ZA91490B - Pyridylphenyl nitrogen heterocycle-substituted carbinols and derivatives thereof with anti-inflammatory activity - Google Patents

Pyridylphenyl nitrogen heterocycle-substituted carbinols and derivatives thereof with anti-inflammatory activity

Info

Publication number
ZA91490B
ZA91490B ZA91490A ZA91490A ZA91490B ZA 91490 B ZA91490 B ZA 91490B ZA 91490 A ZA91490 A ZA 91490A ZA 91490 A ZA91490 A ZA 91490A ZA 91490 B ZA91490 B ZA 91490B
Authority
ZA
South Africa
Prior art keywords
pyridylphenyl
derivatives
nitrogen heterocycle
inflammatory activity
substituted carbinols
Prior art date
Application number
ZA91490A
Other languages
English (en)
Inventor
Douglas Guy Batt
Guy Batt Douglas
Stephen Wayne Wright
Wayne Wright Stephen
Original Assignee
Du Pont
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont filed Critical Du Pont
Publication of ZA91490B publication Critical patent/ZA91490B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/10Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
ZA91490A 1990-01-23 1991-01-23 Pyridylphenyl nitrogen heterocycle-substituted carbinols and derivatives thereof with anti-inflammatory activity ZA91490B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/469,854 US5049570A (en) 1990-01-23 1990-01-23 Pyridylphenyl nitrogen heterocycle-substituted carbinols and derivatives thereof with anti-inflammatory activity

Publications (1)

Publication Number Publication Date
ZA91490B true ZA91490B (en) 1992-09-30

Family

ID=23865295

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA91490A ZA91490B (en) 1990-01-23 1991-01-23 Pyridylphenyl nitrogen heterocycle-substituted carbinols and derivatives thereof with anti-inflammatory activity

Country Status (15)

Country Link
US (1) US5049570A (xx)
EP (1) EP0513149B1 (xx)
JP (1) JP3053428B2 (xx)
KR (1) KR927003575A (xx)
AT (1) ATE131475T1 (xx)
AU (1) AU632905B2 (xx)
CA (1) CA2074723C (xx)
DE (1) DE69115468T2 (xx)
GR (1) GR3019121T3 (xx)
HK (1) HK1006840A1 (xx)
IE (1) IE910207A1 (xx)
IL (1) IL97007A0 (xx)
NZ (1) NZ236850A (xx)
WO (1) WO1991011445A1 (xx)
ZA (1) ZA91490B (xx)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ270418A (en) * 1994-02-07 1997-09-22 Eisai Co Ltd Polycyclic triazole & imidazole derivatives, antifungal compositions
US6265584B1 (en) * 1998-05-22 2001-07-24 Bristol-Myers Squibb Company Water soluble prodrugs of azole compounds
KR101164258B1 (ko) 2003-12-23 2012-07-11 아스텍스 테라퓨틱스 리미티드 단백질 키나아제 조절제로서의 피라졸 유도체
EP1751136B1 (en) * 2004-05-07 2014-07-02 Amgen Inc. Nitrogenated heterocyclic derivatives as protein kinase modulators and use for the treatment of angiogenesis and cancer
WO2006136823A1 (en) * 2005-06-21 2006-12-28 Astex Therapeutics Limited Heterocyclic containing amines as kinase b inhibitors
WO2006136821A1 (en) 2005-06-22 2006-12-28 Astex Therapeutics Limited Pharmaceutical compounds
US8541461B2 (en) 2005-06-23 2013-09-24 Astex Therapeutics Limited Pharmaceutical combinations comprising pyrazole derivatives as protein kinase modulators
GB0704932D0 (en) 2007-03-14 2007-04-25 Astex Therapeutics Ltd Pharmaceutical compounds
JP6507165B2 (ja) 2013-12-05 2019-04-24 バイエル・クロップサイエンス・アクチェンゲゼルシャフト N−シクロアルキル−n−{[2−(1−置換シクロアルキル)フェニル]メチレン}−(チオ)カルボキサミド誘導体
WO2015082587A1 (en) 2013-12-05 2015-06-11 Bayer Cropscience Ag N-cycloalkyl-n-{[2-(1-substitutedcycloalkyl)phenyl]methylene}-(thio)carboxamide derivatives

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2732750A1 (de) * 1977-07-20 1979-02-08 Merck Patent Gmbh Basische thioaether und verfahren zu ihrer herstellung
DE2851116A1 (de) * 1978-11-25 1980-06-12 Bayer Ag Hydroxyethyl-azole, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
DE2920375A1 (de) * 1979-05-19 1980-11-20 Bayer Ag Fungizide mittel, verfahren zu ihrer herstellung sowie ihre verwendung als fungizide
DE2920374A1 (de) * 1979-05-19 1980-11-20 Bayer Ag Fungizide mittel, verfahren zu ihrer herstellung sowie ihre verwendung als fungizide
DE3345813A1 (de) * 1983-12-17 1985-06-27 Boehringer Ingelheim KG, 6507 Ingelheim Neue 2-(1-imidazolyl)-ethanol-derivate
DE3413173A1 (de) * 1984-04-07 1985-10-17 Bayer Ag, 5090 Leverkusen (1,2,4-triazol-1-yl)-methyl-carbinole
DE3813841A1 (de) * 1987-06-03 1988-12-15 Bayer Ag Heterocyclische hydroxyethylazole
US4859693A (en) * 1988-08-10 1989-08-22 E. I. Du Pont De Nemours And Company Antiinflammatory carbinoloimidazoles

Also Published As

Publication number Publication date
KR927003575A (ko) 1992-12-18
AU7222891A (en) 1991-08-21
WO1991011445A1 (en) 1991-08-08
EP0513149B1 (en) 1995-12-13
IL97007A0 (en) 1992-03-29
IE910207A1 (en) 1991-07-31
CA2074723C (en) 2001-10-30
ATE131475T1 (de) 1995-12-15
DE69115468T2 (de) 1996-05-23
JPH05507904A (ja) 1993-11-11
JP3053428B2 (ja) 2000-06-19
DE69115468D1 (de) 1996-01-25
NZ236850A (en) 1994-01-26
AU632905B2 (en) 1993-01-14
GR3019121T3 (en) 1996-05-31
EP0513149A1 (en) 1992-11-19
CA2074723A1 (en) 1991-07-24
US5049570A (en) 1991-09-17
HK1006840A1 (en) 1999-03-19

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