AU5231790A - 5-alkylquinolonecarboxylic acids - Google Patents

5-alkylquinolonecarboxylic acids

Info

Publication number
AU5231790A
AU5231790A AU52317/90A AU5231790A AU5231790A AU 5231790 A AU5231790 A AU 5231790A AU 52317/90 A AU52317/90 A AU 52317/90A AU 5231790 A AU5231790 A AU 5231790A AU 5231790 A AU5231790 A AU 5231790A
Authority
AU
Australia
Prior art keywords
alkylquinolonecarboxylic
acids
alkylquinolonecarboxylic acids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU52317/90A
Other versions
AU638005B2 (en
Inventor
Rainer Endermann
Klaus Grohe
Ingo Haller
Andreas Krebs
Karl Georg Metzger
Uwe Petersen
Thomas Schenke
Michael Schriewer
Hans-Joachim Zeiler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Publication of AU5231790A publication Critical patent/AU5231790A/en
Application granted granted Critical
Publication of AU638005B2 publication Critical patent/AU638005B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems
AU52317/90A 1989-04-03 1990-03-28 5-alkylquinolonecarboxylic acids Ceased AU638005B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3910663A DE3910663A1 (en) 1989-04-03 1989-04-03 5-ALKYLCHINOLON CARBONIC ACIDS
DE3910663 1989-04-03

Publications (2)

Publication Number Publication Date
AU5231790A true AU5231790A (en) 1990-10-04
AU638005B2 AU638005B2 (en) 1993-06-17

Family

ID=6377683

Family Applications (1)

Application Number Title Priority Date Filing Date
AU52317/90A Ceased AU638005B2 (en) 1989-04-03 1990-03-28 5-alkylquinolonecarboxylic acids

Country Status (16)

Country Link
EP (1) EP0391132A1 (en)
JP (1) JP3046035B2 (en)
KR (1) KR0156245B1 (en)
CN (1) CN1035945C (en)
AU (1) AU638005B2 (en)
CA (1) CA2013449C (en)
DD (1) DD298400A5 (en)
DE (1) DE3910663A1 (en)
FI (1) FI901615A0 (en)
HU (2) HU204811B (en)
IL (1) IL93954A0 (en)
NO (1) NO173547C (en)
NZ (1) NZ233142A (en)
PH (1) PH27364A (en)
PT (1) PT93639A (en)
ZA (1) ZA902510B (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU624118B2 (en) * 1988-01-25 1992-06-04 Warner-Lambert Company Antibacterial agents
AU625414B2 (en) * 1988-04-27 1992-07-09 Daiichi Pharmaceutical Co., Ltd. Optically active pyridonecarboxylic acid derivatives
AU668286B2 (en) * 1988-07-15 1996-04-26 Bayer Schering Pharma Aktiengesellschaft Diazabicyclo(4.3.0)nonane and (3.3.0)octane heterocycles
US5696132A (en) * 1991-05-28 1997-12-09 Daiichi Pharmaceutical Co., Ltd. Pyridonecarboxylic acid derivatives

