FI883339A - Process for the preparation of -2 ', 3'-dideoxyinosine by enzymatic deamination - Google Patents

Process for the preparation of -2 ', 3'-dideoxyinosine by enzymatic deamination Download PDF

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Publication number
FI883339A
FI883339A FI883339A FI883339A FI883339A FI 883339 A FI883339 A FI 883339A FI 883339 A FI883339 A FI 883339A FI 883339 A FI883339 A FI 883339A FI 883339 A FI883339 A FI 883339A
Authority
FI
Finland
Prior art keywords
dideoxyinosine
preparation
enzymatic deamination
deamination
enzymatic
Prior art date
Application number
FI883339A
Other languages
Finnish (fi)
Swedish (sv)
Other versions
FI883339A0 (en
FI92602C (en
FI92602B (en
Inventor
Vittorio Farina
Daniel A Benigni
Paul R Brodfuehrer
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of FI883339A0 publication Critical patent/FI883339A0/en
Publication of FI883339A publication Critical patent/FI883339A/en
Application granted granted Critical
Publication of FI92602B publication Critical patent/FI92602B/en
Publication of FI92602C publication Critical patent/FI92602C/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/30—Nucleotides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/38—Nucleosides
    • C12P19/40—Nucleosides having a condensed ring system containing a six-membered ring having two nitrogen atoms in the same ring, e.g. purine nucleosides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
FI883339A 1987-07-17 1988-07-13 Process for the preparation of -2 ', 3'-dideoxyinosine by enzymatic deamination FI92602C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7484487A 1987-07-17 1987-07-17
US7484487 1987-07-17

Publications (4)

Publication Number Publication Date
FI883339A0 FI883339A0 (en) 1988-07-13
FI883339A true FI883339A (en) 1989-01-18
FI92602B FI92602B (en) 1994-08-31
FI92602C FI92602C (en) 1994-12-12

Family

ID=22122017

Family Applications (1)

Application Number Title Priority Date Filing Date
FI883339A FI92602C (en) 1987-07-17 1988-07-13 Process for the preparation of -2 ', 3'-dideoxyinosine by enzymatic deamination

Country Status (8)

Country Link
KR (1) KR930005870B1 (en)
AT (1) AT395977B (en)
CA (1) CA1335187C (en)
ES (1) ES2007532A6 (en)
FI (1) FI92602C (en)
GR (1) GR1000483B (en)
LU (1) LU87280A1 (en)
PT (1) PT88017B (en)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1314875C (en) * 1985-05-15 1993-03-23 George Walter Koszalka Therapeutic nucleosides
IL85778A0 (en) * 1987-03-20 1988-09-30 Bristol Myers Co Production of 2',3'-dideoxynucleosides and certain such novel compounds

Also Published As

Publication number Publication date
LU87280A1 (en) 1989-03-08
AT395977B (en) 1993-04-26
GR880100455A (en) 1989-04-12
PT88017A (en) 1989-06-30
CA1335187C (en) 1995-04-11
FI883339A0 (en) 1988-07-13
FI92602C (en) 1994-12-12
FI92602B (en) 1994-08-31
PT88017B (en) 1995-03-01
ATA173088A (en) 1992-09-15
GR1000483B (en) 1992-07-30
ES2007532A6 (en) 1989-06-16
KR930005870B1 (en) 1993-06-25
KR900001858A (en) 1990-02-27

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Legal Events

Date Code Title Description
BB Publication of examined application
FG Patent granted

Owner name: BRISTOL-MYERS SQUIBB COMPANY