ZA858001B - 1,3-bis(1h-1,2,4-triazol-1-yl)-2-fluoro-2(2,4-difluorophenyl)propane,antifungal composition containing it,and process for preparation of the compound and the composition - Google Patents

1,3-bis(1h-1,2,4-triazol-1-yl)-2-fluoro-2(2,4-difluorophenyl)propane,antifungal composition containing it,and process for preparation of the compound and the composition

Info

Publication number
ZA858001B
ZA858001B ZA858001A ZA858001A ZA858001B ZA 858001 B ZA858001 B ZA 858001B ZA 858001 A ZA858001 A ZA 858001A ZA 858001 A ZA858001 A ZA 858001A ZA 858001 B ZA858001 B ZA 858001B
Authority
ZA
South Africa
Prior art keywords
difluorophenyl
triazol
fluoro
propane
bis
Prior art date
Application number
ZA858001A
Other languages
English (en)
Inventor
Jagdish Armitlal Desai
Alan Bruce Cooper
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of ZA858001B publication Critical patent/ZA858001B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
ZA858001A 1984-10-19 1985-10-17 1,3-bis(1h-1,2,4-triazol-1-yl)-2-fluoro-2(2,4-difluorophenyl)propane,antifungal composition containing it,and process for preparation of the compound and the composition ZA858001B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US66285684A 1984-10-19 1984-10-19

Publications (1)

Publication Number Publication Date
ZA858001B true ZA858001B (en) 1986-05-28

Family

ID=24659517

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA858001A ZA858001B (en) 1984-10-19 1985-10-17 1,3-bis(1h-1,2,4-triazol-1-yl)-2-fluoro-2(2,4-difluorophenyl)propane,antifungal composition containing it,and process for preparation of the compound and the composition

Country Status (6)

Country Link
EP (1) EP0178682A3 (xx)
JP (1) JPS61100572A (xx)
AU (1) AU4882685A (xx)
DK (1) DK476385A (xx)
IL (1) IL76750A0 (xx)
ZA (1) ZA858001B (xx)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8716651D0 (en) * 1987-07-15 1987-08-19 Ici Plc 2-propanol derivatives
DE3939492A1 (de) * 1989-11-29 1991-06-06 Mack Chem Pharm Pharmazeutische zubereitungen
WO2005006860A2 (en) * 2003-07-18 2005-01-27 The Board Of Governors For Higher Education State Of Rhode Island And Providence Plantations Azole derivatives and methods for making the same
CN102002054B (zh) * 2010-10-25 2013-05-15 天津药物研究院 一种吡唑类化合物及其制备方法和用途

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2078719B (en) * 1980-06-02 1984-04-26 Ici Ltd Heterocyclic compounds
GR79307B (xx) * 1982-06-09 1984-10-22 Pfizer

Also Published As

Publication number Publication date
AU4882685A (en) 1986-04-24
DK476385D0 (da) 1985-10-17
DK476385A (da) 1986-04-20
EP0178682A2 (en) 1986-04-23
JPS61100572A (ja) 1986-05-19
IL76750A0 (en) 1986-02-28
EP0178682A3 (en) 1986-12-30

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