ZA888396B - Process for the production of biodegradable microcapsules of water-soluble peptides and proteins,and microcapsules obtained by this process - Google Patents

Process for the production of biodegradable microcapsules of water-soluble peptides and proteins,and microcapsules obtained by this process

Info

Publication number
ZA888396B
ZA888396B ZA888396A ZA888396A ZA888396B ZA 888396 B ZA888396 B ZA 888396B ZA 888396 A ZA888396 A ZA 888396A ZA 888396 A ZA888396 A ZA 888396A ZA 888396 B ZA888396 B ZA 888396B
Authority
ZA
South Africa
Prior art keywords
microcapsules
proteins
production
water
soluble peptides
Prior art date
Application number
ZA888396A
Inventor
Rainer Schmiedel
Schmiedel Rainer
Juergen Kurt Sandow
Kurt Sandow Juergen
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of ZA888396B publication Critical patent/ZA888396B/en

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/06—Making microcapsules or microballoons by phase separation
    • B01J13/12—Making microcapsules or microballoons by phase separation removing solvent from the wall-forming material solution
    • B01J13/125—Making microcapsules or microballoons by phase separation removing solvent from the wall-forming material solution by evaporation of the solvent
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
ZA888396A 1987-11-11 1988-11-09 Process for the production of biodegradable microcapsules of water-soluble peptides and proteins,and microcapsules obtained by this process ZA888396B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19873738228 DE3738228A1 (en) 1987-11-11 1987-11-11 METHOD FOR PRODUCING BIODEGRADABLE MICRO-CAPSULES OF WATER-SOLUBLE PEPTIDES AND PROTEINS AND MICRO-CAPSULES OBTAINED BY THIS PROCESS

Publications (1)

Publication Number Publication Date
ZA888396B true ZA888396B (en) 1989-07-26

Family

ID=6340243

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA888396A ZA888396B (en) 1987-11-11 1988-11-09 Process for the production of biodegradable microcapsules of water-soluble peptides and proteins,and microcapsules obtained by this process

Country Status (11)

Country Link
EP (1) EP0315875A1 (en)
JP (1) JPH01155942A (en)
KR (1) KR890007789A (en)
AU (1) AU2503788A (en)
DE (1) DE3738228A1 (en)
DK (1) DK627488A (en)
FI (1) FI885152A (en)
IL (1) IL88370A0 (en)
NO (1) NO885013L (en)
PT (1) PT88974A (en)
ZA (1) ZA888396B (en)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3916020C2 (en) * 1989-05-17 1994-06-01 Burkhard Dr Wichert Retarding microparticles made from biodegradable polyesters; Process for their preparation without the use of toxic solvents and pharmaceutical preparations containing these microparticles
HU221294B1 (en) * 1989-07-07 2002-09-28 Novartis Ag Process for producing retarde compositions containing the active ingredient in a polymeric carrier
EP0423484B1 (en) * 1989-10-16 1993-11-03 PCD-Polymere Gesellschaft m.b.H. Tablet with sustained release
DE4041563A1 (en) * 1990-12-22 1992-06-25 Sanol Arznei Schwarz Gmbh METHOD FOR PRODUCING ACTIVE MICROPARTICLES FROM HYDROLYTICALLY DEGRADABLE POLYMERS
YU48420B (en) * 1991-03-25 1998-07-10 Hoechst Aktiengesellschaft PROCEDURE FOR OBTAINING BIOLOGICAL DEGRADABLE MICROPARTICLES WITH LONG TERM ACTION
DE69220317T2 (en) * 1991-10-01 1997-10-16 Takeda Chemical Industries Ltd Microparticle summary for extended release and manufacture of the same
JP2651320B2 (en) * 1992-07-16 1997-09-10 田辺製薬株式会社 Method for producing sustained-release microsphere preparation
AU4198793A (en) * 1992-07-24 1994-01-27 Takeda Chemical Industries Ltd. Microparticle preparation and production thereof
FR2693905B1 (en) * 1992-07-27 1994-09-02 Rhone Merieux Process for the preparation of microspheres for the sustained release of the hormone LHRH and its analogs, microspheres and formulations obtained.
HU221308B1 (en) * 1992-10-26 2002-09-28 Sanol Arznei Schwarz Gmbh Process for producing microcapsules
US6290991B1 (en) 1994-12-02 2001-09-18 Quandrant Holdings Cambridge Limited Solid dose delivery vehicle and methods of making same
US6117455A (en) * 1994-09-30 2000-09-12 Takeda Chemical Industries, Ltd. Sustained-release microcapsule of amorphous water-soluble pharmaceutical active agent
DE19545257A1 (en) 1995-11-24 1997-06-19 Schering Ag Process for the production of morphologically uniform microcapsules and microcapsules produced by this process
EP1343480B2 (en) 2000-12-21 2016-02-17 Alrise Biosystems GmbH Induced phase transition method for the production of microparticles containing hydrophobic active agents
US20040146561A1 (en) 2001-05-23 2004-07-29 Naoki Sakurai Compositions for promoting healing of bone fracture
WO2002094320A1 (en) 2001-05-23 2002-11-28 Tanabe Seiyaku Co., Ltd. Therapeutic compositions for repairing chondropathy
KR20030024103A (en) * 2001-09-17 2003-03-26 육순홍 Preparation of nanosphere composed of biodegradable polymers using phase transition for drug delivery
CN105963257B (en) * 2016-04-26 2021-01-22 广州帝奇医药技术有限公司 Preparation method of sustained-release particles
CN105963258B (en) * 2016-04-26 2021-01-22 广州帝奇医药技术有限公司 Preparation method of sustained-release particles
CN108525617B (en) * 2018-04-26 2020-01-14 中国农业科学院植物保护研究所 Preparation method of fenoxanil microcapsule for reducing toxicity of fenoxanil on zebra fish

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3773919A (en) * 1969-10-23 1973-11-20 Du Pont Polylactide-drug mixtures
PH19942A (en) * 1980-11-18 1986-08-14 Sintex Inc Microencapsulation of water soluble polypeptides
DE3428372A1 (en) * 1984-08-01 1986-02-13 Hoechst Ag, 6230 Frankfurt CONTROLLED RELEASE REGULAR PEPTIDES MICROCAPSULES, PRODUCTION METHOD AND INJECTION PREPARATIONS
EP0190833B1 (en) * 1985-02-07 1991-03-27 Takeda Chemical Industries, Ltd. Method for producing microcapsule
US4832686A (en) * 1986-06-24 1989-05-23 Anderson Mark E Method for administering interleukin-2

Also Published As

Publication number Publication date
FI885152A (en) 1989-05-12
NO885013D0 (en) 1988-11-10
NO885013L (en) 1989-05-12
DK627488A (en) 1989-05-12
EP0315875A1 (en) 1989-05-17
FI885152A0 (en) 1988-11-09
JPH01155942A (en) 1989-06-19
AU2503788A (en) 1989-05-25
DK627488D0 (en) 1988-11-10
DE3738228A1 (en) 1989-05-24
KR890007789A (en) 1989-07-05
IL88370A0 (en) 1989-06-30
PT88974A (en) 1989-11-30

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