ZA881426B - Crystalline quinapril and a process for producing the same - Google Patents
Crystalline quinapril and a process for producing the sameInfo
- Publication number
- ZA881426B ZA881426B ZA881426A ZA881426A ZA881426B ZA 881426 B ZA881426 B ZA 881426B ZA 881426 A ZA881426 A ZA 881426A ZA 881426 A ZA881426 A ZA 881426A ZA 881426 B ZA881426 B ZA 881426B
- Authority
- ZA
- South Africa
- Prior art keywords
- quinapril
- producing
- same
- crystalline quinapril
- novel
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Peptides Or Proteins (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Steroid Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/032,209 US4761479A (en) | 1987-03-30 | 1987-03-30 | Crystalline quinapril and a process for producing the same |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA881426B true ZA881426B (en) | 1989-10-25 |
Family
ID=21863696
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA881426A ZA881426B (en) | 1987-03-30 | 1988-02-29 | Crystalline quinapril and a process for producing the same |
Country Status (13)
Country | Link |
---|---|
US (1) | US4761479A (fr) |
EP (1) | EP0285992B1 (fr) |
JP (1) | JP2659990B2 (fr) |
KR (1) | KR960007087B1 (fr) |
AT (1) | ATE62229T1 (fr) |
AU (1) | AU605555B2 (fr) |
CA (1) | CA1291999C (fr) |
DE (1) | DE3862227D1 (fr) |
ES (1) | ES2021778B3 (fr) |
GR (1) | GR3001736T3 (fr) |
NZ (1) | NZ223671A (fr) |
PH (1) | PH24986A (fr) |
ZA (1) | ZA881426B (fr) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2122941B1 (es) * | 1997-05-29 | 1999-07-01 | Esteve Quimica Sa | Procedimiento para la obtencion de quinapril clorhidrato y solvatos utiles para el aislamiento y purificacion de quinapril clorhidrato. |
NZ333206A (en) * | 1998-12-08 | 2000-07-28 | Bernard Charles Sherman | Solid pharmaceutical compositions comprising a stable magnesium salt of quinapril that acts as a ACE (Angiotensin Converting Enzyme) inhibitor |
US20030225124A1 (en) * | 1999-08-31 | 2003-12-04 | Spiridon Spireas | Stable formulations of ACE inhibitors, and methods for preparation thereof |
ATE360616T1 (de) * | 2002-12-16 | 2007-05-15 | Lupin Ltd | Kristalline form von quinapril hydrochlorid und verfahren zu dessen herstellung |
CL2004000541A1 (es) * | 2003-03-31 | 2005-02-04 | Warner Lambert Co | Procedimiento de preparacion de clorhidrato de quinapril por reaccion entre una 2,5-dioxo-oxazolidina y un ester terbutilico de una tetrahidro isoquinolina, util como principio activo para tratar la hipertension y la insuficiencia cardiaca congestiva |
WO2007069268A2 (fr) * | 2005-10-14 | 2007-06-21 | Sun Pharmaceutical Industries Limited | Procédé pour la préparation de dérivés de l'acide 1,2,3,4-tétrahydroisoquinoline-3-carboxylique pratiquement purs |
WO2009113081A1 (fr) * | 2008-03-10 | 2009-09-17 | Lupin Limited | Sel de tris(hydroxyméthyl)aminométhane de quinapril et de ramipril |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4294832A (en) * | 1979-04-28 | 1981-10-13 | Tanabe Seiyaku Co., Ltd. | Tetrahydroisoquinoline compounds and a pharmaceutical composition thereof |
US4344949A (en) * | 1980-10-03 | 1982-08-17 | Warner-Lambert Company | Substituted acyl derivatives of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids |
-
1987
- 1987-03-30 US US07/032,209 patent/US4761479A/en not_active Expired - Lifetime
-
1988
- 1988-02-26 NZ NZ223671A patent/NZ223671A/xx unknown
- 1988-02-29 ZA ZA881426A patent/ZA881426B/xx unknown
- 1988-02-29 AU AU12383/88A patent/AU605555B2/en not_active Ceased
- 1988-03-04 CA CA000560594A patent/CA1291999C/fr not_active Expired - Lifetime
- 1988-03-25 PH PH36687A patent/PH24986A/en unknown
- 1988-03-29 EP EP88105131A patent/EP0285992B1/fr not_active Expired - Lifetime
- 1988-03-29 DE DE8888105131T patent/DE3862227D1/de not_active Expired - Lifetime
- 1988-03-29 JP JP63073492A patent/JP2659990B2/ja not_active Expired - Lifetime
- 1988-03-29 ES ES88105131T patent/ES2021778B3/es not_active Expired - Lifetime
- 1988-03-29 AT AT88105131T patent/ATE62229T1/de not_active IP Right Cessation
- 1988-03-30 KR KR1019880003494A patent/KR960007087B1/ko not_active IP Right Cessation
-
1991
- 1991-04-04 GR GR91400309T patent/GR3001736T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
ES2021778B3 (es) | 1991-11-16 |
DE3862227D1 (de) | 1991-05-08 |
NZ223671A (en) | 1990-10-26 |
JPS63258459A (ja) | 1988-10-25 |
PH24986A (en) | 1990-12-26 |
EP0285992A1 (fr) | 1988-10-12 |
US4761479A (en) | 1988-08-02 |
KR880011110A (ko) | 1988-10-26 |
KR960007087B1 (ko) | 1996-05-27 |
CA1291999C (fr) | 1991-11-12 |
GR3001736T3 (en) | 1992-11-23 |
JP2659990B2 (ja) | 1997-09-30 |
AU1238388A (en) | 1988-09-29 |
ATE62229T1 (de) | 1991-04-15 |
EP0285992B1 (fr) | 1991-04-03 |
AU605555B2 (en) | 1991-01-17 |
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