AU1775088A - Combined use of an antigestagen and a progesterone synthesis inhibitor of the trilostane and epostane type - Google Patents

Combined use of an antigestagen and a progesterone synthesis inhibitor of the trilostane and epostane type

Info

Publication number
AU1775088A
AU1775088A AU17750/88A AU1775088A AU1775088A AU 1775088 A AU1775088 A AU 1775088A AU 17750/88 A AU17750/88 A AU 17750/88A AU 1775088 A AU1775088 A AU 1775088A AU 1775088 A AU1775088 A AU 1775088A
Authority
AU
Australia
Prior art keywords
antigestagen
trilostane
synthesis inhibitor
combined use
progesterone synthesis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU17750/88A
Other versions
AU611160B2 (en
Inventor
Sybille Dr. Beier
Krysztof Dr. Chwalisz
Walter Dr. Elger
Marianne Fahnrich
Syed Hamiduddin Dr. Hasan
Beate Kosub
Gordon Oliver Dr. Potts
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering AG filed Critical Schering AG
Publication of AU1775088A publication Critical patent/AU1775088A/en
Application granted granted Critical
Publication of AU611160B2 publication Critical patent/AU611160B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/04—Drugs for genital or sexual disorders; Contraceptives for inducing labour or abortion; Uterotonics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Epidemiology (AREA)
  • Reproductive Health (AREA)
  • Oncology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Gynecology & Obstetrics (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The medicine contains a progesterone synthesis inhibitor (ProH) of the trilostane or epostane type and an antigestagen (AG) and is used for inducing labour at term in humans and animals and for terminating normal or pathological pregnancy. The combination according to the invention is also suitable for treating hormone-dependent tumours, endometriosis and dysmenorrhoea.
AU17750/88A 1987-06-16 1988-06-16 Combined use of an antigestagen and a progesterone synthesis inhibitor of the trilostane and epostane type Ceased AU611160B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19873720420 DE3720420A1 (en) 1987-06-16 1987-06-16 PROGESTERONE SYNTHESIS INHIBITOR AND ANTI-STAGE TO BEGINNING BIRTH OR FOR PREGNANCY
DE3720420 1987-06-16

Publications (2)

Publication Number Publication Date
AU1775088A true AU1775088A (en) 1988-12-22
AU611160B2 AU611160B2 (en) 1991-06-06

Family

ID=6329981

Family Applications (1)

Application Number Title Priority Date Filing Date
AU17750/88A Ceased AU611160B2 (en) 1987-06-16 1988-06-16 Combined use of an antigestagen and a progesterone synthesis inhibitor of the trilostane and epostane type

Country Status (12)

Country Link
EP (1) EP0296097B1 (en)
JP (1) JP2716461B2 (en)
AT (1) ATE94391T1 (en)
AU (1) AU611160B2 (en)
CA (1) CA1318251C (en)
DE (2) DE3720420A1 (en)
DK (1) DK327288A (en)
ES (1) ES2059556T3 (en)
IE (1) IE63453B1 (en)
IL (1) IL86731A (en)
PH (1) PH25728A (en)
ZA (1) ZA884315B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0667834T3 (en) * 1992-09-25 2000-10-30 Clive Barnes Prevention of formation of contaminant coatings in beer pipes
GB2345851B (en) * 2000-01-18 2004-05-26 Gavin Paul Vinson A combination of trilostane or keto-trilostane and an anti-oestrogen for the treatment of an oestrogen-dependent cancer or tumour

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4062954A (en) * 1976-12-27 1977-12-13 Sterling Drug Inc. Process for using a steroid compound
IL68222A (en) * 1983-03-24 1987-02-27 Yeda Res & Dev Contraceptive compositions comprising a progesterone antagonist and a blocker of progesterone activity

Also Published As

Publication number Publication date
EP0296097A3 (en) 1990-04-04
JP2716461B2 (en) 1998-02-18
DE3720420A1 (en) 1988-12-29
IL86731A (en) 1992-11-15
PH25728A (en) 1991-10-18
JPS63316725A (en) 1988-12-26
DE3884067D1 (en) 1993-10-21
ZA884315B (en) 1989-06-28
AU611160B2 (en) 1991-06-06
EP0296097A2 (en) 1988-12-21
CA1318251C (en) 1993-05-25
ES2059556T3 (en) 1994-11-16
EP0296097B1 (en) 1993-09-15
DK327288A (en) 1988-12-17
ATE94391T1 (en) 1993-10-15
IE63453B1 (en) 1995-04-19
IE881804L (en) 1988-12-16
DK327288D0 (en) 1988-06-15
IL86731A0 (en) 1988-11-30

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Legal Events

Date Code Title Description
MK14 Patent ceased section 143(a) (annual fees not paid) or expired