ZA913593B - Avermectin derivatives with a spacer inserted between the disaccharide and the aglycone useful as antiparasitic agents - Google Patents

Avermectin derivatives with a spacer inserted between the disaccharide and the aglycone useful as antiparasitic agents

Info

Publication number
ZA913593B
ZA913593B ZA913593A ZA913593A ZA913593B ZA 913593 B ZA913593 B ZA 913593B ZA 913593 A ZA913593 A ZA 913593A ZA 913593 A ZA913593 A ZA 913593A ZA 913593 B ZA913593 B ZA 913593B
Authority
ZA
South Africa
Prior art keywords
aglycone
disaccharide
useful
antiparasitic agents
spacer inserted
Prior art date
Application number
ZA913593A
Inventor
Timothy A Blizzard
A Blizzard Timothy
Gaye Margiatto
Margiatto Gaye
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of ZA913593B publication Critical patent/ZA913593B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Veterinary Medicine (AREA)
  • Plant Pathology (AREA)
  • Dentistry (AREA)
  • Agronomy & Crop Science (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Pest Control & Pesticides (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Saccharide Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
ZA913593A 1990-05-14 1991-05-13 Avermectin derivatives with a spacer inserted between the disaccharide and the aglycone useful as antiparasitic agents ZA913593B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/522,709 US5114930A (en) 1990-05-14 1990-05-14 Avermectin derivatives with a spacer inserted between the disaccharide and the aglycone useful as antiparasitic agents

Publications (1)

Publication Number Publication Date
ZA913593B true ZA913593B (en) 1992-02-26

Family

ID=24082002

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA913593A ZA913593B (en) 1990-05-14 1991-05-13 Avermectin derivatives with a spacer inserted between the disaccharide and the aglycone useful as antiparasitic agents

Country Status (7)

Country Link
US (1) US5114930A (en)
EP (1) EP0457517A1 (en)
JP (1) JPH04352794A (en)
AU (1) AU7701091A (en)
CA (1) CA2042418A1 (en)
NZ (1) NZ238054A (en)
ZA (1) ZA913593B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4443888A1 (en) * 1994-12-09 1996-06-13 Bayer Ag Dermally administrable formulations of parasiticides
DE19721411A1 (en) * 1997-05-22 1998-11-26 Beiersdorf Ag Use of carbohydrate compounds or carbohydrate derivatives
US8901163B2 (en) 2007-01-03 2014-12-02 Galderma S.A. Method of treating hyperesthesia, paresthesia, dolor, and pruritus caused by insect stings or noxious weeds or plants using avermectin compound
EP2629770B1 (en) 2010-10-20 2016-05-25 Galderma S.A. Ivermectin for use in treating otitis externa
CA2811924C (en) 2010-10-20 2015-06-16 Galderma S.A. Method of treating hemorrhoids using macrocyclic lactone compound

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE434277B (en) * 1976-04-19 1984-07-16 Merck & Co Inc SET TO MAKE NEW ANTIHELMINTICALLY EFFECTIVE ASSOCIATIONS BY CULTIVATING STREPTOMYCS AVERMITILIS
NZ186851A (en) * 1977-04-11 1984-12-14 Merck & Co Inc Glycosyloxy derivatives of milbemycin and parasiticidal compositions
HUT39739A (en) * 1984-12-04 1986-10-29 Ciba Geigy Ag Process for production of derivatives of 13,3-milbemycin and medical preparatives containing thereof
US4587247A (en) * 1985-02-25 1986-05-06 Merck & Co., Inc. Substituted and unsubstituted 13-(alkoxy)methoxy derivatives of the avermectin aglycones, compositions and use

Also Published As

Publication number Publication date
AU7701091A (en) 1991-11-14
NZ238054A (en) 1993-04-28
EP0457517A1 (en) 1991-11-21
CA2042418A1 (en) 1991-11-15
JPH04352794A (en) 1992-12-07
US5114930A (en) 1992-05-19

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