ZA919297B - Stabilized hexahydro-pyrimidinamine compounds in aqueous solution and methods for preparing same - Google Patents

Stabilized hexahydro-pyrimidinamine compounds in aqueous solution and methods for preparing same

Info

Publication number
ZA919297B
ZA919297B ZA919297A ZA919297A ZA919297B ZA 919297 B ZA919297 B ZA 919297B ZA 919297 A ZA919297 A ZA 919297A ZA 919297 A ZA919297 A ZA 919297A ZA 919297 B ZA919297 B ZA 919297B
Authority
ZA
South Africa
Prior art keywords
hexahydro
stabilized
methods
aqueous solution
preparing same
Prior art date
Application number
ZA919297A
Inventor
Edward J Carlin
J Carlin Edward
Anil K Talwar
K Talwar Anil
Steven S Dills
S Dills Steven
Joseph M Talmage
M Talmage Joseph
Eugene C Samarco
C Samarco Eugene
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of ZA919297B publication Critical patent/ZA919297B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4953—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom containing pyrimidine ring derivatives, e.g. minoxidil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Birds (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
ZA919297A 1990-11-26 1991-11-25 Stabilized hexahydro-pyrimidinamine compounds in aqueous solution and methods for preparing same ZA919297B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US61772990A 1990-11-26 1990-11-26

Publications (1)

Publication Number Publication Date
ZA919297B true ZA919297B (en) 1992-08-26

Family

ID=24474821

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA919297A ZA919297B (en) 1990-11-26 1991-11-25 Stabilized hexahydro-pyrimidinamine compounds in aqueous solution and methods for preparing same

Country Status (6)

Country Link
EP (1) EP0512104A1 (en)
CA (1) CA2074484A1 (en)
MX (1) MX9102200A (en)
NZ (1) NZ240695A (en)
WO (1) WO1992009283A1 (en)
ZA (1) ZA919297B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5496558A (en) * 1993-03-02 1996-03-05 Block Drug Company Inc. Solid form xerostomia product
ATE227990T1 (en) 1999-02-19 2002-12-15 Warner Lambert Co THERAPEUTIC AQUEOUS COMPOSITION CONTAINING A HEXAHYDRO-5-PYRIMIDINAMINE DERIVATIVE AND A POLYALKOXYLATED FAT ALCOHOL
ITMI20011518A1 (en) * 2001-07-17 2003-01-17 Bracco Imaging Spa MULTIDENTATED NITROGEN BINDERS CAPABLE OF COMPLEXING METAL IONS AND THEIR USE IN DIAGNOSTICS AND THERAPY
US7893223B2 (en) 2001-07-17 2011-02-22 Bracco Imaging S.P.A. Multidentate AZA ligands able to complex metal ions and the use thereof in diagnostics and therapy

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4666517A (en) * 1986-06-04 1987-05-19 Colgate-Palmolive Co. Antiplaque oral composition
US4774078A (en) * 1986-10-06 1988-09-27 Colgate-Palmolive Company Stable antiplaque dentifrice based on hexetidine, zinc ion and fluoride
US4992276A (en) * 1988-12-14 1991-02-12 Warner-Lambert Company Antiseptic compositions containing hexahydro-5-pyrimidinamine compounds and thymol and methods for preparing same
EP0408174A1 (en) * 1989-07-12 1991-01-16 Warner-Lambert Company Antiseptic composition containing hexahydro-5-pyrimidinamine compounds
GB9008433D0 (en) * 1990-04-12 1990-06-13 Beecham Group Plc Novel compositions
FR2661091B1 (en) * 1990-04-18 1994-10-21 Andre Salkin USE OF HEXETIDINE OR ITS DERIVATIVES OR SALTS FOR THE PREPARATION OF A PHARMACEUTICAL COMPOSITION FOR OPHTHALMOLOGICAL USE.

Also Published As

Publication number Publication date
EP0512104A1 (en) 1992-11-11
NZ240695A (en) 1993-10-26
WO1992009283A1 (en) 1992-06-11
MX9102200A (en) 1992-07-08
CA2074484A1 (en) 1992-05-27

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