ZA897854B - Prodrugs of antiinflammatory 3-acyl-2-oxindole-1-carboxamines - Google Patents
Prodrugs of antiinflammatory 3-acyl-2-oxindole-1-carboxaminesInfo
- Publication number
- ZA897854B ZA897854B ZA897854A ZA897854A ZA897854B ZA 897854 B ZA897854 B ZA 897854B ZA 897854 A ZA897854 A ZA 897854A ZA 897854 A ZA897854 A ZA 897854A ZA 897854 B ZA897854 B ZA 897854B
- Authority
- ZA
- South Africa
- Prior art keywords
- carboxamines
- oxindole
- antiinflammatory
- prodrugs
- acyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/34—Oxygen atoms in position 2
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US36588888A | 1988-10-18 | 1988-10-18 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA897854B true ZA897854B (en) | 1991-05-29 |
Family
ID=23440804
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA897854A ZA897854B (en) | 1988-10-18 | 1989-10-17 | Prodrugs of antiinflammatory 3-acyl-2-oxindole-1-carboxamines |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0365194B1 (de) |
DE (1) | DE68923673T2 (de) |
ES (1) | ES2075055T3 (de) |
GR (1) | GR3017565T3 (de) |
ZA (1) | ZA897854B (de) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5118703A (en) * | 1988-10-18 | 1992-06-02 | Pfizer Inc. | Prodrugs of antiinflammatory 3-acyl-2-oxindole-1-carboxamides |
US5270331A (en) * | 1993-01-26 | 1993-12-14 | Pfizer, Inc. | Prodrugs of antiinflammatory 3-acyl-2-oxindole-1-carboxamides |
DE69305999T2 (de) * | 1993-02-09 | 1997-03-06 | Pfizer Inc., New York, N.Y. | Oxindol 1-[n-(alkoxycarbonyl)]carboxamide und 1-[n-carboxamido]carboxamide als antiinflammatorische wirkstoffe |
JP2008280248A (ja) * | 2005-11-02 | 2008-11-20 | Eisai R & D Management Co Ltd | アルツハイマー型痴呆症治療薬塩酸ドネペジルのプロドラッグ |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5323551B2 (de) * | 1972-01-10 | 1978-07-15 | ||
US4556672A (en) * | 1984-03-19 | 1985-12-03 | Pfizer Inc. | 3-Substituted 2-oxindole-1-carboxamides as analgesic and anti-inflammatory agents |
UA25898A1 (uk) * | 1987-02-02 | 1999-02-26 | Пфайзер Інк. | Спосіб одержаhhя кристалічhої hатрієвої солі 5-хлор-3-(2-теhоїл)-2-оксііhдол-1-карбоксаміду |
US5047554A (en) * | 1989-04-18 | 1991-09-10 | Pfizer Inc. | 3-substituted-2-oxindole derivatives |
-
1989
- 1989-10-09 ES ES89310319T patent/ES2075055T3/es not_active Expired - Lifetime
- 1989-10-09 DE DE68923673T patent/DE68923673T2/de not_active Expired - Fee Related
- 1989-10-09 EP EP89310319A patent/EP0365194B1/de not_active Expired - Lifetime
- 1989-10-17 ZA ZA897854A patent/ZA897854B/xx unknown
-
1995
- 1995-09-28 GR GR950402678T patent/GR3017565T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
EP0365194B1 (de) | 1995-08-02 |
EP0365194A2 (de) | 1990-04-25 |
DE68923673T2 (de) | 1996-01-18 |
GR3017565T3 (en) | 1995-12-31 |
DE68923673D1 (de) | 1995-09-07 |
EP0365194A3 (de) | 1991-07-03 |
ES2075055T3 (es) | 1995-10-01 |
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