ZA873007B - Novel benzo(de)isoquinoline-1,3-diones,their preparation and their use - Google Patents

Novel benzo(de)isoquinoline-1,3-diones,their preparation and their use

Info

Publication number
ZA873007B
ZA873007B ZA873007A ZA873007A ZA873007B ZA 873007 B ZA873007 B ZA 873007B ZA 873007 A ZA873007 A ZA 873007A ZA 873007 A ZA873007 A ZA 873007A ZA 873007 B ZA873007 B ZA 873007B
Authority
ZA
South Africa
Prior art keywords
diones
isoquinoline
preparation
novel benzo
benzo
Prior art date
Application number
ZA873007A
Other languages
English (en)
Inventor
Miguel Fernandez Brana
Fernandez Brana Miguel
Jose Maria Castellano Berlanga
Maria Castellano Berlanga Jose
Erich Schlick
Schlick Erich
Gerhard Keilhauer
Keilhauer Gerhard
Original Assignee
Knoll Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Knoll Ag filed Critical Knoll Ag
Publication of ZA873007B publication Critical patent/ZA873007B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D221/00Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04Ortho- or peri-condensed ring systems
    • C07D221/06Ring systems of three rings
    • C07D221/14Aza-phenalenes, e.g. 1,8-naphthalimide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
ZA873007A 1986-04-29 1987-04-28 Novel benzo(de)isoquinoline-1,3-diones,their preparation and their use ZA873007B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19863614414 DE3614414A1 (de) 1986-04-29 1986-04-29 Neue benzo(de)isochinolin-1,3-dione, ihre herstellung und verwendung

Publications (1)

Publication Number Publication Date
ZA873007B true ZA873007B (en) 1989-01-25

Family

ID=6299742

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA873007A ZA873007B (en) 1986-04-29 1987-04-28 Novel benzo(de)isoquinoline-1,3-diones,their preparation and their use

Country Status (9)

Country Link
EP (1) EP0243841A1 (xx)
JP (1) JPS6322078A (xx)
AU (1) AU7212587A (xx)
DE (1) DE3614414A1 (xx)
DK (1) DK215187A (xx)
FI (1) FI871850A (xx)
HU (1) HUT44517A (xx)
NO (1) NO871766L (xx)
ZA (1) ZA873007B (xx)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3635711A1 (de) * 1986-10-21 1988-04-28 Knoll Ag 5-nitrobenzo(de)isochinolin-1,3-dione, ihre herstellung und verwendung
US5202318A (en) * 1990-05-14 1993-04-13 Syntex (U.S.A.) Inc. Tricyclic compounds acting at serotonin receptor subtypes
CA2351348A1 (en) * 1998-11-25 2000-06-02 Merck Patent Gesellschaft Mit Beschraenkter Haftung Substituted benzo[de]isoquinoline-1,3-diones
US6693198B2 (en) * 2002-04-22 2004-02-17 Xanthus Life Sciences, Inc. Amonafide salts
JP2007536283A (ja) * 2004-05-05 2007-12-13 ユニバイオスクリーン エス.アー. ナフタルイミド誘導体、それらの製造方法、およびそれらの医薬組成物
CN104994853B (zh) 2012-09-28 2018-11-30 协同医药发展有限公司 用于治疗cns、肿瘤学疾病和相关病症的二氢-6-氮杂非那烯衍生物
CN110194741B (zh) * 2019-07-08 2022-09-09 桂林医学院 4-苯甲酰哌嗪-3-硝基-1,8-萘酰亚胺衍生物及其制备方法和应用
CN115385890B (zh) * 2022-07-19 2023-08-08 杭州庆正鸿科技有限公司 一种1,8萘酰亚胺衍生物及其制备方法与应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2423548C2 (de) * 1974-05-15 1984-08-23 Hoechst Ag, 6230 Frankfurt Verfahren zur Herstellung von 4-Amino1,8-naphthalimid-Verbindungen
EP0125439B1 (en) * 1983-04-01 1990-01-24 Warner-Lambert Company 3,6-disubstituted-1,8-naphthalimides and methods for their production and use

Also Published As

Publication number Publication date
FI871850A0 (fi) 1987-04-28
NO871766D0 (no) 1987-04-28
DK215187D0 (da) 1987-04-28
FI871850A (fi) 1987-10-30
EP0243841A1 (de) 1987-11-04
DE3614414A1 (de) 1987-11-05
JPS6322078A (ja) 1988-01-29
HUT44517A (en) 1988-03-28
AU7212587A (en) 1987-11-05
DK215187A (da) 1987-10-30
NO871766L (no) 1987-10-30

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