ZA881555B - Tendamistat derivatives - Google Patents

Tendamistat derivatives

Info

Publication number
ZA881555B
ZA881555B ZA881555A ZA881555A ZA881555B ZA 881555 B ZA881555 B ZA 881555B ZA 881555 A ZA881555 A ZA 881555A ZA 881555 A ZA881555 A ZA 881555A ZA 881555 B ZA881555 B ZA 881555B
Authority
ZA
South Africa
Prior art keywords
tendamistat
derivatives
proteins
tendamistate
enzymatically
Prior art date
Application number
ZA881555A
Inventor
Koller Klaus-Peter
Engels Joachim
Neeb Martin
Original Assignee
Hoechst Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Aktiengesellschaft filed Critical Hoechst Aktiengesellschaft
Publication of ZA881555B publication Critical patent/ZA881555B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/36—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Actinomyces; from Streptomyces (G)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Transplantation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)

Abstract

By variation of the tendamistate gene, modified alpha -amylase inhibitors having changed properties, or proteins or fusion proteins reacting reversibly with the corresponding receptors are obtained, from which the desired protein contained therein is released chemically or enzymatically.
ZA881555A 1987-03-06 1988-03-04 Tendamistat derivatives ZA881555B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19873707150 DE3707150A1 (en) 1987-03-06 1987-03-06 TENDAMISTAT DERIVATIVES

Publications (1)

Publication Number Publication Date
ZA881555B true ZA881555B (en) 1988-08-25

Family

ID=6322379

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA881555A ZA881555B (en) 1987-03-06 1988-03-04 Tendamistat derivatives

Country Status (11)

Country Link
EP (1) EP0281090B1 (en)
JP (1) JPS63230095A (en)
KR (1) KR880011200A (en)
AT (1) ATE89603T1 (en)
AU (1) AU611417B2 (en)
DE (2) DE3707150A1 (en)
DK (1) DK118888A (en)
FI (1) FI880986A (en)
NO (1) NO880952L (en)
PT (1) PT86891B (en)
ZA (1) ZA881555B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3714866A1 (en) * 1987-05-05 1988-11-24 Hoechst Ag METHOD FOR THE PRODUCTION OF FOREIGN PROTEINS IN STREPTOMYCETES
DE4012818A1 (en) * 1990-04-21 1991-10-24 Hoechst Ag METHOD FOR THE PRODUCTION OF FOREIGN PROTEINS IN STREPTOMYCETES
US5426036A (en) * 1987-05-05 1995-06-20 Hoechst Aktiengesellschaft Processes for the preparation of foreign proteins in streptomycetes
DE3837271A1 (en) * 1988-11-03 1990-05-10 Hoechst Ag PROCESS FOR THE SELECTIVE CLEARANCE OF FUSION PROTEINS
DE58909556D1 (en) * 1988-11-03 1996-02-15 Hoechst Ag Process for the production of an insulin precursor in streptomycetes

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3331860A1 (en) * 1983-09-03 1985-03-21 Hoechst Ag, 6230 Frankfurt Process for the preparation of tendamistat
DE3418274A1 (en) * 1984-05-17 1985-11-21 Hoechst Ag, 6230 Frankfurt SIGNAL PEPTIDE FOR THE EXCRETION OF PEPTIDES IN STREPTOMYCETS
US4910297A (en) * 1987-06-29 1990-03-20 Abi Biotechnology Inc. Alpha-amylase inhibitor

Also Published As

Publication number Publication date
EP0281090A2 (en) 1988-09-07
FI880986A (en) 1988-09-07
EP0281090B1 (en) 1993-05-19
ATE89603T1 (en) 1993-06-15
JPS63230095A (en) 1988-09-26
AU611417B2 (en) 1991-06-13
EP0281090A3 (en) 1990-05-02
PT86891B (en) 1992-05-29
DK118888A (en) 1988-09-07
PT86891A (en) 1988-04-01
NO880952L (en) 1988-09-07
DE3881080D1 (en) 1993-06-24
DE3707150A1 (en) 1988-09-15
NO880952D0 (en) 1988-03-03
DK118888D0 (en) 1988-03-04
AU1264388A (en) 1988-09-08
FI880986A0 (en) 1988-03-03
KR880011200A (en) 1988-10-27

Similar Documents

Publication Publication Date Title
AU2324488A (en) Modular assembly of antibody genes, antibodies prepared thereby and use
AU573523B2 (en) Functional human urokinase proteins
AU554290B2 (en) N, 3-disubstituted 2-oxindole-1-carboxamides
AU1482488A (en) Leader sequences for the production of recombinant proteins
DE3853265D1 (en) Reduction of the logical path length using Boolean minimization.
DE3856433D1 (en) Triazolin (thi) on intermediates for the production of herbicides
AU5233686A (en) Dna sequence encoding a hirudin-like protein and process for preparing such protein
AU1527188A (en) Factor viii binding domain of von willebrand factor
DE3853446D1 (en) Fibronectin binding protein and its production.
ZA881555B (en) Tendamistat derivatives
WO2000026370A3 (en) Adenine nucleotide translocator (ant) fusion proteins and uses thereof
ATE285474T1 (en) HAEMOPHILUS ADHESION PROTEINS
AP8800109A0 (en) "Heterocyclic insecticides".
ATE63543T1 (en) 2-OXINDOLE INTERMEDIATE.
EP0316748A3 (en) Process for the selective cleavage of fusion proteins
DE59809481D1 (en) Process for the preparation of aminocyanacetamide
IT8921657A0 (en) PROCEDURE FOR THE PRODUCTION OF SOFT LEAD-FREE LEATHER.
DE3888216D1 (en) Method for the production of amino hydrocarbon substituted ketoximosilanes.
DE3886222D1 (en) USE OF 4- [1-OXOALKYL] -2,5-OXAZOLIDE INDIONS FOR THE SELECTIVE STEREOSPECIFIC FORMATION OF BIOLOGICALLY ACTIVE BETA LACTAMS.
ES8704072A1 (en) Refinement of raw proteines.
IL83118A (en) N-acylated-n)- alkylcarbothioic acid hydrazides
DE3884430D1 (en) METHOD OF PRODUCING CHLORINE OLEFINS.
HUT47769A (en) Base driver circuitry of transistor controlled by push-pull signals, with optical isolating
FI883339A (en) Process for the preparation of -2 ', 3'-dideoxyinosine by enzymatic deamination