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5177210A (en) * 1989-04-17 1993-01-05 Bayer Aktiengesellschaft Preparation of 2,7-diazabicyclo(3.3.0)octanes
ATE128466T1 (en) * 1989-04-17 1995-10-15 Bayer Ag METHOD FOR PRODUCING 2,7-DIAZABICYCLO(3.3.0)OCTANE.
US5241076A (en) * 1989-04-17 1993-08-31 Bayer Aktiengesellschaft 1,4-diazatricyclo [6.3.0.0]undecanes
DE4120646A1 (en) * 1991-06-22 1992-12-24 Bayer Ag 7-ISOINDOLINYL-CHINOLONE AND NAPHTHYRIDONE CARBONIC ACID DERIVATIVES
TW209865B (en) * 1992-01-10 1993-07-21 Bayer Ag
KR960003611B1 (en) * 1992-07-23 1996-03-20 재단법인 한국화학연구소 New diazabicyclo alkene derivatives and the preparation process thereof
DE4234078A1 (en) * 1992-10-09 1994-04-14 Bayer Ag Quinolonecarboxylic acids
DE4234330A1 (en) * 1992-10-12 1994-04-14 Bayer Ag Quinolonecarboxylic acids
JP3268098B2 (en) * 1992-12-25 2002-03-25 第一製薬株式会社 Bicyclic cyclic amine derivative
AU4272793A (en) * 1993-04-24 1994-11-21 Korea Research Institute Of Chemical Technology Novel quinolone carboxylic acid derivatives and process for preparing the same
DE4329600A1 (en) * 1993-09-02 1995-03-09 Bayer Ag Pyrido [1,2,3-d, e] [1,3,4] benzoxadiazine derivatives
DE4339134A1 (en) * 1993-11-16 1995-05-18 Bayer Ag 1- (2-fluorocyclopropyl) quinolone and naphthyridonecarboxylic acid derivatives
DE4408212A1 (en) * 1994-03-11 1995-09-14 Bayer Ag 5-vinyl and 5-ethynyl quinolone and naphthyridone carboxylic acids
DE19546249A1 (en) * 1995-12-12 1997-06-19 Bayer Ag New crystal modification of 1-cyclopropyl-7 - ([S, S] -2,8-diazabicyclo [4,3,0] non-8-yl) -6-fluoro-1,4-dihydro-8-methoxy-4 -oxo-3-quinoline carboxylic acid hydrochloride (CDCH), process for its preparation and pharmaceutical preparations containing it
DE59708771D1 (en) * 1996-02-23 2003-01-02 Bayer Ag SUBSTITUTED 8-CYAN-1-CYCLOPROPYL-7- (2,8-DIAZABICYCLO- 4.3.0] -NONAN-8-YL) -6-FLUOR-1,4-DIHYDRO-4-OXO-3-CHINOLINE CARBONIC ACIDS AND YOUR DERIVATIVES
DE19633805A1 (en) * 1996-02-23 1997-08-28 Bayer Ag Optionally substituted 8-cyano-l-cyclopropyl-7- (2,8-diazabicyclo- [4.3.0] -nonan-8-yl) -6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids and their derivatives
DE19652239A1 (en) * 1996-12-16 1998-06-18 Bayer Ag Use of 7- (2-oxa-5,8-diazabicyclo [4.3.0] non-8-yl) -quinolone and naphthyridonecarboxylic acid derivatives for the therapy of Helicobacter pylori infections and the associated gastroduodenal diseases
DE19854355A1 (en) * 1998-11-25 2000-05-31 Bayer Ag Crystal modification B of 8-cyan-1-cyclopropyl-7- (1S, 6S-2,8-diazabicyclo- / 4.3.O / nonan-8-yl) -6-fluoro-1,4-dihydro-4-oxo 3-quinoline carboxylic acid
DE19854357A1 (en) * 1998-11-25 2000-05-31 Bayer Ag Semi-hydrochloride of 8-cyano-1-cyclopropyl-7- (1S, 6S-2,8-diazabicyclo / 4.3.0 / -nonan-8-yl) -6-fluoro-1,4-dihydro-4-oxo -3-quinoline carboxylic acid
DE19854356A1 (en) * 1998-11-25 2000-05-31 Bayer Ag Crystal modification A of 8-cyan-1-cyclopropyl-7- (1S, 6S-2,8-diazabicyclo- / 4.3.0 / nonan-8-yl) -6-fluoro-1,4-dihydro-4-oxo 3-quinoline carboxylic acid
BR0314201A (en) 2002-09-10 2005-07-12 Pfizer Prod Inc Diazabicyclic Compounds Useful in the Treatment of CNS Diseases and Other Disorders
CA2536429C (en) 2003-09-10 2012-02-14 Kyorin Pharmaceutical Co., Ltd. 7-(4-substituted-3-cyclopropylaminomethyl-1-pyrrolidinyl) quinolonecarboxylic acid derivative
US8222407B2 (en) 2007-05-24 2012-07-17 Kyorin Pharmaceutical Co., Ltd. Mutilin derivative having heterocyclic aromatic ring carboxylic acid structure in substituent at 14-position
CN101718743B (en) * 2009-11-30 2013-03-20 宁波大学 Method for preparing mixed conductor dense diffusion barrier-type oxygen sensor

