ZA881426B - Crystalline quinapril and a process for producing the same - Google Patents

Crystalline quinapril and a process for producing the same

Info

Publication number
ZA881426B
ZA881426B ZA881426A ZA881426A ZA881426B ZA 881426 B ZA881426 B ZA 881426B ZA 881426 A ZA881426 A ZA 881426A ZA 881426 A ZA881426 A ZA 881426A ZA 881426 B ZA881426 B ZA 881426B
Authority
ZA
South Africa
Prior art keywords
quinapril
producing
same
crystalline quinapril
novel
Prior art date
Application number
ZA881426A
Other languages
English (en)
Inventor
Om Prakash Goel
Prakash Goel Om
Uldis Krolls
Krolls Uldis
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of ZA881426B publication Critical patent/ZA881426B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Peptides Or Proteins (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA881426A 1987-03-30 1988-02-29 Crystalline quinapril and a process for producing the same ZA881426B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/032,209 US4761479A (en) 1987-03-30 1987-03-30 Crystalline quinapril and a process for producing the same

Publications (1)

Publication Number Publication Date
ZA881426B true ZA881426B (en) 1989-10-25

Family

ID=21863696

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA881426A ZA881426B (en) 1987-03-30 1988-02-29 Crystalline quinapril and a process for producing the same

Country Status (13)

Country Link
US (1) US4761479A (fr)
EP (1) EP0285992B1 (fr)
JP (1) JP2659990B2 (fr)
KR (1) KR960007087B1 (fr)
AT (1) ATE62229T1 (fr)
AU (1) AU605555B2 (fr)
CA (1) CA1291999C (fr)
DE (1) DE3862227D1 (fr)
ES (1) ES2021778B3 (fr)
GR (1) GR3001736T3 (fr)
NZ (1) NZ223671A (fr)
PH (1) PH24986A (fr)
ZA (1) ZA881426B (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2122941B1 (es) * 1997-05-29 1999-07-01 Esteve Quimica Sa Procedimiento para la obtencion de quinapril clorhidrato y solvatos utiles para el aislamiento y purificacion de quinapril clorhidrato.
NZ333206A (en) * 1998-12-08 2000-07-28 Bernard Charles Sherman Solid pharmaceutical compositions comprising a stable magnesium salt of quinapril that acts as a ACE (Angiotensin Converting Enzyme) inhibitor
US20030225124A1 (en) * 1999-08-31 2003-12-04 Spiridon Spireas Stable formulations of ACE inhibitors, and methods for preparation thereof
ATE360616T1 (de) * 2002-12-16 2007-05-15 Lupin Ltd Kristalline form von quinapril hydrochlorid und verfahren zu dessen herstellung
CL2004000541A1 (es) * 2003-03-31 2005-02-04 Warner Lambert Co Procedimiento de preparacion de clorhidrato de quinapril por reaccion entre una 2,5-dioxo-oxazolidina y un ester terbutilico de una tetrahidro isoquinolina, util como principio activo para tratar la hipertension y la insuficiencia cardiaca congestiva
WO2007069268A2 (fr) * 2005-10-14 2007-06-21 Sun Pharmaceutical Industries Limited Procédé pour la préparation de dérivés de l'acide 1,2,3,4-tétrahydroisoquinoline-3-carboxylique pratiquement purs
WO2009113081A1 (fr) * 2008-03-10 2009-09-17 Lupin Limited Sel de tris(hydroxyméthyl)aminométhane de quinapril et de ramipril

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4294832A (en) * 1979-04-28 1981-10-13 Tanabe Seiyaku Co., Ltd. Tetrahydroisoquinoline compounds and a pharmaceutical composition thereof
US4344949A (en) * 1980-10-03 1982-08-17 Warner-Lambert Company Substituted acyl derivatives of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids

Also Published As

Publication number Publication date
ES2021778B3 (es) 1991-11-16
DE3862227D1 (de) 1991-05-08
NZ223671A (en) 1990-10-26
JPS63258459A (ja) 1988-10-25
PH24986A (en) 1990-12-26
EP0285992A1 (fr) 1988-10-12
US4761479A (en) 1988-08-02
KR880011110A (ko) 1988-10-26
KR960007087B1 (ko) 1996-05-27
CA1291999C (fr) 1991-11-12
GR3001736T3 (en) 1992-11-23
JP2659990B2 (ja) 1997-09-30
AU1238388A (en) 1988-09-29
ATE62229T1 (de) 1991-04-15
EP0285992B1 (fr) 1991-04-03
AU605555B2 (en) 1991-01-17

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