxanes and pharmaceutical compositions containing them.
ZA926827A ZA926827B (en) 1991-09-23 1992-09-08 Novel furyl and thienyl substituted taxanes and pharmaceutical compositions containing them.
ZA926828A ZA926828B (en) 1991-09-23 1992-09-08 Novel alkoxy substituted taxanes and pharmaceutical compositions containing them.
ZA927039A ZA927039B (en) 1991-09-23 1992-09-15 Semi-synthesis of taxane derivatives using metal alkoxides and beta-lactams
ZA927038A ZA927038B (en) 1991-09-23 1992-09-15 Metal alkoxides.

Family Applications Before (2)

Application Number Title Priority Date Filing Date
ZA926829A ZA926829B (en) 1991-09-23 1992-09-08 Novel substituted taxanes and pharmaceutical compositions containing them.
ZA926827A ZA926827B (en) 1991-09-23 1992-09-08 Novel furyl and thienyl substituted taxanes and pharmaceutical compositions containing them.

Family Applications After (2)

Application Number Title Priority Date Filing Date
ZA927039A ZA927039B (en) 1991-09-23 1992-09-15 Semi-synthesis of taxane derivatives using metal alkoxides and beta-lactams
ZA927038A ZA927038B (en) 1991-09-23 1992-09-15 Metal alkoxides.

Country Status (3)

Country Link
AU (2) AU642391B3 (en)
RU (1) RU2114836C1 (en)
ZA (5) ZA926829B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5227400A (en) * 1991-09-23 1993-07-13 Florida State University Furyl and thienyl substituted taxanes and pharmaceutical compositions containing them
CA2100808A1 (en) * 1992-10-01 1994-04-02 Vittorio Farina Deoxy paclitaxels

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69217147T2 (en) * 1991-09-04 1997-06-05 Nec Corp Radio transceiver
US5243045A (en) * 1991-09-23 1993-09-07 Florida State University Certain alkoxy substituted taxanes and pharmaceutical compositions containing them
US5250683A (en) * 1991-09-23 1993-10-05 Florida State University Certain substituted taxanes and pharmaceutical compositions containing them
US5229526A (en) * 1991-09-23 1993-07-20 Florida State University Metal alkoxides

Also Published As

Publication number Publication date
ZA926827B (en) 1993-03-15
AU3983793A (en) 1993-08-19
ZA927039B (en) 1993-12-20
AU3983893A (en) 1993-08-19
ZA927038B (en) 1993-05-14
AU642391B3 (en) 1993-10-14
ZA926829B (en) 1993-03-15
AU642392B3 (en) 1993-10-14
RU2114836C1 (en) 1998-07-10

Similar Documents

Publication Publication Date Title
ZA94342B (en) C2 Taxane derivatives and pharmaceutical compositions containing them
NZ244766A (en) Bi-aromatic compounds and pharmaceutical compositions
ZA937321B (en) Taxol derivatives their preparation and compositions containing them
IL102638A0 (en) Heterocyclic compounds,their preparation and pharmaceutical compositions containing them
IL103053A0 (en) Heterocyclic compounds,their preparation and pharmaceutical compositions containing them
IL101763A0 (en) Dialkylenepiperidino compounds and their enantiomers,their preparation and pharmaceutical compositions containing them
IL101380A0 (en) Bis-naphthalimides,their preparation and pharmaceutical compositions containing them
IL99658A0 (en) Substituted azetidinones and pharmaceutical compositions containing them
IL102292A0 (en) Substituted azetidinones,their preparation and pharmaceutical compositions containing them
IL102337A0 (en) Pyrrolpyrazines,their manufacture and pharmaceutical compositions containing them
ZA937558B (en) New taxane derivatives, their preparation and pharmaceutical compositions which contain them
ZA941469B (en) C9 taxane derivatives and pharmaceutical compositions containing them
HU9601219D0 (en) Novel taxoids, their preparation and pharmaceutical compositions containing them
HU9303113D0 (en) Pharmaceutical compositions containing 1,2-dithiol-3-thione-derivatives
GB2251617B (en) Pharmaceutical compositions containing substituted 3-hydroxypyridin-4-ones
IL104042A0 (en) Substituted diphenylsulfides,their preparation and pharmaceutical compositions containing them
ZA933462B (en) New taxane derivative, their preparation and compositions containing them
IL102477A0 (en) Dithianes,their manufacture and pharmaceutical compositions containing them
IL101164A0 (en) Heterocyclic compounds,their preparation and pharmaceutical compositions containing them
IL103698A0 (en) Heterocyclic compounds,their preparation and pharmaceutical compositions containing them
IL101482A0 (en) Substituted 2',3'-dideoxy-5-trifluoromethyluridines,and pharmaceutical compositions containing them
ZA926828B (en) Novel alkoxy substituted taxanes and pharmaceutical compositions containing them.
IL103926A0 (en) Quinolylmethoxyphenyl-acetamides,their preparation and pharmaceutical compositions containing them
IL102666A0 (en) Quinolin-2-yl-methoxybenzyl-hydroxyureas,their preparation and pharmaceutical compositions containing them
IL101165A0 (en) Heterocyclic compounds,their preparation and pharmaceutical compositions containing them