ZA9050B - Certain pyrrolylphenyl-substituted hydroxamic acid derivatives - Google Patents

Certain pyrrolylphenyl-substituted hydroxamic acid derivatives

Info

Publication number
ZA9050B
ZA9050B ZA9050A ZA9050A ZA9050B ZA 9050 B ZA9050 B ZA 9050B ZA 9050 A ZA9050 A ZA 9050A ZA 9050 A ZA9050 A ZA 9050A ZA 9050 B ZA9050 B ZA 9050B
Authority
ZA
South Africa
Prior art keywords
pyrrolylphenyl
certain
acid derivatives
hydroxamic acid
substituted hydroxamic
Prior art date
Application number
ZA9050A
Other languages
English (en)
Inventor
Jan William Francis Wasley
William Francis Wasley Jan
Karl Olaf Gelotte
Olaf Gelotte Karl
Harold Meckler
Meckler Harold
Original Assignee
Ciba Geigy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy filed Critical Ciba Geigy
Publication of ZA9050B publication Critical patent/ZA9050B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/325Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/325Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
    • C07D207/327Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
ZA9050A 1989-01-05 1990-01-04 Certain pyrrolylphenyl-substituted hydroxamic acid derivatives ZA9050B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US29390889A 1989-01-05 1989-01-05

Publications (1)

Publication Number Publication Date
ZA9050B true ZA9050B (en) 1990-08-29

Family

ID=23131076

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9050A ZA9050B (en) 1989-01-05 1990-01-04 Certain pyrrolylphenyl-substituted hydroxamic acid derivatives

Country Status (12)

Country Link
EP (1) EP0378991A1 (xx)
JP (1) JPH02270861A (xx)
KR (1) KR900011724A (xx)
AU (1) AU4765090A (xx)
CA (1) CA2007085A1 (xx)
DD (1) DD291551A5 (xx)
FI (1) FI900024A (xx)
HU (1) HUT53608A (xx)
IL (1) IL92915A0 (xx)
NO (1) NO900025L (xx)
PT (1) PT92762A (xx)
ZA (1) ZA9050B (xx)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5140047A (en) * 1991-05-03 1992-08-18 Smithkline Beecham Corporation Lipoxygenase inhibitors
ES2104424T3 (es) * 1993-11-26 1997-10-01 Pfizer Compuestos de isoxazolina como agentes antiinflamatorios.
AU1326795A (en) * 1994-03-09 1995-09-25 Pfizer Inc. Isoxazoline compounds as 5-lipoxygenase inhibitors
DK0970046T3 (da) * 1997-02-27 2004-04-13 Wyeth Corp N-Hydroxy-2-(alkyl-, aryl- eller heteroarylsulfanyl, -sulfinyl eller -sulfonyl)-3-substituerede alkyl- eller heteroaryl-amider som matrixmetalloproteinaseinhibitorer
US6172057B1 (en) 1997-02-27 2001-01-09 American Cyanamid Company N-Hydroxy-2-(alkyl, aryl, or heteroaryl sulfanyl, sulfinyl or sulfonyl)-3-substituted alkyl, aryl or heteroarylamides as matrix metalloproteinase inhibitors
EP1284260A4 (en) * 2000-05-22 2004-03-31 Takeda Chemical Industries Ltd TYROSINE PHOSPHATASE INHIBITORS
EP1314721A1 (en) * 2000-08-31 2003-05-28 Wakunaga Pharmaceutical Co., Ltd. Novel propenohydroxamic acid derivatives
WO2005065681A1 (en) * 2003-12-19 2005-07-21 Takeda San Diego, Inc. N- hydroxy-3-(3-(1h-imidazol-2-yl)-phenyl)-acrylamide derivatives and related compounds as histone deacetylase (hdac) inhibitors for the treatment of cancer
CN102675221A (zh) 2005-09-16 2012-09-19 武田药品工业株式会社 用于制备嘧啶二酮衍生物的方法中的中间体
TW200838536A (en) 2006-11-29 2008-10-01 Takeda Pharmaceutical Polymorphs of succinate salt of 2-[6-(3-amino-piperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-ylmethy]-4-fluor-benzonitrile and methods of use therefor

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0082109A3 (de) * 1981-10-28 1985-04-17 Ciba-Geigy Ag Substituierte 2-Hydroxy-phenylessigsäuren und Derivate davon
FR2551063A1 (fr) * 1983-08-22 1985-03-01 Inst Nat Sante Rech Med Nouveaux dimethyl-2,5 pyrroles, leur procede de preparation et leur application en therapeutique
EP0196184B1 (en) * 1985-03-16 1992-09-16 The Wellcome Foundation Limited Aryl derivatives
US4792560A (en) * 1985-04-03 1988-12-20 Rorer Pharmaceutical Corporation Quinoline hydroxamates and their use as modulators of arachidonic acid metabolic pathways
GB8531838D0 (en) * 1985-12-30 1986-02-05 Wellcome Found Aryl derivatives

Also Published As

Publication number Publication date
DD291551A5 (de) 1991-07-04
CA2007085A1 (en) 1990-07-05
PT92762A (pt) 1990-07-31
NO900025L (no) 1990-07-06
KR900011724A (ko) 1990-08-02
HU900040D0 (en) 1990-03-28
AU4765090A (en) 1990-07-12
JPH02270861A (ja) 1990-11-05
HUT53608A (en) 1990-11-28
IL92915A0 (en) 1990-09-17
FI900024A (fi) 1990-07-06
FI900024A0 (fi) 1990-01-03
NO900025D0 (no) 1990-01-04
EP0378991A1 (en) 1990-07-25

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