ZA913879B - Synergistic tumor therapy with combinations of biologically active anti-tumor antibodies and chemotherapy - Google Patents
Synergistic tumor therapy with combinations of biologically active anti-tumor antibodies and chemotherapyInfo
- Publication number
- ZA913879B ZA913879B ZA913879A ZA913879A ZA913879B ZA 913879 B ZA913879 B ZA 913879B ZA 913879 A ZA913879 A ZA 913879A ZA 913879 A ZA913879 A ZA 913879A ZA 913879 B ZA913879 B ZA 913879B
- Authority
- ZA
- South Africa
- Prior art keywords
- tumor
- chemotherapy
- combinations
- biologically active
- active anti
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
- A61K47/6851—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a determinant of a tumour cell
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cell Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Mycology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/527,227 US5165922A (en) | 1990-05-22 | 1990-05-22 | Synergistic tumor therapy with combinations of biologically active anti-tumor antibodies and chemotherapy |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA913879B true ZA913879B (en) | 1992-03-25 |
Family
ID=24100637
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA913879A ZA913879B (en) | 1990-05-22 | 1991-05-22 | Synergistic tumor therapy with combinations of biologically active anti-tumor antibodies and chemotherapy |
Country Status (7)
Country | Link |
---|---|
US (1) | US5165922A (de) |
EP (1) | EP0575321A1 (de) |
JP (1) | JPH05508630A (de) |
CA (1) | CA2083391A1 (de) |
HU (1) | HUT63340A (de) |
WO (1) | WO1991017770A1 (de) |
ZA (1) | ZA913879B (de) |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6733752B1 (en) * | 1994-03-30 | 2004-05-11 | The Trustees Of The University Of Pennsylvania | Prevention of tumors with monoclonal antibodies against neu |
US20030180290A1 (en) * | 1995-06-07 | 2003-09-25 | Idec Pharmaceuticals Corporation | Anti-CD80 antibody having ADCC activity for ADCC mediated killing of B cell lymphoma cells alone or in combination with other therapies |
NZ332588A (en) * | 1996-05-15 | 2000-11-24 | Altarex Inc | Cancer antigens CA125 (multiple epitote) recognised by OC125, M11, B43.13, B27.1, where B43.13 is used as a binding agent to elicit host immune response as a vaccination method against cancer |
US20080220012A1 (en) * | 1996-05-15 | 2008-09-11 | Ragupathy Madiyalakan | Therapeutic Compositions that alter the immune response |
US7318921B2 (en) * | 1996-05-15 | 2008-01-15 | Altarex Medical Corp. | Therapeutic compositions that alter the immune response |
US20060159688A1 (en) * | 1996-05-15 | 2006-07-20 | Ragupathy Madiyalakan | Method for diagnosing efficacy of xenotypic antibody therapy |
US8038994B2 (en) * | 1996-05-15 | 2011-10-18 | Quest Pharmatech Inc. | Combination therapy for treating disease |
US5837231A (en) * | 1996-06-27 | 1998-11-17 | Regents Of The University Of Minnesota | GM-CSF administration for the treatment and prevention of recurrence of brain tumors |
US6410041B1 (en) * | 1998-04-28 | 2002-06-25 | Trustees Of Tufts College | Culturing cells in presence of amphipathic weak bases and/or cations and multiple drug resistance inhibitor containing reserpine |
EP1085905B1 (de) * | 1998-06-15 | 2010-09-08 | Quest Pharmatech Inc. | Immuntherapeutische zusammensetzung und verfahren zur behandlung von prostatakrebs |
CN1689646A (zh) * | 1998-08-11 | 2005-11-02 | 拜奥根Idec公司 | 包括施用抗-cd20抗体的b-细胞淋巴瘤联合疗法 |
CA2350064C (en) * | 1998-11-09 | 2012-05-08 | Idec Pharmaceuticals Corporation | Chimeric anti-cd20 antibody treatment of patients receiving bmt or pbsc transplants |
