ZA891078B - Novel aspartate transcarbamylase inhibitors - Google Patents

Novel aspartate transcarbamylase inhibitors

Info

Publication number
ZA891078B
ZA891078B ZA891078A ZA891078A ZA891078B ZA 891078 B ZA891078 B ZA 891078B ZA 891078 A ZA891078 A ZA 891078A ZA 891078 A ZA891078 A ZA 891078A ZA 891078 B ZA891078 B ZA 891078B
Authority
ZA
South Africa
Prior art keywords
aspartate transcarbamylase
inhibitors
novel
novel aspartate
transcarbamylase inhibitors
Prior art date
Application number
ZA891078A
Other languages
English (en)
Inventor
Serge Halazy
Halazy Serge
Charles Danzin
Danzin Charles
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of ZA891078B publication Critical patent/ZA891078B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40—Esters thereof
    • C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4006—Esters of acyclic acids which can have further substituents on alkyl
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3808—Acyclic saturated acids which can have further substituents on alkyl

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA891078A 1988-02-16 1989-02-10 Novel aspartate transcarbamylase inhibitors ZA891078B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP88400348A EP0328834A1 (en) 1988-02-16 1988-02-16 Novel aspartate transcarbamylase inhibitors

Publications (1)

Publication Number Publication Date
ZA891078B true ZA891078B (en) 1989-10-25

Family

ID=8200350

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA891078A ZA891078B (en) 1988-02-16 1989-02-10 Novel aspartate transcarbamylase inhibitors

Country Status (12)

Country Link
EP (2) EP0328834A1 (xx)
JP (1) JPH02149589A (xx)
CN (1) CN1036207A (xx)
AU (1) AU609942B2 (xx)
DK (1) DK69489A (xx)
FI (1) FI890695A (xx)
HU (1) HUT49142A (xx)
IL (1) IL89287A (xx)
NO (1) NO890644L (xx)
NZ (1) NZ227978A (xx)
PT (1) PT89718B (xx)
ZA (1) ZA891078B (xx)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0465297B1 (en) * 1990-07-04 1996-01-31 Merrell Dow Pharmaceuticals Inc. 9-Purinyl phosphonic acid derivatives
US5095007A (en) * 1990-10-24 1992-03-10 Ahluwalia Gurpreet S Alteration of rate and character of hair growth
GB9200826D0 (en) * 1992-01-15 1992-03-11 Celltech Ltd Peptidyl derivatives
US11104639B2 (en) 2016-09-14 2021-08-31 Daikin Industries, Ltd. Branched fluorine-containing compound

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3425701A1 (de) * 1984-07-12 1986-01-16 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von chlorierten phosphorylmethylcarbonyl-derivaten und neue zwischenprodukte zu ihrer herstellung
FR2590259B1 (fr) * 1985-11-20 1989-05-12 Roussel Uclaf Procede de preparation de derives fluores de l'acide phosphonique, et produits obtenus par la mise en oeuvre de ce procede
FR2596393B1 (fr) * 1986-04-01 1988-06-03 Sanofi Sa Derives de l'acide hydroxy-3 dihydroxyoxophosphorio-4 butanoique, leur procede de preparation, leur application comme medicament et les compositions les renfermant

Also Published As

Publication number Publication date
DK69489D0 (da) 1989-02-15
NO890644D0 (no) 1989-02-15
EP0331550A1 (en) 1989-09-06
HUT49142A (en) 1989-08-28
FI890695A0 (fi) 1989-02-14
CN1036207A (zh) 1989-10-11
DK69489A (da) 1989-08-17
IL89287A0 (en) 1989-09-10
AU609942B2 (en) 1991-05-09
FI890695A (fi) 1989-08-17
JPH02149589A (ja) 1990-06-08
AU2990489A (en) 1989-08-17
PT89718B (pt) 1994-03-31
IL89287A (en) 1993-02-21
NZ227978A (en) 1990-10-26
NO890644L (no) 1989-08-17
PT89718A (pt) 1989-10-04
EP0328834A1 (en) 1989-08-23

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