ZA913730B - Anti-tumor compounds - Google Patents

Anti-tumor compounds

Info

Publication number
ZA913730B
ZA913730B ZA913730A ZA913730A ZA913730B ZA 913730 B ZA913730 B ZA 913730B ZA 913730 A ZA913730 A ZA 913730A ZA 913730 A ZA913730 A ZA 913730A ZA 913730 B ZA913730 B ZA 913730B
Authority
ZA
South Africa
Prior art keywords
tumor compounds
tumor
compounds
Prior art date
Application number
ZA913730A
Other languages
English (en)
Inventor
Robert George Andrew
George Andrew Robert
Andrew John Barker
John Barker Andrew
Francis Thomas Boyle
Thomas Boyle Francis
James Michael Wardleworth
Michael Wardleworth James
Original Assignee
Ici Plc
Nat Res Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10676728&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA913730(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ici Plc, Nat Res Dev filed Critical Ici Plc
Publication of ZA913730B publication Critical patent/ZA913730B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/88—Oxygen atoms
    • C07D239/90—Oxygen atoms with acyclic radicals attached in position 2 or 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA913730A 1990-05-30 1991-05-16 Anti-tumor compounds ZA913730B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB9011989 1990-05-30

Publications (1)

Publication Number Publication Date
ZA913730B true ZA913730B (en) 1992-02-26

Family

ID=10676728

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA913730A ZA913730B (en) 1990-05-30 1991-05-16 Anti-tumor compounds

Country Status (15)

Country Link
US (1) US5280027A (fr)
EP (1) EP0459730A3 (fr)
JP (1) JPH04235173A (fr)
AU (1) AU640016B2 (fr)
CA (1) CA2042922A1 (fr)
CS (1) CS160591A3 (fr)
FI (1) FI912600A (fr)
GB (1) GB2244708B (fr)
HU (1) HUT57739A (fr)
IE (1) IE64085B1 (fr)
IL (1) IL98167A0 (fr)
NO (1) NO912071L (fr)
NZ (1) NZ238259A (fr)
PT (1) PT97799A (fr)
ZA (1) ZA913730B (fr)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9105771D0 (en) * 1991-03-19 1991-05-01 Cancer Res Inst Royal Anti-cancer compounds
GB9205320D0 (en) * 1992-03-11 1992-04-22 Ici Plc Anti-tumour compounds
GB9205907D0 (en) * 1992-03-18 1992-04-29 Cancer Res Inst Royal Anti-cancer compounds
US5430148A (en) * 1992-03-31 1995-07-04 Agouron Pharmaceuticals, Inc. Antiproliferative quinazolines
GB9220571D0 (en) * 1992-09-30 1992-11-11 Ici Plc Quinazoline derivatives
AU6709596A (en) 1995-08-22 1997-03-19 Japan Tobacco Inc. Amide compounds and use of the same
JPH09165387A (ja) * 1995-09-08 1997-06-24 Univ Princeton 非古典的抗葉酸剤
GB9904275D0 (en) * 1999-02-24 1999-04-21 Cancer Res Campaign Tech Anti-cancer compounds
US6518292B1 (en) * 1999-03-12 2003-02-11 Bristol-Myers Squibb Co. Heterocyclic aromatic compounds usefuls as growth hormone secretagogues
US6545004B1 (en) 1999-10-27 2003-04-08 Cytokinetics, Inc. Methods and compositions utilizing quinazolinones
US7230000B1 (en) 1999-10-27 2007-06-12 Cytokinetics, Incorporated Methods and compositions utilizing quinazolinones
WO2003043995A1 (fr) * 2001-11-20 2003-05-30 Cytokinetics, Inc. Procede de racemisation de quinazolinones chirales
JP2005529076A (ja) * 2002-02-15 2005-09-29 サイトキネティクス・インコーポレーテッド キナゾリノンの合成
MXPA04011074A (es) * 2002-05-09 2005-06-08 Cytokinetics Inc Compuestos de pirimidinona, composiciones y metodos.
AU2003270015A1 (en) 2002-05-09 2003-12-02 Cytokinetics, Inc. Compounds, compositions, and methods
EP1513820A4 (fr) * 2002-05-23 2006-09-13 Cytokinetics Inc Composes, compositions et procedes
AU2003236527A1 (en) * 2002-06-14 2003-12-31 Cytokinetics, Inc. Compounds, compositions, and methods
US7211580B2 (en) * 2002-07-23 2007-05-01 Cytokinetics, Incorporated Compounds, compositions, and methods
JP2005536553A (ja) * 2002-08-21 2005-12-02 サイトキネティクス・インコーポレーテッド 化合物、組成物および方法
WO2004034972A2 (fr) 2002-09-30 2004-04-29 Cytokinetics, Inc. Composes, compositions, et procedes
US20050197327A1 (en) * 2003-11-03 2005-09-08 Gustave Bergnes Compounds, compositions, and methods
US20050148593A1 (en) * 2003-11-07 2005-07-07 Gustave Bergnes Compounds, compositions, and methods
US7439254B2 (en) * 2003-12-08 2008-10-21 Cytokinetics, Inc. Compounds, compositions, and methods
KR20100024494A (ko) * 2007-06-22 2010-03-05 아르퀼 인코포레이티드 퀴나졸리논 화합물 및 이의 사용 방법
DE102010001064A1 (de) * 2009-03-18 2010-09-23 Bayer Schering Pharma Aktiengesellschaft Substituierte 2-Acetamido-5-Aryl-1,2,4-triazolone und deren Verwendung
MX2013015058A (es) 2011-06-24 2014-01-20 Amgen Inc Antagonistas de melastatina 8 de potencial receptor transitorio y su uso en tratamientos.
CN103906733A (zh) 2011-06-24 2014-07-02 安姆根有限公司 Trpm8拮抗剂及其在治疗中的用途
US8952009B2 (en) 2012-08-06 2015-02-10 Amgen Inc. Chroman derivatives as TRPM8 inhibitors
US10413583B2 (en) * 2016-11-30 2019-09-17 The University Of Chicago Synthetic substrates for enzymes that catalyze reactions of modified cysteines and related methods

