ZA873771B - A composition for transdermal therapeutic systems of loop diuretics and a process for its preparation - Google Patents

A composition for transdermal therapeutic systems of loop diuretics and a process for its preparation

Info

Publication number
ZA873771B
ZA873771B ZA873771A ZA873771A ZA873771B ZA 873771 B ZA873771 B ZA 873771B ZA 873771 A ZA873771 A ZA 873771A ZA 873771 A ZA873771 A ZA 873771A ZA 873771 B ZA873771 B ZA 873771B
Authority
ZA
South Africa
Prior art keywords
carbon atoms
composition
transdermal therapeutic
moiety
therapeutic systems
Prior art date
Application number
ZA873771A
Inventor
Hropot Max
Petri Walter
Reul Bernhard
Original Assignee
Hoechst Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Aktiengesellschaft filed Critical Hoechst Aktiengesellschaft
Publication of ZA873771B publication Critical patent/ZA873771B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics

Abstract

There is described a composition for transdermal therapeutic systems which contain, as active substance, furosemid, piretanid or lemidosul or a physiologically acceptable salt of these loop diuretics in a base consisting of a fatty acid alkanolamide or a mixture of fatty acid alkanolamides having 8-18 carbon atoms in the fatty acid moiety and 2 to 6 carbon atoms and 1 to 3 hydroxyl groups in the alkanolamide moiety and, if appropriate, a carboxylic ester or a mixture of carboxylic esters having in each case 1-22 carbon atoms in the carboxylic acid moiety and 1-22 carbon atoms in the alcohol moiety.
ZA873771A 1986-05-27 1987-05-26 A composition for transdermal therapeutic systems of loop diuretics and a process for its preparation ZA873771B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19863617824 DE3617824A1 (en) 1986-05-27 1986-05-27 COMPOSITION FOR TRANSDERMAL THERAPEUTIC SYSTEMS OF LOOP DIRECTIVES

Publications (1)

Publication Number Publication Date
ZA873771B true ZA873771B (en) 1987-11-20

Family

ID=6301739

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA873771A ZA873771B (en) 1986-05-27 1987-05-26 A composition for transdermal therapeutic systems of loop diuretics and a process for its preparation

Country Status (13)

Country Link
EP (1) EP0247507B1 (en)
JP (1) JPS62283936A (en)
KR (1) KR870010872A (en)
AT (1) ATE59782T1 (en)
AU (1) AU7338587A (en)
CA (1) CA1306677C (en)
DE (2) DE3617824A1 (en)
DK (1) DK268287A (en)
ES (1) ES2033258T3 (en)
GR (1) GR3001558T3 (en)
IL (1) IL82639A0 (en)
PT (1) PT84946B (en)
ZA (1) ZA873771B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3806852A1 (en) * 1988-03-03 1989-09-14 Knoll Ag NEW (ALPHA) AMINODICARBONIC ACID DERIVATIVES, THEIR PRODUCTION AND USE
US5686100A (en) * 1994-11-22 1997-11-11 E.R. Squibb & Sons, Inc. Prophylactic and therapeutic treatment of skin sensitization and irritation
DE10223932A1 (en) * 2002-05-29 2003-12-18 Rudolf Wank Use of diuretics to treat swelling
GB0517838D0 (en) * 2005-09-02 2005-10-12 Henderson Morley Plc Transdermal active principle delivery means

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3238102A (en) * 1961-07-14 1966-03-01 Taisho Pharmaceutical Co Ltd Solubilization of hydrocortisone acetate
US3175949A (en) * 1962-01-08 1965-03-30 Bristol Myers Co Emulsion of mineral oil, lauric diethanolamide, and water
CA1154024A (en) * 1980-04-17 1983-09-20 Werner Schafer Transdermal carrier materials
DE3025367A1 (en) * 1980-07-04 1982-01-28 Hoechst Ag, 6000 Frankfurt SALT FROM FUROSEMIDE OR PIRETANIDE AS ACIDIC COMPONENT AND PENBUTOLOL OR (-) - 3- (4- (3- (3,4-DIMETHOXYPHENYLAETHYLAMINO) -2-HYDROXY-PROPOXY) -PHENYL) -CROTONSAEURENESINESESSENESE DIESELESSENESE ALSINE DIESE ALSINE DIESE ALSINE DIESE ALENESE, DIONESE, DIONESE, DIESE, INC CONTAINING AGENT AND ITS USE
EP0139127A1 (en) * 1983-08-22 1985-05-02 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Transdermal drug delivery device and its preparation
JPS61103840A (en) * 1984-10-26 1986-05-22 Nitto Electric Ind Co Ltd Dermatologic administration composition

Also Published As

Publication number Publication date
IL82639A0 (en) 1987-11-30
KR870010872A (en) 1987-12-18
EP0247507B1 (en) 1991-01-09
ES2033258T3 (en) 1993-03-16
AU7338587A (en) 1987-12-03
EP0247507A2 (en) 1987-12-02
DE3767212D1 (en) 1991-02-14
ATE59782T1 (en) 1991-01-15
JPS62283936A (en) 1987-12-09
DK268287D0 (en) 1987-05-26
DE3617824A1 (en) 1987-12-03
DK268287A (en) 1987-11-28
CA1306677C (en) 1992-08-25
PT84946A (en) 1987-06-01
GR3001558T3 (en) 1992-11-23
PT84946B (en) 1989-07-21
EP0247507A3 (en) 1988-02-10

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