ZA872263B - Indole derivatives,processes for their preparation and pharmaceutical composition for the treatment for migraine - Google Patents

Indole derivatives,processes for their preparation and pharmaceutical composition for the treatment for migraine

Info

Publication number
ZA872263B
ZA872263B ZA872263A ZA872263A ZA872263B ZA 872263 B ZA872263 B ZA 872263B ZA 872263 A ZA872263 A ZA 872263A ZA 872263 A ZA872263 A ZA 872263A ZA 872263 B ZA872263 B ZA 872263B
Authority
ZA
South Africa
Prior art keywords
migraine
processes
preparation
treatment
pharmaceutical composition
Prior art date
Application number
ZA872263A
Other languages
English (en)
Inventor
William Oxford Alexander
Dennis Dowle Michael
Original Assignee
Glaxo Group Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Limited filed Critical Glaxo Group Limited
Publication of ZA872263B publication Critical patent/ZA872263B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16—Tryptamines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
ZA872263A 1986-03-27 1987-03-27 Indole derivatives,processes for their preparation and pharmaceutical composition for the treatment for migraine ZA872263B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB868607824A GB8607824D0 (en) 1986-03-27 1986-03-27 Chemical compounds

Publications (1)

Publication Number Publication Date
ZA872263B true ZA872263B (en) 1988-01-13

Family

ID=10595430

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA872263A ZA872263B (en) 1986-03-27 1987-03-27 Indole derivatives,processes for their preparation and pharmaceutical composition for the treatment for migraine

Country Status (6)

Country Link
US (1) US4795756A (fr)
EP (1) EP0244085A3 (fr)
JP (1) JPS6317860A (fr)
AU (1) AU602888B2 (fr)
GB (1) GB8607824D0 (fr)
ZA (1) ZA872263B (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5225431A (en) * 1987-10-23 1993-07-06 Burroughs Wellcome Co. Therapeutic substituted indole compounds and compositions thereof
US5059603A (en) * 1989-06-12 1991-10-22 Centuries Laboratories, Inc. Method and composition for treating impotence
PT97888B (pt) * 1990-06-07 1998-12-31 Zeneca Ltd Processo para a preparacao de compostos heterociclicos derivados de indol e de composicoes farmaceuticas que os contem
GB9211277D0 (en) 1992-05-28 1992-07-15 Glaxo Group Inc Pharmaceutical compositions
US7189753B1 (en) 1997-11-06 2007-03-13 Cady Roger K Preemptive prophylaxis of migraine

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA795239B (en) * 1978-10-12 1980-11-26 Glaxo Group Ltd Heterocyclic compounds
GB2082175B (en) * 1980-08-12 1984-05-02 Glaxo Group Ltd Heterocyclic compounds
NZ197998A (en) * 1980-08-12 1985-08-16 Glaxo Group Ltd 5-amino(methyl)-1h-indol-3-ylalkaneamines
ZW19381A1 (en) * 1980-08-12 1983-03-09 Glaxo Group Ltd Heterocyclic compounds
NZ197996A (en) * 1980-08-12 1985-08-16 Glaxo Group Ltd 1-(3-(omega-aminoalkyl)-1h-indol-5-yl)alkanamides
GB8431426D0 (en) * 1984-12-13 1985-01-23 Glaxo Group Ltd Chemical compounds

Also Published As

Publication number Publication date
US4795756A (en) 1989-01-03
AU602888B2 (en) 1990-11-01
AU7072087A (en) 1987-10-01
EP0244085A2 (fr) 1987-11-04
GB8607824D0 (en) 1986-04-30
JPS6317860A (ja) 1988-01-25
EP0244085A3 (fr) 1988-04-20

Similar Documents

Publication Publication Date Title
IL83467A0 (en) Imidazole derivatives,processes for their preparation and pharmaceutical compositions containing the same
IL84522A0 (en) Imidazopyridine derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
IL81201A (en) Indole derivatives,their preparation and pharmaceutical compositions containing them
IL92798A0 (en) Benzimidazole derivatives,process for their preparation and pharmaceutical compositions containing them
IL71310A0 (en) Benzimidazole derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
EP0240015A3 (en) Carbostyril derivatives, process for preparing them, pharmaceutical composition, and use
ZA849499B (en) Indole derivatives,processes for their preparation and pharmaceutical compositions containing them
IL83760A (en) 3-pyrazoliomethyl-3- cephem-4-carboxylate derivatives, process for the preparation thereof, and pharmacetuical compositions containing the same
IL106737A0 (en) Indole and indoline derivatives, process for their preparation and use as medicament
IL84913A0 (en) Alkanesulfonanilide derivatives,processes for preparation thereof and pharmaceutical composition comprising the same
IL88903A (en) Indolylpiperidine derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same
GB8917687D0 (en) Aminopiperazine derivatives,processes for preparation thereof and pharmaceutical composition comprising the same
AU6741887A (en) Indole derivatives, processes for their preparation and pharmaceutical compositions containing them
IL87563A (en) Isoxazole-b-carboline derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same
IL73888A (en) Ortho-condensed pyrrole derivatives,process for the preparation thereof and pharmaceutical compositions comprising the same
EP0285089A3 (en) 4-thioquinazoline derivatives, processes for their preparation and pharmaceutical compositions
EP0264744A3 (en) Process for the preparation of 4,4'-diaminodiphenylmethane and its derivatives.
ZA872263B (en) Indole derivatives,processes for their preparation and pharmaceutical composition for the treatment for migraine
IL86269A0 (en) Imidazole derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
IL86173A0 (en) Pyrrolidine derivatives,processes for the preparation thereof and pharmaceutical compositions containing them
ZA871756B (en) Arylazolylmethylbenzocycloalkene derivatives,processes for the preparation thereof,and the use thereof
EP0246861A3 (en) Pharmaceutical composition based on crotoxine, process for preparing the active component and the pharmaceutical composition
IL82294A0 (en) 1,3-dihydropyridine derivatives,process for the preparation thereof and pharmaceutical compositions containing the same
IL91332A0 (en) Mitomycin derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
IL81978A (en) Indenopyrimidine derivatives,process for their preparation and pharmaceutical compositions containing them