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3069468D1 (en) * 1979-12-19 1984-11-22 Nat Res Dev Quinazoline derivatives, processes for their preparation, compositions containing them and their use as anti-cancer agents
GB8607683D0 (en) * 1986-03-27 1986-04-30 Ici Plc Anti-tumor agents
GB8707053D0 (en) * 1987-03-25 1987-04-29 Ici Plc Anti-tumour agents
US4857530A (en) * 1987-11-03 1989-08-15 Warner-Lambert Company Substituted quinazolinones as anticancer agents
GB8809978D0 (en) * 1988-04-27 1988-06-02 Ici Plc Anti-tumour agents
EP0365763A1 (fr) * 1988-09-30 1990-05-02 Agouron Pharmaceuticals, Inc. Composés cycliques antiproléfératifs
GB8829296D0 (en) * 1988-12-15 1989-01-25 Ici Plc Anti-tumour compounds

Also Published As

Publication number Publication date
HUT57739A (en) 1991-12-30
IL98167A0 (en) 1992-06-21
IE64085B1 (en) 1995-07-12
CS160591A3 (en) 1992-01-15
CA2042922A1 (fr) 1991-12-01
FI912600A (fi) 1991-12-01
AU7707591A (en) 1991-12-05
NO912071L (no) 1991-12-02
JPH04235173A (ja) 1992-08-24
GB2244708A (en) 1991-12-11
IE911757A1 (en) 1991-12-04
NZ238259A (en) 1993-07-27
PT97799A (pt) 1992-02-28
EP0459730A3 (en) 1993-01-20
GB2244708B (en) 1993-12-08
GB9111656D0 (en) 1991-07-24
US5280027A (en) 1994-01-18
EP0459730A2 (fr) 1991-12-04
FI912600A0 (fi) 1991-05-30
NO912071D0 (no) 1991-05-29
AU640016B2 (en) 1993-08-12

Similar Documents

Publication Publication Date Title
ZA913730B (en) Anti-tumor compounds
GB9012592D0 (en) Compounds
AP9100313A0 (en) Compounds
GB9001245D0 (en) Compounds
AP9100314A0 (en) Compounds
GB9011332D0 (en) Compounds
GB9009469D0 (en) Compounds
GB9013016D0 (en) Compounds
GB9007965D0 (en) Compounds
GB9007967D0 (en) Compounds
GB9002834D0 (en) Compounds
HU9200518D0 (en) Be-13793c anti-tumor compound
GB9007738D0 (en) Compounds
GB9009485D0 (en) Compounds
GB9005674D0 (en) Compounds
GB9005671D0 (en) Compounds
GB9004396D0 (en) Compounds
GB9008872D0 (en) Compounds
GB9009478D0 (en) Compounds
GB9009480D0 (en) Compounds
GB9004320D0 (en) Compounds
GB9000049D0 (en) Compounds
GB9003044D0 (en) Compounds
GB9001158D0 (en) Compounds
GB9013379D0 (en) Compounds