ZA882100B - Dopamine-beta-hydroxylase inhibitors - Google Patents

Dopamine-beta-hydroxylase inhibitors

Info

Publication number
ZA882100B
ZA882100B ZA882100A ZA882100A ZA882100B ZA 882100 B ZA882100 B ZA 882100B ZA 882100 A ZA882100 A ZA 882100A ZA 882100 A ZA882100 A ZA 882100A ZA 882100 B ZA882100 B ZA 882100B
Authority
ZA
South Africa
Prior art keywords
dopamine
beta
hydroxylase inhibitors
hydroxylase
inhibitors
Prior art date
Application number
ZA882100A
Other languages
English (en)
Inventor
Joseph Alan Finkelstein
Alan Finkelstein Joseph
Lawrence Ivan Kruse
Ivan Kruse Lawrence
Thomas Brent Leonard
Brent Leonard Thomas
Original Assignee
Smithkline Beckman Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beckman Corp filed Critical Smithkline Beckman Corp
Publication of ZA882100B publication Critical patent/ZA882100B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/90Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA882100A 1987-03-24 1988-03-24 Dopamine-beta-hydroxylase inhibitors ZA882100B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/029,512 US4762850A (en) 1987-03-24 1987-03-24 Dopamine-beta-hydroxylase inhibitors

Publications (1)

Publication Number Publication Date
ZA882100B true ZA882100B (en) 1989-10-25

Family

ID=21849416

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA882100A ZA882100B (en) 1987-03-24 1988-03-24 Dopamine-beta-hydroxylase inhibitors

Country Status (7)

Country Link
US (1) US4762850A (xx)
EP (1) EP0284375A1 (xx)
JP (1) JPS63255268A (xx)
AU (1) AU1370688A (xx)
DK (1) DK163088A (xx)
PT (1) PT87079B (xx)
ZA (1) ZA882100B (xx)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4882348A (en) * 1987-12-29 1989-11-21 Smithkline Beckman Corporation 2-(aminoalkylthio)imidazoles as dopamine-β-hydroxylase inhibitors
CA1338238C (en) * 1988-01-07 1996-04-09 David John Carini Angiotensin ii receptor blocking imidazoles and combinations thereof with diuretics and nsaids
KR950009860B1 (ko) 1989-06-30 1995-08-29 이. 아이. 듀퐁 드 네모아 앤드 캄파니 융합된 환 아릴 치환된 이미다졸과 약제학적으로 허용되는 이의 염, 이들의 제조방법 및 이들을 함유하는 약제학적 조성물
CA2032289A1 (en) * 1989-12-29 1991-06-30 Joseph A. Finkelstein Substituted 5-(alkyl) carboxamide imidazoles
DE4200954A1 (de) * 1991-04-26 1992-10-29 Bayer Ag Heterocyclisch substituierte phenylessigsaeurederivate
EP3971178A1 (en) 2012-03-07 2022-03-23 The McLean Hospital Corporation Aminoquinoline derivatives and uses thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3217094A1 (de) * 1982-05-07 1983-11-10 Hoechst Ag, 6230 Frankfurt 1-substituierte imidazol-5-carbonsaeurederivate, ihre herstellung sowie ihre verwendung als biozide
US4532331A (en) * 1983-04-12 1985-07-30 Smithkline Beckman Corporation 1-Benzyl-2-aminomethyl imidazole derivatives
PT78388B (en) * 1983-04-12 1986-09-15 Smithkline Beckman Corp Dopamine-beta-hydroxylase inhibitors
US4743613A (en) * 1986-04-08 1988-05-10 Smithkline Beckman Corporation Ester prodrugs of dopamine-β-hydroxylase, inhibitors, composition containing them, and method of using them to inhibit dopamine-β-hydroxylase activity

Also Published As

Publication number Publication date
EP0284375A1 (en) 1988-09-28
JPS63255268A (ja) 1988-10-21
DK163088A (da) 1988-09-25
AU1370688A (en) 1988-09-22
DK163088D0 (da) 1988-03-24
PT87079B (pt) 1992-07-31
PT87079A (pt) 1988-04-01
US4762850A (en) 1988-08-09

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