ZA918717B - Cyclopeptides - Google Patents

Cyclopeptides

Info

Publication number
ZA918717B
ZA918717B ZA918717A ZA918717A ZA918717B ZA 918717 B ZA918717 B ZA 918717B ZA 918717 A ZA918717 A ZA 918717A ZA 918717 A ZA918717 A ZA 918717A ZA 918717 B ZA918717 B ZA 918717B
Authority
ZA
South Africa
Prior art keywords
cyclopeptides
Prior art date
Application number
ZA918717A
Inventor
Gunter Holzemann
Holzemann Gunter
Alfred Jonczyk
Jonczyk Alfred
Jurgen Harting
Harting Jurgen
Hartmut Greiner
Greiner Hartmut
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of ZA918717B publication Critical patent/ZA918717B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/22—Tachykinins, e.g. Eledoisins, Substance P; Related peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/52—Cyclic peptides containing at least one abnormal peptide link with only normal peptide links in the ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Pain & Pain Management (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
ZA918717A 1990-11-02 1991-11-01 Cyclopeptides ZA918717B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4034829A DE4034829A1 (en) 1990-11-02 1990-11-02 CYCLOPEPTIDE

Publications (1)

Publication Number Publication Date
ZA918717B true ZA918717B (en) 1992-08-26

Family

ID=6417499

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA918717A ZA918717B (en) 1990-11-02 1991-11-01 Cyclopeptides

Country Status (11)

Country Link
EP (1) EP0484719A3 (en)
JP (1) JPH04300895A (en)
KR (1) KR920009846A (en)
AU (1) AU8676291A (en)
CA (1) CA2054667A1 (en)
CS (1) CS331491A3 (en)
DE (1) DE4034829A1 (en)
HU (1) HUT61582A (en)
IE (1) IE913831A1 (en)
PT (1) PT99384A (en)
ZA (1) ZA918717B (en)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT533280E (en) 1991-09-20 2001-01-31 Glaxo Group Ltd NEW MEDICAL USES FOR TACHYKININE ANTAGONISTS
GB9702377D0 (en) * 1996-02-23 1997-03-26 Zeneca Ltd Peptide derivatives
PL330348A1 (en) 1996-06-07 1999-05-10 Zeneca Ltd Peptidic derivatives
GB9621836D0 (en) 1996-10-19 1996-12-11 Zeneca Ltd Peptide compounds
GB9624562D0 (en) 1996-11-27 1997-01-15 Zeneca Ltd Peptide derivatives
KR100408624B1 (en) * 2000-10-06 2003-12-06 엘지전선 주식회사 Poly vinyl chloride insulator composition for wire and cable
WO2008090117A1 (en) 2007-01-24 2008-07-31 Glaxo Group Limited Pharmaceutical compositions comprising 3, 5-diamin0-6- (2, 3-dichl0phenyl) -l, 2, 4-triazine or r (-) -2, 4-diamino-5- (2, 3-dichlorophenyl) -6-fluoromethyl pyrimidine and an nk1
UA105182C2 (en) 2008-07-03 2014-04-25 Ньюрексон, Інк. Benzoxazines, benzothiazines, and related compounds having nos inhibitory activity
US9446029B2 (en) 2010-07-27 2016-09-20 Colorado State University Research Foundation Use of NK-1 receptor antagonists in management of visceral pain
AU2012322085B2 (en) 2011-10-14 2017-05-04 Bristol-Myers Squibb Company Substituted tetrahydroisoquinoline compounds as factor Xia inhibitors
EP2766345B1 (en) 2011-10-14 2016-03-16 Bristol-Myers Squibb Company Substituted tetrahydroisoquinoline compounds as factor xia inhibitors
JP6033318B2 (en) 2011-10-14 2016-11-30 ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ Substituted tetrahydroisoquinoline compounds as factor XIa inhibitors
ES2668318T3 (en) 2012-10-12 2018-05-17 Bristol-Myers Squibb Company Crystal forms of factor XIa inhibitor
US9315519B2 (en) 2012-10-12 2016-04-19 Bristol-Myers Squibb Company Guanidine substituted tetrahydroisoquinoline compounds as factor XIa inhibitors
US9403774B2 (en) 2012-10-12 2016-08-02 Bristol-Myers Squibb Company Guanidine and amine substituted tetrahydroisoquinoline compounds as factor xia inhibitors
EP2978751B1 (en) 2013-03-25 2018-12-05 Bristol-Myers Squibb Company Tetrahydroisoquinolines containing substituted azoles as factor xia inhibitors
JP6464176B2 (en) 2014-01-31 2019-02-06 ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ Macrocycles as factor XIA inhibitors with aromatic P2 'groups
NO2760821T3 (en) 2014-01-31 2018-03-10
ES2714283T3 (en) 2014-09-04 2019-05-28 Bristol Myers Squibb Co Macrocycles of diamide that are inhibitors of FXIa
US9453018B2 (en) 2014-10-01 2016-09-27 Bristol-Myers Squibb Company Pyrimidinones as factor XIa inhibitors

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8807246D0 (en) * 1988-03-25 1988-04-27 Merck Sharp & Dohme Therapeutic agents
ZA906188B (en) * 1989-08-10 1991-06-26 Merrell Dow Pharma Cyclic neurokinin a antagonists

Also Published As

Publication number Publication date
CS331491A3 (en) 1992-05-13
PT99384A (en) 1992-09-30
JPH04300895A (en) 1992-10-23
HUT61582A (en) 1993-01-28
IE913831A1 (en) 1992-05-22
KR920009846A (en) 1992-06-25
AU8676291A (en) 1992-05-07
EP0484719A2 (en) 1992-05-13
HU913450D0 (en) 1992-01-28
EP0484719A3 (en) 1993-05-19
CA2054667A1 (en) 1992-05-03
DE4034829A1 (en) 1992-05-07

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