ZA914933B - Receptor directed-toxin conjugates - Google Patents
Receptor directed-toxin conjugatesInfo
- Publication number
- ZA914933B ZA914933B ZA914933A ZA914933A ZA914933B ZA 914933 B ZA914933 B ZA 914933B ZA 914933 A ZA914933 A ZA 914933A ZA 914933 A ZA914933 A ZA 914933A ZA 914933 B ZA914933 B ZA 914933B
- Authority
- ZA
- South Africa
- Prior art keywords
- toxin conjugates
- receptor directed
- receptor
- directed
- conjugates
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/642—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the peptide or protein in the drug conjugate being a cytokine, e.g. IL2, chemokine, growth factors or interferons being the inactive part of the conjugate
Landscapes
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP90201790 | 1990-07-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA914933B true ZA914933B (en) | 1992-04-29 |
Family
ID=8205057
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA914933A ZA914933B (en) | 1990-07-05 | 1991-06-26 | Receptor directed-toxin conjugates |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP0537229A1 (en) |
| JP (1) | JPH05508634A (en) |
| AU (1) | AU657910B2 (en) |
| CA (1) | CA2086679A1 (en) |
| IE (1) | IE912167A1 (en) |
| WO (1) | WO1992000762A1 (en) |
| ZA (1) | ZA914933B (en) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1992015318A1 (en) * | 1991-03-07 | 1992-09-17 | Seragen, Inc. | Use of cell surface receptor targeted molecules for the treatment of viral diseases |
| ATE311895T1 (en) * | 1992-05-26 | 2005-12-15 | Immunex Corp | NEW CYTOKINE THAT BINDS CD30 |
| US5536642A (en) * | 1993-09-09 | 1996-07-16 | Barbera-Guillem; Emilio | Diagnostic and prognostic methods for solid non-lymphoid tumors and their metastases |
| EP0831917A2 (en) * | 1995-06-07 | 1998-04-01 | Innogenetics N.V. | Immunotoxins specific for cd80 and cd86 expressing cells |
| DK0932417T3 (en) | 1996-10-17 | 2003-04-14 | Immunomedics Inc | Non-antigenic toxin conjugate and fusion protein of internalizing receptor system |
| JP2002509158A (en) * | 1998-01-15 | 2002-03-26 | センター・フォー・モレキュラー・メディシン・アンド・イムノロジー | Antibodies and receptor targeting moieties for improved delivery of armed ligands |
| US6703488B1 (en) | 1998-01-15 | 2004-03-09 | Center For Molecular Medicine And Immunology | Antibody/receptor targeting moiety for enhanced delivery of armed ligand |
| CA2921401A1 (en) | 2013-08-14 | 2015-02-19 | William Marsh Rice University | Derivatives of uncialamycin, methods of synthesis and their use as antitumor agents |
| US20230277682A1 (en) * | 2022-01-14 | 2023-09-07 | Regeneron Pharmaceuticals, Inc. | Verrucarin a derivatives and antibody drug conjugates thereof |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU6408586A (en) * | 1985-10-03 | 1987-04-24 | Biotechnology Research Partners Limited | Novel lipoprotein-based drug-delivery systems |
| IN165717B (en) * | 1986-08-07 | 1989-12-23 | Battelle Memorial Institute | |
| ZA888978B (en) * | 1987-12-04 | 1990-07-25 | Du Pont | Immobilized interleukin 2 and interleukin 2 containing a carboxylterminal extension |
| DE68917138T2 (en) * | 1988-05-19 | 1995-02-23 | Beth Israel Hospital | TOLERANCE INDUCTION TO A FOREIGNANT. |
| EP0378666A4 (en) * | 1988-07-05 | 1992-01-22 | Amgen Inc. | Interleukin ii analogs |
| US5149782A (en) * | 1988-08-19 | 1992-09-22 | Tanox Biosystems, Inc. | Molecular conjugates containing cell membrane-blending agents |
-
1991
- 1991-06-21 CA CA002086679A patent/CA2086679A1/en not_active Abandoned
- 1991-06-21 JP JP91511341A patent/JPH05508634A/en active Pending
- 1991-06-21 EP EP91912210A patent/EP0537229A1/en not_active Withdrawn
- 1991-06-21 AU AU80606/91A patent/AU657910B2/en not_active Ceased
- 1991-06-21 IE IE216791A patent/IE912167A1/en unknown
- 1991-06-21 WO PCT/EP1991/001169 patent/WO1992000762A1/en not_active Application Discontinuation
- 1991-06-26 ZA ZA914933A patent/ZA914933B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JPH05508634A (en) | 1993-12-02 |
| AU657910B2 (en) | 1995-03-30 |
| EP0537229A1 (en) | 1993-04-21 |
| IE912167A1 (en) | 1992-01-15 |
| CA2086679A1 (en) | 1992-01-06 |
| WO1992000762A1 (en) | 1992-01-23 |
| AU8060691A (en) | 1992-02-04 |
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