ZA902510B - 5-alkylquinolonecarboxylic acids - Google Patents

5-alkylquinolonecarboxylic acids

Info

Publication number
ZA902510B
ZA902510B ZA902510A ZA902510A ZA902510B ZA 902510 B ZA902510 B ZA 902510B ZA 902510 A ZA902510 A ZA 902510A ZA 902510 A ZA902510 A ZA 902510A ZA 902510 B ZA902510 B ZA 902510B
Authority
ZA
South Africa
Prior art keywords
alkylquinolonecarboxylic
acids
alkylquinolonecarboxylic acids
Prior art date
Application number
ZA902510A
Inventor
Michael Schriewer
Schriewer Michael
Klaus Grohe
Grohe Klaus
Andreas Krebs
Krebs Andreas
Uwe Petersen
Petersen Uwe
Thomas Schenke
Schenke Thomas
Ingo Haller
Haller Ingo
Karl Georg Metzger
Georg Metzger Karl
Rainer Endermann
Endermann Rainer
Hans-Joachim Zeiler
Zeiler Hans-Joachim
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of ZA902510B publication Critical patent/ZA902510B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08Bridged systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
ZA902510A 1989-04-03 1990-04-02 5-alkylquinolonecarboxylic acids ZA902510B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3910663A DE3910663A1 (en) 1989-04-03 1989-04-03 5-ALKYLCHINOLON CARBONIC ACIDS

Publications (1)

Publication Number Publication Date
ZA902510B true ZA902510B (en) 1991-01-30

Family

ID=6377683

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA902510A ZA902510B (en) 1989-04-03 1990-04-02 5-alkylquinolonecarboxylic acids

Country Status (16)

Country Link
EP (1) EP0391132A1 (en)
JP (1) JP3046035B2 (en)
KR (1) KR0156245B1 (en)
CN (1) CN1035945C (en)
AU (1) AU638005B2 (en)
CA (1) CA2013449C (en)
DD (1) DD298400A5 (en)
DE (1) DE3910663A1 (en)
FI (1) FI901615A0 (en)
HU (2) HU204811B (en)
IL (1) IL93954A0 (en)
NO (1) NO173547C (en)
NZ (1) NZ233142A (en)
PH (1) PH27364A (en)
PT (1) PT93639A (en)
ZA (1) ZA902510B (en)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4920120A (en) * 1988-01-25 1990-04-24 Warner-Lambert Company Antibacterial agents
MY105136A (en) * 1988-04-27 1994-08-30 Daiichi Seiyaku Co Optically active pyridonecarboxylic acid derivatives.
DD285601A5 (en) * 1988-07-15 1990-12-19 Bayer Ag,De PROCESS FOR PREPARING 7- (1-PYRROLIDINYL) -3-CHINOLONE AND NAPHTHYRIDONE CARBOXYLIC ACID DERIVATIVES
US5241076A (en) * 1989-04-17 1993-08-31 Bayer Aktiengesellschaft 1,4-diazatricyclo [6.3.0.0]undecanes
DE59009705D1 (en) * 1989-04-17 1995-11-02 Bayer Ag Process for the preparation of 2,7-diazabicyclo (3.3.0) octanes.
US5177210A (en) * 1989-04-17 1993-01-05 Bayer Aktiengesellschaft Preparation of 2,7-diazabicyclo(3.3.0)octanes
DE69231422T2 (en) * 1991-05-28 2001-03-29 Daiichi Pharmaceutical Co., Ltd. PYRIDONE CARBONIC ACID DERIVATIVES
DE4120646A1 (en) * 1991-06-22 1992-12-24 Bayer Ag 7-ISOINDOLINYL-CHINOLONE AND NAPHTHYRIDONE CARBONIC ACID DERIVATIVES
TW209865B (en) * 1992-01-10 1993-07-21 Bayer Ag
KR960003611B1 (en) * 1992-07-23 1996-03-20 재단법인 한국화학연구소 New diazabicyclo alkene derivatives and the preparation process thereof
DE4234078A1 (en) * 1992-10-09 1994-04-14 Bayer Ag Quinolonecarboxylic acids
DE4234330A1 (en) * 1992-10-12 1994-04-14 Bayer Ag Quinolonecarboxylic acids
CA2112165C (en) * 1992-12-25 2003-04-08 Makoto Takemura Bicyclic amine derivatives
AU4272793A (en) * 1993-04-24 1994-11-21 Korea Research Institute Of Chemical Technology Novel quinolone carboxylic acid derivatives and process for preparing the same
DE4329600A1 (en) * 1993-09-02 1995-03-09 Bayer Ag Pyrido [1,2,3-d, e] [1,3,4] benzoxadiazine derivatives
DE4339134A1 (en) * 1993-11-16 1995-05-18 Bayer Ag 1- (2-fluorocyclopropyl) quinolone and naphthyridonecarboxylic acid derivatives
DE4408212A1 (en) * 1994-03-11 1995-09-14 Bayer Ag 5-vinyl and 5-ethynyl quinolone and naphthyridone carboxylic acids
DE19546249A1 (en) * 1995-12-12 1997-06-19 Bayer Ag New crystal modification of 1-cyclopropyl-7 - ([S, S] -2,8-diazabicyclo [4,3,0] non-8-yl) -6-fluoro-1,4-dihydro-8-methoxy-4 -oxo-3-quinoline carboxylic acid hydrochloride (CDCH), process for its preparation and pharmaceutical preparations containing it
DE19633805A1 (en) * 1996-02-23 1997-08-28 Bayer Ag Optionally substituted 8-cyano-l-cyclopropyl-7- (2,8-diazabicyclo- [4.3.0] -nonan-8-yl) -6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids and their derivatives
RU2173318C2 (en) * 1996-02-23 2001-09-10 Байер Акциенгезелльшафт Fluoro-1,4-dihydro-4-oxo-3-quinoline carboxylic acids, their derivatives and pharmaceutical composition eliciting anti-bacterial activity
DE19652239A1 (en) 1996-12-16 1998-06-18 Bayer Ag Use of 7- (2-oxa-5,8-diazabicyclo [4.3.0] non-8-yl) -quinolone and naphthyridonecarboxylic acid derivatives for the therapy of Helicobacter pylori infections and the associated gastroduodenal diseases
DE19854357A1 (en) * 1998-11-25 2000-05-31 Bayer Ag Semi-hydrochloride of 8-cyano-1-cyclopropyl-7- (1S, 6S-2,8-diazabicyclo / 4.3.0 / -nonan-8-yl) -6-fluoro-1,4-dihydro-4-oxo -3-quinoline carboxylic acid
DE19854356A1 (en) * 1998-11-25 2000-05-31 Bayer Ag Crystal modification A of 8-cyan-1-cyclopropyl-7- (1S, 6S-2,8-diazabicyclo- / 4.3.0 / nonan-8-yl) -6-fluoro-1,4-dihydro-4-oxo 3-quinoline carboxylic acid
DE19854355A1 (en) * 1998-11-25 2000-05-31 Bayer Ag Crystal modification B of 8-cyan-1-cyclopropyl-7- (1S, 6S-2,8-diazabicyclo- / 4.3.O / nonan-8-yl) -6-fluoro-1,4-dihydro-4-oxo 3-quinoline carboxylic acid
CA2498291C (en) 2002-09-10 2009-04-07 Pfizer Products Inc. Diazabicyclic compounds useful in the treatment of cns and other disorders
AU2004272414B2 (en) 2003-09-10 2009-05-28 Kyorin Pharmaceutical Co., Ltd. 7-(4-substituted 3- cyclopropylaminomethyl-1- pyrrolidinyl) quinolonecarboxylic acid derivative
WO2008143343A1 (en) 2007-05-24 2008-11-27 Kyorin Pharmaceutical Co., Ltd. Mutilin derivative having heterocyclic aromatic ring carboxylic acid structure in substituent at 14-position
CN101718743B (en) * 2009-11-30 2013-03-20 宁波大学 Method for preparing mixed conductor dense diffusion barrier-type oxygen sensor

