ZA863789B - Process for the in vitro immunization of human splenocytes against tumor associated antigens - Google Patents

Process for the in vitro immunization of human splenocytes against tumor associated antigens

Info

Publication number
ZA863789B
ZA863789B ZA863789A ZA863789A ZA863789B ZA 863789 B ZA863789 B ZA 863789B ZA 863789 A ZA863789 A ZA 863789A ZA 863789 A ZA863789 A ZA 863789A ZA 863789 B ZA863789 B ZA 863789B
Authority
ZA
South Africa
Prior art keywords
associated antigens
tumor associated
against tumor
vitro immunization
human splenocytes
Prior art date
Application number
ZA863789A
Other languages
English (en)
Inventor
May-Kin Ho
Original Assignee
Du Pont
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont filed Critical Du Pont
Publication of ZA863789B publication Critical patent/ZA863789B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10Cells modified by introduction of foreign genetic material
    • C12N5/12Fused cells, e.g. hybridomas
    • C12N5/16Animal cells
    • C12N5/163Animal cells one of the fusion partners being a B or a T lymphocyte
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
ZA863789A 1985-05-22 1986-05-21 Process for the in vitro immunization of human splenocytes against tumor associated antigens ZA863789B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/736,660 US5106746A (en) 1985-05-22 1985-05-22 Process for the in vitro immunization of human splenocytes against tumor associated antigens

Publications (1)

Publication Number Publication Date
ZA863789B true ZA863789B (en) 1988-01-27

Family

ID=24960774

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA863789A ZA863789B (en) 1985-05-22 1986-05-21 Process for the in vitro immunization of human splenocytes against tumor associated antigens

Country Status (9)

Country Link
US (1) US5106746A (el)
EP (1) EP0202642A3 (el)
JP (1) JPS61271983A (el)
AU (1) AU591901B2 (el)
DK (1) DK237186A (el)
GR (1) GR861342B (el)
IL (1) IL78869A (el)
NZ (1) NZ216249A (el)
ZA (1) ZA863789B (el)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1341552C (en) * 1988-09-23 2007-10-02 Kenneth Alonso Method of producing human-human hybridomas, the production of monoclonal and polyclonal antibodies therefrom, and therapeutic use thereof
DE4422020A1 (de) * 1993-07-29 1995-02-02 Bernhard Heising Pharmazeutische Zusammensetzung
JPH08510470A (ja) * 1993-07-29 1996-11-05 ハイジン,バーンハルト Tリンパ球を含有する感染症治療用医薬組成物
US6713250B1 (en) 1997-08-08 2004-03-30 The Research Foundation Of State University Of New York Identification of human allergens and T-lymphocyte antigens in vitro
US7572631B2 (en) * 2000-02-24 2009-08-11 Invitrogen Corporation Activation and expansion of T cells
US7541184B2 (en) * 2000-02-24 2009-06-02 Invitrogen Corporation Activation and expansion of cells
US20050084967A1 (en) * 2002-06-28 2005-04-21 Xcyte Therapies, Inc. Compositions and methods for eliminating undesired subpopulations of T cells in patients with immunological defects related to autoimmunity and organ or hematopoietic stem cell transplantation
US20040175373A1 (en) * 2002-06-28 2004-09-09 Xcyte Therapies, Inc. Compositions and methods for eliminating undesired subpopulations of T cells in patients with immunological defects related to autoimmunity and organ or hematopoietic stem cell transplantation
JP2006506987A (ja) * 2002-06-28 2006-03-02 エクサイト セラピーズ インコーポレーティッド 自己免疫および臓器または造血幹細胞移植に関連する免疫学的欠損を有する患者における免疫レパートリー回復のための組成物および方法
JP5414535B2 (ja) * 2007-12-03 2014-02-12 株式会社アドバンス 1本鎖抗体scFvの製造方法
US11911451B2 (en) 2017-08-22 2024-02-27 ImmuLogix Ltd Composition of tumor-associated proliferative peptides and related anti-cancer immunogen for the treatment of lung cancers and other cancers

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4322879A (en) * 1978-01-11 1979-07-19 Massachusetts General Hospital, The Producing antibodies
US4444887A (en) * 1979-12-10 1984-04-24 Sloan-Kettering Institute Process for making human antibody producing B-lymphocytes
US4668629A (en) * 1980-07-18 1987-05-26 The Board Of Trustees Of Leland Stanford Jr. University Human hybridomas, precursors and products
JPS58201994A (ja) * 1982-05-21 1983-11-25 Hideaki Hagiwara 抗原特異的ヒト免疫グロブリンの生産方法
CA1214123A (en) * 1983-01-20 1986-11-18 Masashi Matsui Cell lines for use in the preparation of hybridoma cells

Also Published As

Publication number Publication date
DK237186A (da) 1986-11-23
AU591901B2 (en) 1989-12-21
US5106746A (en) 1992-04-21
AU5781886A (en) 1986-11-27
GR861342B (en) 1986-09-23
IL78869A0 (en) 1986-09-30
JPS61271983A (ja) 1986-12-02
EP0202642A2 (en) 1986-11-26
IL78869A (en) 1990-07-26
NZ216249A (en) 1988-04-29
DK237186D0 (da) 1986-05-21
EP0202642A3 (en) 1989-03-15

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