ZA872690B - Synergistic combination of amantadine and selegiline - Google Patents

Synergistic combination of amantadine and selegiline

Info

Publication number
ZA872690B
ZA872690B ZA872690A ZA872690A ZA872690B ZA 872690 B ZA872690 B ZA 872690B ZA 872690 A ZA872690 A ZA 872690A ZA 872690 A ZA872690 A ZA 872690A ZA 872690 B ZA872690 B ZA 872690B
Authority
ZA
South Africa
Prior art keywords
selegiline
amantadine
synergistic combination
combination
synergistic
Prior art date
Application number
ZA872690A
Other languages
English (en)
Inventor
Dirk Reischig
Reischig Dirk
Helmut Hettche
Hettche Helmut
Wolfgang Brade
Brade Wolfgang
Original Assignee
Degussa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Degussa filed Critical Degussa
Publication of ZA872690B publication Critical patent/ZA872690B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A61K31/315—Zinc compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Luminescent Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
ZA872690A 1986-04-16 1987-04-14 Synergistic combination of amantadine and selegiline ZA872690B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3612702 1986-04-16

Publications (1)

Publication Number Publication Date
ZA872690B true ZA872690B (en) 1988-03-30

Family

ID=6298731

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA872690A ZA872690B (en) 1986-04-16 1987-04-14 Synergistic combination of amantadine and selegiline

Country Status (19)

Country Link
US (1) US4812481A (xx)
EP (1) EP0241809B1 (xx)
JP (1) JPS62249923A (xx)
AT (1) ATE55245T1 (xx)
AU (1) AU598533B2 (xx)
CA (1) CA1298200C (xx)
DD (1) DD259352A5 (xx)
DE (1) DE3764144D1 (xx)
DK (1) DK168514B1 (xx)
ES (1) ES2029805T3 (xx)
FI (1) FI871668A (xx)
GR (1) GR3000707T3 (xx)
HU (1) HU197840B (xx)
IE (1) IE60245B1 (xx)
IL (1) IL82216A0 (xx)
NO (1) NO871581L (xx)
PL (1) PL265152A1 (xx)
PT (1) PT84684B (xx)
ZA (1) ZA872690B (xx)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4861800A (en) * 1987-08-18 1989-08-29 Buyske Donald A Method for administering the drug deprenyl so as to minimize the danger of side effects
GB8807504D0 (en) * 1988-03-29 1988-05-05 Sandoz Ltd Improvements in/relating to organic compounds
HU208484B (en) * 1988-08-17 1993-11-29 Chinoin Gyogyszer Es Vegyeszet Process for producing pharmaceutical composition containing acid additional salt of selegilin as active component for treating schisofrenia
AU654143B2 (en) * 1990-06-25 1994-10-27 Du Pont Merck Pharmaceutical Company, The Amantadine hydrochloride suspension with enhanced dissolution characteristics for use in soft gelatin capsules
US5175002A (en) * 1991-10-02 1992-12-29 Du Pont Merck Pharmaceutical Company Amantadine hydrochloride syspension with enhanced dissolution characteristics for use in soft gelatin capsules
WO1993009229A1 (en) 1991-11-04 1993-05-13 Genetics Institute, Inc. Recombinant bone morphogenetic protein heterodimers, compositions and methods of use
HUT63579A (en) * 1991-12-20 1993-09-28 Chinoin Gyogyszer Es Vegyeszet Process for producing double-phase pharmaceutical compositions suitable for treating diseases occurring during neurodegenerative processes
US5817336A (en) * 1993-04-02 1998-10-06 Orion-Yhtyma Oy Composition containing selegiline
US5484608A (en) * 1994-03-28 1996-01-16 Pharmavene, Inc. Sustained-release drug delivery system
GB9426079D0 (en) * 1994-12-23 1995-02-22 Orion Yhtymae Oy A gelatine capsule
US6319954B1 (en) 1995-01-13 2001-11-20 Somerset Pharmaceuticals, Inc. S-(+)-desmethylselegiline and its use in the therapeutic methods and pharmaceutical compositions
US6348208B1 (en) * 1995-01-13 2002-02-19 Somerset Pharmaceuticals, Inc. Methods and pharmaceutical compositions employing desmethylselegiline
US6033682A (en) 1995-01-13 2000-03-07 Somerset Pharmaceuticals, Inc. S(+) desmethylselegiline and its use in therapeutic methods and pharmaceutical compositions
US6299901B1 (en) 1995-01-13 2001-10-09 Somerset Pharmaceuticals, Inc. Methods and pharmaceutical compositions employing desmethylselegiline
DE19533772C1 (de) * 1995-09-12 1998-01-02 Hexal Ag Tacrin/Selegilin-Pflaster
DK0866691T4 (da) * 1995-11-06 2005-06-06 Somerset Pharmaceuticals Inc Medikamenter til sublingual og bukkal administration af selegilin
DE19716905C1 (de) * 1997-04-22 1998-08-27 Iip Inst Fuer Ind Pharmazie Fo Stabile, wäßrige Lösung auf der Grundlage von Selegilin und Vorrichtung zu ihrer Verabreichung
GB9715082D0 (en) * 1997-07-17 1997-09-24 Scherer Ltd R P Treatment of attention deficit hyperactivity disorder and narcolepsy
BR9908713A (pt) 1998-03-16 2000-11-21 Somerset Pharmaceuticals Inc Uso de selegilina ou desmetil-selegilina para tratamento de feridas, queimaduras e danos dermatológicos
WO2001034172A2 (en) * 1999-11-05 2001-05-17 Vela Pharmaceuticals Inc. Methods and compositions for treating reward deficiency syndrome
US20040122090A1 (en) * 2001-12-07 2004-06-24 Lipton Stuart A. Methods for treating neuropsychiatric disorders with nmda receptor antagonists
JP2005525377A (ja) * 2002-03-04 2005-08-25 サマセット ファーマシューティカルズ， インコーポレイテッド デスメチルセレジリンの投与による末梢神経障害の予防および処置のための方法
WO2004096141A2 (en) * 2003-04-25 2004-11-11 Indevus Pharmaceuticals, Inc. Method for promoting uninterrupted sleep by administration of trospium chloride
DE10338174A1 (de) * 2003-08-20 2005-03-24 Lts Lohmann Therapie-Systeme Ag Transdermale Arzneimittelzubereitungen mit Wirkstoffkombinationen zur Behandlung der Parkinson-Krankheit
ES2282904T3 (es) 2003-09-12 2007-10-16 Wyeth Barras solidas de fosfato calcico inyectables para el suministro de proteinas osteogenicas.
CA2554959A1 (en) * 2004-01-29 2005-08-11 Neuromolecular, Inc. Combination of a nmda receptor antagonist and a mao-inhibitor or a gadpf-inhibitor for the treatment of central nervous system-related conditions
AU2005215775B2 (en) * 2004-02-13 2011-02-03 Neuromolecular, Inc. Combination of a NMDA receptor antagonist and an anti-depressive drug MAO-inhibitor or a GADPH-inhibitor for the treatment of psychiatric conditions
US7619007B2 (en) 2004-11-23 2009-11-17 Adamas Pharmaceuticals, Inc. Method and composition for administering an NMDA receptor antagonist to a subject
CA2588296A1 (en) 2004-11-24 2006-06-01 Neuromolecular Pharmaceuticals, Inc. Composition comprising an nmda receptor antagonist and levodopa and use thereof for treating neurological disease
US20060264478A1 (en) * 2005-02-22 2006-11-23 Northwestern University Methods and compositions for modulating calcium channels
EP2982372B1 (en) 2005-04-05 2020-08-05 Yale University Glutamate modulating agents in the treatment of mental disorders
WO2006121560A2 (en) 2005-04-06 2006-11-16 Adamas Pharmaceuticals, Inc. Methods and compositions for treatment of cns disorders
US8969417B2 (en) † 2008-06-06 2015-03-03 Pharmatwob Ltd. Pharmaceutical compositions for treatment of Parkinsons disease
BR112012013487A2 (pt) 2009-12-02 2017-10-03 Adamas Pharmaceuticals Inc Composições de amantadina e métodos de uso
US10154971B2 (en) 2013-06-17 2018-12-18 Adamas Pharma, Llc Methods of administering amantadine