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3522405A1 (en) * 1985-06-22 1987-01-02 Bayer Ag 1,8-BRIDGED 4-CHINOLON-3-CARBONIC ACIDS, METHOD FOR THE PRODUCTION THEREOF AND THE MEDICINAL PRODUCTS CONTAINING THE SAME AND THE USE THEREOF FOR THE PRODUCTION OF MEDICINAL PRODUCTS
DE3543513A1 (en) * 1985-12-10 1987-06-11 Bayer Ag ENANTIOMER-PURE 1,8-BRIDGED 4-CHINOLON-3-CARBONIC ACIDS, METHOD FOR THE PRODUCTION THEREOF AND THE MEDICINAL PRODUCTS CONTAINING THEM AND THEIR USE FOR THE PRODUCTION OF MEDICINAL PRODUCTS
DE3601567A1 (en) * 1986-01-21 1987-07-23 Bayer Ag 7- (AZABICYCLOALKYL) -CHINOLONCARBONIC ACID AND -NAPHTHYRIDON-CARBONIC ACID DERIVATIVES
DE3702393A1 (en) * 1987-01-28 1988-08-11 Bayer Ag 8-CYANO-1-CYCLOPROPYL-1,4-DIHYDRO-4-OXO- 3-CHINOLINE CARBONIC ACIDS, METHOD FOR THEIR PRODUCTION AND ANTIBACTERIAL AGENTS CONTAINING THEM
US5591744A (en) * 1987-04-16 1997-01-07 Otsuka Pharmaceutical Company, Limited Benzoheterocyclic compounds
US4920120A (en) * 1988-01-25 1990-04-24 Warner-Lambert Company Antibacterial agents

Also Published As

Publication number Publication date
NO901274D0 (en) 1990-03-20
JP3046035B2 (en) 2000-05-29
IL93954A0 (en) 1990-12-23
NO173547C (en) 1993-12-29
PH27364A (en) 1993-06-21
EP0391132A1 (en) 1990-10-10
KR0156245B1 (en) 1998-11-16
HU204811B (en) 1992-02-28
DE3910663A1 (en) 1990-10-04
CN1035945C (en) 1997-09-24
JPH02289583A (en) 1990-11-29
CN1046162A (en) 1990-10-17
DD298400A5 (en) 1992-02-20
AU5231790A (en) 1990-10-04
FI901615A0 (en) 1990-03-30
CA2013449A1 (en) 1990-10-03
KR900016186A (en) 1990-11-12
HUT56563A (en) 1991-09-30
HUT58056A (en) 1992-01-28
CA2013449C (en) 2001-01-02
AU638005B2 (en) 1993-06-17
NO173547B (en) 1993-09-20
HU902055D0 (en) 1990-08-28
PT93639A (en) 1990-11-20
NO901274L (en) 1990-10-04
HU912263D0 (en) 1991-12-30
NZ233142A (en) 1992-09-25

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