ZA919297B - Stabilized hexahydro-pyrimidinamine compounds in aqueous solution and methods for preparing same - Google Patents

Stabilized hexahydro-pyrimidinamine compounds in aqueous solution and methods for preparing same

Info

Publication number
ZA919297B
ZA919297B ZA919297A ZA919297A ZA919297B ZA 919297 B ZA919297 B ZA 919297B ZA 919297 A ZA919297 A ZA 919297A ZA 919297 A ZA919297 A ZA 919297A ZA 919297 B ZA919297 B ZA 919297B
Authority
ZA
South Africa
Prior art keywords
hexahydro
stabilized
methods
aqueous solution
preparing same
Prior art date
Application number
ZA919297A
Other languages
English (en)
Inventor
Edward J Carlin
J Carlin Edward
Anil K Talwar
K Talwar Anil
Steven S Dills
S Dills Steven
Joseph M Talmage
M Talmage Joseph
Eugene C Samarco
C Samarco Eugene
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of ZA919297B publication Critical patent/ZA919297B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4953—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom containing pyrimidine ring derivatives, e.g. minoxidil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dermatology (AREA)
  • Birds (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
ZA919297A 1990-11-26 1991-11-25 Stabilized hexahydro-pyrimidinamine compounds in aqueous solution and methods for preparing same ZA919297B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US61772990A 1990-11-26 1990-11-26

Publications (1)

Publication Number Publication Date
ZA919297B true ZA919297B (en) 1992-08-26

Family

ID=24474821

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA919297A ZA919297B (en) 1990-11-26 1991-11-25 Stabilized hexahydro-pyrimidinamine compounds in aqueous solution and methods for preparing same

Country Status (6)

Country Link
EP (1) EP0512104A1 (fr)
CA (1) CA2074484A1 (fr)
MX (1) MX9102200A (fr)
NZ (1) NZ240695A (fr)
WO (1) WO1992009283A1 (fr)
ZA (1) ZA919297B (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5496558A (en) * 1993-03-02 1996-03-05 Block Drug Company Inc. Solid form xerostomia product
EP1029543B1 (fr) * 1999-02-19 2002-11-20 Warner-Lambert Company Préparation thérapeutique aqueuse contenant un composé pyrimidinamine-5-hexahydro et un alcool gras polyalkoxylé
US7893223B2 (en) 2001-07-17 2011-02-22 Bracco Imaging S.P.A. Multidentate AZA ligands able to complex metal ions and the use thereof in diagnostics and therapy
ITMI20011518A1 (it) * 2001-07-17 2003-01-17 Bracco Imaging Spa Leganti azotati multidentati capaci di complessare ioni metallici e loro uso in diagnostica e in terapia

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4666517A (en) * 1986-06-04 1987-05-19 Colgate-Palmolive Co. Antiplaque oral composition
US4774078A (en) * 1986-10-06 1988-09-27 Colgate-Palmolive Company Stable antiplaque dentifrice based on hexetidine, zinc ion and fluoride
US4992276A (en) * 1988-12-14 1991-02-12 Warner-Lambert Company Antiseptic compositions containing hexahydro-5-pyrimidinamine compounds and thymol and methods for preparing same
EP0408174A1 (fr) * 1989-07-12 1991-01-16 Warner-Lambert Company Composition antiseptique contenant des composés de hexahydro-5-pyrimidinamine
GB9008433D0 (en) * 1990-04-12 1990-06-13 Beecham Group Plc Novel compositions
FR2661091B1 (fr) * 1990-04-18 1994-10-21 Andre Salkin Utilisation de l'hexetidine ou de ses derives ou sels pour la preparation d'une composition pharmaceutique a usage ophtalmologique.

Also Published As

Publication number Publication date
NZ240695A (en) 1993-10-26
CA2074484A1 (fr) 1992-05-27
MX9102200A (es) 1992-07-08
EP0512104A1 (fr) 1992-11-11
WO1992009283A1 (fr) 1992-06-11

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