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE314077C (xx) *
AT314077B (de) * 1972-01-07 1974-03-25 Hurka Wilhelm Verfahren zur Herstellung eines neuen, gegen den Parkinsonismus wirksamen Kombinationspräparates
HU193662B (en) * 1983-12-20 1987-11-30 Chinoin Gyogyszer Es Vegyeszet Process for producing synergetic pharmaceutical composition of antidepressive aktivity

Also Published As

Publication number Publication date
DK197787A (da) 1987-10-17
DK197787D0 (da) 1987-04-15
JPS62249923A (ja) 1987-10-30
NO871581L (no) 1987-10-19
EP0241809B1 (de) 1990-08-08
AU7154187A (en) 1987-10-29
PL265152A1 (en) 1988-07-07
HUT43789A (en) 1987-12-28
ATE55245T1 (de) 1990-08-15
CA1298200C (en) 1992-03-31
FI871668A (fi) 1987-10-17
EP0241809A1 (de) 1987-10-21
IE60245B1 (en) 1994-06-15
GR3000707T3 (en) 1991-10-10
IL82216A0 (en) 1987-10-30
ES2029805T3 (es) 1992-10-01
HU197840B (en) 1989-06-28
AU598533B2 (en) 1990-06-28
PT84684A (de) 1987-05-01
DK168514B1 (da) 1994-04-11
NO871581D0 (no) 1987-04-14
US4812481A (en) 1989-03-14
FI871668A0 (fi) 1987-04-15
IE870973L (en) 1987-10-16
DE3764144D1 (de) 1990-09-13
DD259352A5 (de) 1988-08-24
PT84684B (pt) 1989-12-29

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