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3522405A1 (en) * 1985-06-22 1987-01-02 Bayer Ag 1,8-BRIDGED 4-CHINOLON-3-CARBONIC ACIDS, METHOD FOR THE PRODUCTION THEREOF AND THE MEDICINAL PRODUCTS CONTAINING THE SAME AND THE USE THEREOF FOR THE PRODUCTION OF MEDICINAL PRODUCTS
DE3543513A1 (en) * 1985-12-10 1987-06-11 Bayer Ag ENANTIOMER-PURE 1,8-BRIDGED 4-CHINOLON-3-CARBONIC ACIDS, METHOD FOR THE PRODUCTION THEREOF AND THE MEDICINAL PRODUCTS CONTAINING THEM AND THEIR USE FOR THE PRODUCTION OF MEDICINAL PRODUCTS
DE3601567A1 (en) * 1986-01-21 1987-07-23 Bayer Ag 7- (AZABICYCLOALKYL) -CHINOLONCARBONIC ACID AND -NAPHTHYRIDON-CARBONIC ACID DERIVATIVES
DE3702393A1 (en) * 1987-01-28 1988-08-11 Bayer Ag 8-CYANO-1-CYCLOPROPYL-1,4-DIHYDRO-4-OXO- 3-CHINOLINE CARBONIC ACIDS, METHOD FOR THEIR PRODUCTION AND ANTIBACTERIAL AGENTS CONTAINING THEM
US5563138A (en) * 1987-04-16 1996-10-08 Otsuka Pharmaceutical Company, Limited Benzoheterocyclic compounds
US4920120A (en) * 1988-01-25 1990-04-24 Warner-Lambert Company Antibacterial agents

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU624118B2 (en) * 1988-01-25 1992-06-04 Warner-Lambert Company Antibacterial agents
AU625414B2 (en) * 1988-04-27 1992-07-09 Daiichi Pharmaceutical Co., Ltd. Optically active pyridonecarboxylic acid derivatives
AU668286B2 (en) * 1988-07-15 1996-04-26 Bayer Schering Pharma Aktiengesellschaft Diazabicyclo(4.3.0)nonane and (3.3.0)octane heterocycles
US5696132A (en) * 1991-05-28 1997-12-09 Daiichi Pharmaceutical Co., Ltd. Pyridonecarboxylic acid derivatives

Also Published As

Publication number Publication date
FI901615A0 (en) 1990-03-30
AU638005B2 (en) 1993-06-17
PH27364A (en) 1993-06-21
HU204811B (en) 1992-02-28
NZ233142A (en) 1992-09-25
ZA902510B (en) 1991-01-30
JPH02289583A (en) 1990-11-29
DD298400A5 (en) 1992-02-20
IL93954A0 (en) 1990-12-23
CA2013449A1 (en) 1990-10-03
PT93639A (en) 1990-11-20
NO901274L (en) 1990-10-04
EP0391132A1 (en) 1990-10-10
CA2013449C (en) 2001-01-02
CN1046162A (en) 1990-10-17
CN1035945C (en) 1997-09-24
NO173547B (en) 1993-09-20
HU912263D0 (en) 1991-12-30
KR0156245B1 (en) 1998-11-16
HUT56563A (en) 1991-09-30
HU902055D0 (en) 1990-08-28
NO901274D0 (en) 1990-03-20
KR900016186A (en) 1990-11-12
JP3046035B2 (en) 2000-05-29
NO173547C (en) 1993-12-29
HUT58056A (en) 1992-01-28
DE3910663A1 (en) 1990-10-04

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Legal Events

Date Code Title Description
MK14 Patent ceased section 143(a) (annual fees not paid) or expired