IL89287A - Halogenated phosphonic acid derivatives and aspartate transcarbamylase inhibitors and compositions containing them for tumor therapy - Google Patents
Halogenated phosphonic acid derivatives and aspartate transcarbamylase inhibitors and compositions containing them for tumor therapyInfo
- Publication number
- IL89287A IL89287A IL89287A IL8928789A IL89287A IL 89287 A IL89287 A IL 89287A IL 89287 A IL89287 A IL 89287A IL 8928789 A IL8928789 A IL 8928789A IL 89287 A IL89287 A IL 89287A
- Authority
- IL
- Israel
- Prior art keywords
- compositions containing
- acid derivatives
- phosphonic acid
- tumor therapy
- aspartate transcarbamylase
- Prior art date
Links
- 102000030907 Aspartate Carbamoyltransferase Human genes 0.000 title 1
- 108091000126 Dihydroorotase Chemical class 0.000 title 1
- 206010028980 Neoplasm Diseases 0.000 title 1
- 229940042400 direct acting antivirals phosphonic acid derivative Drugs 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 150000003007 phosphonic acid derivatives Chemical class 0.000 title 1
- 238000002560 therapeutic procedure Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/40—Esters thereof
- C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4006—Esters of acyclic acids which can have further substituents on alkyl
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
- C07F9/3808—Acyclic saturated acids which can have further substituents on alkyl
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP88400348A EP0328834A1 (en) | 1988-02-16 | 1988-02-16 | Novel aspartate transcarbamylase inhibitors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL89287A0 IL89287A0 (en) | 1989-09-10 |
| IL89287A true IL89287A (en) | 1993-02-21 |
Family
ID=8200350
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL89287A IL89287A (en) | 1988-02-16 | 1989-02-14 | Halogenated phosphonic acid derivatives and aspartate transcarbamylase inhibitors and compositions containing them for tumor therapy |
Country Status (12)
| Country | Link |
|---|---|
| EP (2) | EP0328834A1 (xx) |
| JP (1) | JPH02149589A (xx) |
| CN (1) | CN1036207A (xx) |
| AU (1) | AU609942B2 (xx) |
| DK (1) | DK69489A (xx) |
| FI (1) | FI890695A (xx) |
| HU (1) | HUT49142A (xx) |
| IL (1) | IL89287A (xx) |
| NO (1) | NO890644L (xx) |
| NZ (1) | NZ227978A (xx) |
| PT (1) | PT89718B (xx) |
| ZA (1) | ZA891078B (xx) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2085446T3 (es) * | 1990-07-04 | 1996-06-01 | Merrell Pharma Inc | Derivados de acido 9-purinil fosfonico. |
| US5095007A (en) * | 1990-10-24 | 1992-03-10 | Ahluwalia Gurpreet S | Alteration of rate and character of hair growth |
| GB9200826D0 (en) * | 1992-01-15 | 1992-03-11 | Celltech Ltd | Peptidyl derivatives |
| JP7037069B2 (ja) * | 2016-09-14 | 2022-03-16 | ダイキン工業株式会社 | 分枝含フッ素化合物 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3425701A1 (de) * | 1984-07-12 | 1986-01-16 | Bayer Ag, 5090 Leverkusen | Verfahren zur herstellung von chlorierten phosphorylmethylcarbonyl-derivaten und neue zwischenprodukte zu ihrer herstellung |
| FR2590259B1 (fr) * | 1985-11-20 | 1989-05-12 | Roussel Uclaf | Procede de preparation de derives fluores de l'acide phosphonique, et produits obtenus par la mise en oeuvre de ce procede |
| FR2596393B1 (fr) * | 1986-04-01 | 1988-06-03 | Sanofi Sa | Derives de l'acide hydroxy-3 dihydroxyoxophosphorio-4 butanoique, leur procede de preparation, leur application comme medicament et les compositions les renfermant |
-
1988
- 1988-02-16 EP EP88400348A patent/EP0328834A1/en not_active Withdrawn
-
1989
- 1989-02-10 ZA ZA891078A patent/ZA891078B/xx unknown
- 1989-02-13 AU AU29904/89A patent/AU609942B2/en not_active Ceased
- 1989-02-14 FI FI890695A patent/FI890695A/fi not_active Application Discontinuation
- 1989-02-14 IL IL89287A patent/IL89287A/xx not_active IP Right Cessation
- 1989-02-14 NZ NZ227978A patent/NZ227978A/en unknown
- 1989-02-15 HU HU89767A patent/HUT49142A/hu unknown
- 1989-02-15 NO NO89890644A patent/NO890644L/no unknown
- 1989-02-15 CN CN89100817A patent/CN1036207A/zh active Pending
- 1989-02-15 EP EP89400420A patent/EP0331550A1/en not_active Ceased
- 1989-02-15 DK DK069489A patent/DK69489A/da not_active Application Discontinuation
- 1989-02-15 PT PT89718A patent/PT89718B/pt not_active IP Right Cessation
- 1989-02-16 JP JP1035199A patent/JPH02149589A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| FI890695A (fi) | 1989-08-17 |
| CN1036207A (zh) | 1989-10-11 |
| HUT49142A (en) | 1989-08-28 |
| EP0331550A1 (en) | 1989-09-06 |
| NO890644L (no) | 1989-08-17 |
| NO890644D0 (no) | 1989-02-15 |
| AU609942B2 (en) | 1991-05-09 |
| FI890695A0 (fi) | 1989-02-14 |
| JPH02149589A (ja) | 1990-06-08 |
| NZ227978A (en) | 1990-10-26 |
| AU2990489A (en) | 1989-08-17 |
| ZA891078B (en) | 1989-10-25 |
| EP0328834A1 (en) | 1989-08-23 |
| PT89718B (pt) | 1994-03-31 |
| PT89718A (pt) | 1989-10-04 |
| DK69489D0 (da) | 1989-02-15 |
| IL89287A0 (en) | 1989-09-10 |
| DK69489A (da) | 1989-08-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM9K | Patent not in force due to non-payment of renewal fees | ||
| HC | Change of name of proprietor(s) |
Owner name: AVENTIS INC. Free format text: FORMER NAME:MERRELL PHARMACEUTICALS INC. |