US7311924B2 (en) * | 1999-04-01 | 2007-12-25 | Hana Biosciences, Inc. | Compositions and methods for treating cancer |
DK1169021T3 (da) * | 1999-04-01 | 2010-01-11 | Hana Biosciences Inc | Sammensætninger og fremgangsmåder til behandling af lymfom |
US7244450B2 (en) * | 1999-04-01 | 2007-07-17 | Inex Pharmaceuticals Corporation | Compositions and methods for treating lymphoma |
US6723338B1 (en) * | 1999-04-01 | 2004-04-20 | Inex Pharmaceuticals Corporation | Compositions and methods for treating lymphoma |
US8557244B1 (en) | 1999-08-11 | 2013-10-15 | Biogen Idec Inc. | Treatment of aggressive non-Hodgkins lymphoma with anti-CD20 antibody |
US7740841B1 (en) * | 2000-01-28 | 2010-06-22 | Sunnybrook Health Science Center | Therapeutic method for reducing angiogenesis |
KR100881471B1 (ko) * | 2000-05-08 | 2009-02-05 | 셀덱스 쎄라퓨틱스, 인크. | 수상세포에 대한 인간 모노클로날 항체 |
US20030103971A1 (en) * | 2001-11-09 | 2003-06-05 | Kandasamy Hariharan | Immunoregulatory antibodies and uses thereof |
JP4463475B2 (ja) * | 2001-01-31 | 2010-05-19 | バイオジェン アイデック インコーポレイテッド | 腫瘍疾患の治療における免疫調節性抗体の使用 |
WO2002089772A1 (en) * | 2001-05-09 | 2002-11-14 | Inex Pharmaceuticals Corporation | Anti-angiogenic therapy using liposome-encapsulated chemotherapeutic agents |
AU2003223600A1 (en) * | 2002-04-11 | 2003-10-27 | Altarex Medical Corporation | Binding agents and their use in targeting tumor cells |
WO2006099175A2 (en) * | 2005-03-11 | 2006-09-21 | Euro-Celtique S.A. | Compositions comprising an anti-ca125 antibody and a cytotoxic compound and their use for the treatment of cancer |
US20090074757A1 (en) * | 2005-04-08 | 2009-03-19 | Enrico Pesenti | Antitumor Combination Comprising Substituted Acryloyl Distamycin Derivatives and Antibodies Inhibiting Growth Factors or Their Receptors |
EP2162152A2 (de) * | 2007-06-01 | 2010-03-17 | Biogen Idec MA, Inc. | Cripto-bindende moleküle |
CN101969970B (zh) | 2007-10-12 | 2014-10-15 | 西雅图基因公司 | 用抗体-药物偶联物联合治疗 |
JP6320756B2 (ja) * | 2010-12-06 | 2018-05-09 | キュア キャンサー ワールドワイド エルエルシー | 癌を治療するための化学および免疫療法を用いた癌細胞の代謝標的法 |
RU2655964C2 (ru) | 2012-11-20 | 2018-05-30 | Спектрум Фармасьютикалз, Инк. | Улучшенный способ получения инкапсулированного в липосомы винкристина для терапевтического применения |
TWI678213B (zh) | 2015-07-22 | 2019-12-01 | 美商史倍壯製藥公司 | 用於長春新鹼硫酸鹽脂質體注射之即可使用的調配物 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4693966A (en) * | 1983-03-11 | 1987-09-15 | Sloan-Kettering Institute For Cancer Research | Human monoclonal antibodies from lymphocytes of patients with malignant melanoma |
US4906562A (en) * | 1984-12-21 | 1990-03-06 | Oncogen | Monocolonal antibodies and antigen for human non-small cell lung carcinomas |
-
1990
- 1990-05-22 US US07/527,227 patent/US5165922A/en not_active Expired - Fee Related
-
1991
- 1991-05-17 EP EP91910573A patent/EP0575321A1/de not_active Withdrawn
- 1991-05-17 HU HU923628A patent/HUT63340A/hu unknown
- 1991-05-17 WO PCT/US1991/003483 patent/WO1991017770A1/en not_active Application Discontinuation
- 1991-05-17 JP JP91510236A patent/JPH05508630A/ja active Pending
- 1991-05-17 CA CA002083391A patent/CA2083391A1/en not_active Abandoned
- 1991-05-22 ZA ZA913879A patent/ZA913879B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
HUT63340A (en) | 1993-08-30 |
JPH05508630A (ja) | 1993-12-02 |
CA2083391A1 (en) | 1991-11-23 |
US5165922A (en) | 1992-11-24 |
WO1991017770A1 (en) | 1991-11-28 |
HU9203628D0 (en) | 1993-04-28 |
EP0575321A1 (de) | 1993-12-29 |
EP0575321A4 (de) | 1993-07-12 |
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