ZA884315B - Combined use of an antigestagen and a progesterone synthesis inhibitor of the trilostane and epostane type - Google Patents

Combined use of an antigestagen and a progesterone synthesis inhibitor of the trilostane and epostane type

Info

Publication number
ZA884315B
ZA884315B ZA884315A ZA884315A ZA884315B ZA 884315 B ZA884315 B ZA 884315B ZA 884315 A ZA884315 A ZA 884315A ZA 884315 A ZA884315 A ZA 884315A ZA 884315 B ZA884315 B ZA 884315B
Authority
ZA
South Africa
Prior art keywords
antigestagen
trilostane
synthesis inhibitor
combined use
progesterone synthesis
Prior art date
Application number
ZA884315A
Inventor
Walter Elger
Elger Walter
Sybille Beier
Beier Sybille
Beate Kosub
Kosub Beate
Marianne Faehnrich
Faehnrich Marianne
Krzysztof Chwalisz
Chwalisz Krzysztof
Syed Hamiduddin Hasan
Hamiduddin Hasan Syed
Gordon Oliver Potts
Oliver Potts Gordon
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of ZA884315B publication Critical patent/ZA884315B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/04—Drugs for genital or sexual disorders; Contraceptives for inducing labour or abortion; Uterotonics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Epidemiology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Hematology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Oncology (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The medicine contains a progesterone synthesis inhibitor (ProH) of the trilostane or epostane type and an antigestagen (AG) and is used for inducing labour at term in humans and animals and for terminating normal or pathological pregnancy. The combination according to the invention is also suitable for treating hormone-dependent tumours, endometriosis and dysmenorrhoea.
ZA884315A 1987-06-16 1988-06-16 Combined use of an antigestagen and a progesterone synthesis inhibitor of the trilostane and epostane type ZA884315B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19873720420 DE3720420A1 (en) 1987-06-16 1987-06-16 PROGESTERONE SYNTHESIS INHIBITOR AND ANTI-STAGE TO BEGINNING BIRTH OR FOR PREGNANCY

Publications (1)

Publication Number Publication Date
ZA884315B true ZA884315B (en) 1989-06-28

Family

ID=6329981

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA884315A ZA884315B (en) 1987-06-16 1988-06-16 Combined use of an antigestagen and a progesterone synthesis inhibitor of the trilostane and epostane type

Country Status (12)

Country Link
EP (1) EP0296097B1 (en)
JP (1) JP2716461B2 (en)
AT (1) ATE94391T1 (en)
AU (1) AU611160B2 (en)
CA (1) CA1318251C (en)
DE (2) DE3720420A1 (en)
DK (1) DK327288A (en)
ES (1) ES2059556T3 (en)
IE (1) IE63453B1 (en)
IL (1) IL86731A (en)
PH (1) PH25728A (en)
ZA (1) ZA884315B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3522753B2 (en) * 1992-09-25 2004-04-26 バーンズ，クライブ Prevention of deposition of pollutants in beer lines
GB2345851B (en) * 2000-01-18 2004-05-26 Gavin Paul Vinson A combination of trilostane or keto-trilostane and an anti-oestrogen for the treatment of an oestrogen-dependent cancer or tumour

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4062954A (en) * 1976-12-27 1977-12-13 Sterling Drug Inc. Process for using a steroid compound
IL68222A (en) * 1983-03-24 1987-02-27 Yeda Res & Dev Contraceptive compositions comprising a progesterone antagonist and a blocker of progesterone activity

Also Published As

Publication number Publication date
IE63453B1 (en) 1995-04-19
IL86731A0 (en) 1988-11-30
JP2716461B2 (en) 1998-02-18
EP0296097B1 (en) 1993-09-15
DE3884067D1 (en) 1993-10-21
IL86731A (en) 1992-11-15
DE3720420A1 (en) 1988-12-29
ES2059556T3 (en) 1994-11-16
JPS63316725A (en) 1988-12-26
DK327288A (en) 1988-12-17
DK327288D0 (en) 1988-06-15
ATE94391T1 (en) 1993-10-15
EP0296097A2 (en) 1988-12-21
EP0296097A3 (en) 1990-04-04
AU1775088A (en) 1988-12-22
PH25728A (en) 1991-10-18
CA1318251C (en) 1993-05-25
IE881804L (en) 1988-12-16
AU611160B2 (en) 1991-06-06

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